Abstract: Curcuma longa - haladi, a plant grown as a spice is an entity known to have significant antimicrobial potency. This study was carried out to analyze its bio-active components, with the help of High Performance Thin Layer Chromatography (HPTLC). Anti-microbial effects of C. longa were checked using aqueous and acetone extracts, against a few bacterial pathogens causing common infections. The aqueous extract was found effective in inhibiting the growth of eight pathogens (64% efficiency) while the acetone extract in inhibiting the growth of three pathogens (21% efficiency). Flavonoid analysis of aqueous extract by HPTLC showed peaks probably corresponding to Coumarins, Triterpenoids, Echinacosides, Eriodictyl, Cichoric acid and Caffeic acid derivatives, responsible for its anti-microbial activities. This natural bio resource may prove to be of significance in the armamentarium of antimicrobial agents.Abstract: Curcuma longa - haladi, a plant grown as a spice is an entity known to have significant antimicrobial potency. This study was carried out to analyze its bio-active components, with the help of High Performance Thin Layer Chromatography (HPTLC). Anti-microbial effects of C. longa were checked using aqueous and acetone extracts, against a few bacteri...Show More