Synthesis, Characterization, Theoretical and Antimicrobial Evaluation of New Mn(II), Cu(II) and Zn(II) Complexes of Flavylium Salt

Omar H. Al-Obaidi

doi:doi:10.11648/j.ijbbmb.20160101.15

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Synthesis, Characterization, Theoretical and Antimicrobial Evaluation of New Mn(II), Cu(II) and Zn(II) Complexes of Flavylium Salt

Omar H. Al-Obaidi

Published in International Journal of Biochemistry, Biophysics & Molecular Biology (Volume 1, Issue 1)

Received: 17 September 2016 Accepted: 29 September 2016 Published: 26 October 2016

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Abstract

A new series of Mn(II), Cu(II) and Zn(II) complexes with the two ligands were prepared and spectroscopic method and elemental analysis verified their structures. The first ligand L1 is flavylium salt and the second L2 is a Flavon. Reaction between transition metal salts and the ligands have synthesized two groups of new metal complexes. These complexes have been identified by available spectroscopic tools (UV-visible and IR) the C.H.N results confirmed the proposed structures. The experimental data disclosed that the complexes were coordinated by 6-the coordinate with mono-and bidentate ligands forming octahedral structure, in which L2 acts as monodentate and L1, L2 as bidentate ligands. The metal linked with L1 through the oxygen in ortho position in ring B, were as the linkage of the metal with L3 takes place through the oxygen of the carbonyl group. A theoretical treatment of the formation of complexes in the gas phase was studied, this was done using the HYPERCHEM-6 program for the Molecular mechanics and Semi-empirical calculations. The antimicrobial activity of the ligand and its metal complexes were studied against the following strains of microorganism: Staphylococcus aureus and Escherichia coli by the well diffusion method. Metal complexes showed enhanced antimicrobial activity compared with that of the free ligand.

Published in	International Journal of Biochemistry, Biophysics & Molecular Biology (Volume 1, Issue 1)
DOI	10.11648/j.ijbbmb.20160101.15
Page(s)	31-35
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2016. Published by Science Publishing Group

Keywords

Flavylium Salt, Flavon, Metal Complexes, Antimicrobial Activity

References

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[4]	Teixeira S.; Siquet, C.; Aloes, C.; Boal, I.; Marques, M.P.; Borges, F.; Lima, J.L.F.C.; Reis, S. Structure-property studies on the antioxidant activity of flavonoids present in diet. Free Radic. Biol. Med. 2005, 39, 1099–1108.
[5]	Malesev, D.; Kuntic, V. Investigation of metal–flavonoid chelates and determination of flavonoids via metal– flavonoid complexing reactions. J. Serb. Chem. Soc. 2007, 72, 921–939.
[6]	Ferrer, E. G.; Salinas, M. V.; Correa, M. J.; Naso, L.; Barrio, D. A..; Etcheverry, S. B.; Lezama, L.; Rojo, T.; Williams, P. A. Synthesis, characterization, antitumoral and osteogenic activities of quercetin vanadyl (IV) complexes. J. Biol. Inorg. Chem. 2006, 11, 791–801.
[7]	Grazul, M.; Budzisz, E. Biological activity of metal ions complexes of chromones, coumarins and flavones. Coord. Chem. Rev. 2009, 253, 2588–2598.
[8]	E. Francesco, G. Salvatore, M. Luigi and C. Massimo, Phytochem., 68, 939 (2007).
[9]	Harborne J. B., et. al., “the Flavonoids”, Chapman and Hall, London (1975).
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[14]	H. X. Xu, M. Wan, H. Dong, P. But and L. Y. Foo, Biol. Pharm. Bull., 23, 1072 (2000).

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Omar H. Al-Obaidi. (2016). Synthesis, Characterization, Theoretical and Antimicrobial Evaluation of New Mn(II), Cu(II) and Zn(II) Complexes of Flavylium Salt. International Journal of Biochemistry, Biophysics & Molecular Biology, 1(1), 31-35. https://doi.org/10.11648/j.ijbbmb.20160101.15

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ACS Style

Omar H. Al-Obaidi. Synthesis, Characterization, Theoretical and Antimicrobial Evaluation of New Mn(II), Cu(II) and Zn(II) Complexes of Flavylium Salt. Int. J. Biochem. Biophys. Mol. Biol. 2016, 1(1), 31-35. doi: 10.11648/j.ijbbmb.20160101.15

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AMA Style

Omar H. Al-Obaidi. Synthesis, Characterization, Theoretical and Antimicrobial Evaluation of New Mn(II), Cu(II) and Zn(II) Complexes of Flavylium Salt. Int J Biochem Biophys Mol Biol. 2016;1(1):31-35. doi: 10.11648/j.ijbbmb.20160101.15

