Myofascial Techniques as a Part of the Treatment of Nonspecific Low Back Pain
Dimitorva Vesela,
Sazdova Lyubomira
Issue:
Volume 7, Issue 2, June 2022
Pages:
16-19
Received:
24 October 2021
Accepted:
15 March 2022
Published:
7 May 2022
DOI:
10.11648/j.rs.20220702.11
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Abstract: Preliminary clinical study for patients with Nonspecific low back pain. The aim of the study is to present techniques for myofascial treatment and to determine their effectiveness in patients with nonspecific low back pain (NSLBP). Methodology: Myofascial treatment techniques are presented combined with specific fascial exercises and their effectiveness is estimated in 25 patients with nonspecific low back pain. Outcome measures include assessment of pain intensity by Visual Analogue Scale (VAS), Slump test, discriminatory sensibility and mobility test. All patients were assessed prior to the start of the therapy and at the follow-up at the 1st month. Results: Myofascial therapy combined with specific exercises produced statistically significant improvement in both pain and function in our patients suffering from nonspecific low back pain. Conclusions: The outcomes confirm the effectiveness of the techniques and they could be successfully implemented as a part of existing physiotherapeutic programs for patients with nonspecific low back pain. Due to the short follow up, we suggest considering the data as preliminary findings and further research is needed.
Abstract: Preliminary clinical study for patients with Nonspecific low back pain. The aim of the study is to present techniques for myofascial treatment and to determine their effectiveness in patients with nonspecific low back pain (NSLBP). Methodology: Myofascial treatment techniques are presented combined with specific fascial exercises and their effectiv...
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Acute Toxicity Evaluation and Safety Study of Allogeneic Wharton’s Jelly-Derived Mesenchymal Stromal Cells Therapy in the Animal Model
Jaianand Kannaiyan,
Pavankumar Shukla,
Firdosh Mahuvawalla
Issue:
Volume 7, Issue 2, June 2022
Pages:
20-28
Received:
16 March 2022
Accepted:
11 April 2022
Published:
12 May 2022
DOI:
10.11648/j.rs.20220702.12
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Abstract: In-vitro and in-vivo investigations using ex vivo-expanded human Wharton’s jelly-derived mesenchymal stromal cells (WJMSCs) isolated from single donors has shown therapeutic advantages. Clinical grade expansion, safety, and acute toxicity of Wharton’s jelly-derived mesenchymal stromal cells isolated from five healthy donors were evaluated in Wistar Albino Rats via intravenous and subcutaneous routes in this study. The expression of several cell surface markers, differentiation capacity, and immunomodulatory activities of the isolated WJMSCs were all evaluated. In a series of preclinical investigations, the clinical grade expanded cells were given to rodents by intravenous and subcutaneous methods to examine their in-vivo safety, overall toxicity, and tumorigenic potential. We confirmed that WJ cells exhibit morphological and phenotypic features that are comparable to MSCs. In rats, the study found no mortality, aberrant clinical symptoms, or significant pathological alterations at varied dosages administered intravenously or subcutaneously. Furthermore, rats tolerated repeated treatment of WJMSCs well, with no evidence of prenatal harm in the same animal species. The WJMSCs were shown to be non-toxic, non-teratogenic, and non-tumorigenic in Wistar Albino Rats. More research is needed to see if it can be safely supplied to human patients.
Abstract: In-vitro and in-vivo investigations using ex vivo-expanded human Wharton’s jelly-derived mesenchymal stromal cells (WJMSCs) isolated from single donors has shown therapeutic advantages. Clinical grade expansion, safety, and acute toxicity of Wharton’s jelly-derived mesenchymal stromal cells isolated from five healthy donors were evaluated in Wistar...
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Meta-Analysis of Acupoint Massage in the Treatment of Dysphagia After Stroke
Xueting Jing,
Shiying Tang
Issue:
Volume 7, Issue 2, June 2022
Pages:
29-36
Received:
12 June 2022
Accepted:
21 June 2022
Published:
30 June 2022
DOI:
10.11648/j.rs.20220702.13
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Abstract: Background: At present, the burden of stroke is very heavy. Dysphagia is one of the complications of stroke, and its incidence is very high. Dysphagia can lead to malnutrition, aspiration pneumonia, and other conditions, which seriously affect the prognosis and quality of life of patients. Promoting the functional recovery of patients with dysphagia after stroke is one of the urgent clinical problems to be solved. Objective: To evaluate the efficacy of acupoint massage in the treatment of dysphagia after stroke, and to provide evidence for the rehabilitation training program of dysphagia. Methods The clinical randomized controlled trials (RCTs) in PubMed, EMBASE, Cochrane Library, CNKI, Wanfang, China biomedical literature database (CBM) and, VIP database were searched by computer for the effect of acupoint massage as a rehabilitation intervention on dysphagia after stroke. The retrieval period is from January 2010 to November 26, 2021. Revman 5.3 software for meta-analysis. Results: A total of 13 RCTs were included in this study, with 1003 samples (500 in the intervention group and 503 in the control group). Meta-analysis showed that, compared with the control group, The improvement effective rate of water swallowing test in the head, face, and neck acupoint massage intervention group [OR = 3.71, 95%CI (2.54, 5.40), P < 0.001] was significantly increased, The standard swallowing assessment function scale score (SSA) [MD = -3.37, 95%CI (-5.20, -1.53), p = 0.0003] decreased significantly, and the difference was statistically significant. Conclusion: Current evidence shows that head, face, and neck acupoint massage can effectively promote the swallowing function rehabilitation of post-stroke patients with dysphagia, and has a synergistic effect with other rehabilitation training. It is an effective rehabilitation training method for dysphagia intervention.
Abstract: Background: At present, the burden of stroke is very heavy. Dysphagia is one of the complications of stroke, and its incidence is very high. Dysphagia can lead to malnutrition, aspiration pneumonia, and other conditions, which seriously affect the prognosis and quality of life of patients. Promoting the functional recovery of patients with dysphagi...
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