Archive:: American Journal of Internal Medicine:: Science Publishing Group

Volume 12, Issue 6, December 2024

Research Article
Adult-onset Still's Disease in a Health Center: A Report of 10 Cases

Jean Noel Diokel Ndour^*, Bachir Mansour Diallo, Fulgence Faye, Aicha Kaneye, Melissa Derneville, Eunice Thiendrbéogo, Amy Dioum, Atoumane Faye, Adama Berthé, Papa Souleymane Touré, Madoky Magatte Diop, Mamadou Mourtalla Ka

Issue: Volume 12, Issue 6, December 2024

Pages: 104-109

Received: 20 September 2024

Accepted: 11 October 2024

Published: 13 November 2024

DOI: 10.11648/j.ajim.20241206.11

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Abstract: Introduction: Adult-onset Still's disease is a rare systemic inflammatory disease in Africa. Observations have been published in Senegal. Materials and Methods: We conducted a retrospective descriptive study to establish the epidemiological profile of patients presenting with adult-onset Still's disease (AOSD) in a health center. The patients inclu... Show More

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Research Article
Therapeutic Benefit of Ursodeoxycholic Acid in Tamoxifen-Induced Hepatotoxicity in Rats

Elias Adikwu^*, Tobechi Brendan Nnanna, Bonsome Bokolo

Issue: Volume 12, Issue 6, December 2024

Pages: 110-119

Received: 27 September 2024

Accepted: 25 October 2024

Published: 18 November 2024

DOI: 10.11648/j.ajim.20241206.12

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Abstract: The use of tamoxifen (TAM) for breast cancer treatment may cause hepatotoxicity. Ursodeoxycholic acid (UDCA) is a potential liver protective chemical compound. The protective effect of UDCA on TAM-induced hepatotoxicity in rats was analyzed in this study. Thirty five adult female Wistar rats grouped into 7 of n=5/group were used. The rats were trea... Show More

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