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@article{10.11648/j.ijbbmb.20160101.15,
  author = {Omar H. Al-Obaidi},
  title = {Synthesis, Characterization, Theoretical and Antimicrobial Evaluation of New Mn(II), Cu(II) and Zn(II) Complexes of Flavylium Salt},
  journal = {International Journal of Biochemistry, Biophysics & Molecular Biology},
  volume = {1},
  number = {1},
  pages = {31-35},
  doi = {10.11648/j.ijbbmb.20160101.15},
  url = {https://doi.org/10.11648/j.ijbbmb.20160101.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbbmb.20160101.15},
  abstract = {A new series of Mn(II), Cu(II) and Zn(II) complexes with the two ligands were prepared and spectroscopic method and elemental analysis verified their structures. The first ligand L1 is flavylium salt and the second L2 is a Flavon. Reaction between transition metal salts and the ligands have synthesized two groups of new metal complexes. These complexes have been identified by available spectroscopic tools (UV-visible and IR) the C.H.N results confirmed the proposed structures. The experimental data disclosed that the complexes were coordinated by 6-the coordinate with mono-and bidentate ligands forming octahedral structure, in which L2 acts as monodentate and L1, L2 as bidentate ligands. The metal linked with L1 through the oxygen in ortho position in ring B, were as the linkage of the metal with L3 takes place through the oxygen of the carbonyl group. A theoretical treatment of the formation of complexes in the gas phase was studied, this was done using the HYPERCHEM-6 program for the Molecular mechanics and Semi-empirical calculations. The antimicrobial activity of the ligand and its metal complexes were studied against the following strains of microorganism: Staphylococcus aureus and Escherichia coli by the well diffusion method. Metal complexes showed enhanced antimicrobial activity compared with that of the free ligand.},
 year = {2016}
}

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TY  - JOUR
T1  - Synthesis, Characterization, Theoretical and Antimicrobial Evaluation of New Mn(II), Cu(II) and Zn(II) Complexes of Flavylium Salt
AU  - Omar H. Al-Obaidi
Y1  - 2016/10/26
PY  - 2016
N1  - https://doi.org/10.11648/j.ijbbmb.20160101.15
DO  - 10.11648/j.ijbbmb.20160101.15
T2  - International Journal of Biochemistry, Biophysics & Molecular Biology
JF  - International Journal of Biochemistry, Biophysics & Molecular Biology
JO  - International Journal of Biochemistry, Biophysics & Molecular Biology
SP  - 31
EP  - 35
PB  - Science Publishing Group
SN  - 2575-5862
UR  - https://doi.org/10.11648/j.ijbbmb.20160101.15
AB  - A new series of Mn(II), Cu(II) and Zn(II) complexes with the two ligands were prepared and spectroscopic method and elemental analysis verified their structures. The first ligand L1 is flavylium salt and the second L2 is a Flavon. Reaction between transition metal salts and the ligands have synthesized two groups of new metal complexes. These complexes have been identified by available spectroscopic tools (UV-visible and IR) the C.H.N results confirmed the proposed structures. The experimental data disclosed that the complexes were coordinated by 6-the coordinate with mono-and bidentate ligands forming octahedral structure, in which L2 acts as monodentate and L1, L2 as bidentate ligands. The metal linked with L1 through the oxygen in ortho position in ring B, were as the linkage of the metal with L3 takes place through the oxygen of the carbonyl group. A theoretical treatment of the formation of complexes in the gas phase was studied, this was done using the HYPERCHEM-6 program for the Molecular mechanics and Semi-empirical calculations. The antimicrobial activity of the ligand and its metal complexes were studied against the following strains of microorganism: Staphylococcus aureus and Escherichia coli by the well diffusion method. Metal complexes showed enhanced antimicrobial activity compared with that of the free ligand.
VL  - 1
IS  - 1
ER  -

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Author Information

Omar H. Al-Obaidi

Chemistry Department, Education College for Women, Al-Anbar University, Ramadi, Iraq

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APA Style

Omar H. Al-Obaidi. (2016). Synthesis, Characterization, Theoretical and Antimicrobial Evaluation of New Mn(II), Cu(II) and Zn(II) Complexes of Flavylium Salt. International Journal of Biochemistry, Biophysics & Molecular Biology, 1(1), 31-35. https://doi.org/10.11648/j.ijbbmb.20160101.15

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ACS Style

Omar H. Al-Obaidi. Synthesis, Characterization, Theoretical and Antimicrobial Evaluation of New Mn(II), Cu(II) and Zn(II) Complexes of Flavylium Salt. Int. J. Biochem. Biophys. Mol. Biol. 2016, 1(1), 31-35. doi: 10.11648/j.ijbbmb.20160101.15

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AMA Style

Omar H. Al-Obaidi. Synthesis, Characterization, Theoretical and Antimicrobial Evaluation of New Mn(II), Cu(II) and Zn(II) Complexes of Flavylium Salt. Int J Biochem Biophys Mol Biol. 2016;1(1):31-35. doi: 10.11648/j.ijbbmb.20160101.15

Copy | Download

@article{10.11648/j.ijbbmb.20160101.15,
  author = {Omar H. Al-Obaidi},
  title = {Synthesis, Characterization, Theoretical and Antimicrobial Evaluation of New Mn(II), Cu(II) and Zn(II) Complexes of Flavylium Salt},
  journal = {International Journal of Biochemistry, Biophysics & Molecular Biology},
  volume = {1},
  number = {1},
  pages = {31-35},
  doi = {10.11648/j.ijbbmb.20160101.15},
  url = {https://doi.org/10.11648/j.ijbbmb.20160101.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbbmb.20160101.15},
  abstract = {A new series of Mn(II), Cu(II) and Zn(II) complexes with the two ligands were prepared and spectroscopic method and elemental analysis verified their structures. The first ligand L1 is flavylium salt and the second L2 is a Flavon. Reaction between transition metal salts and the ligands have synthesized two groups of new metal complexes. These complexes have been identified by available spectroscopic tools (UV-visible and IR) the C.H.N results confirmed the proposed structures. The experimental data disclosed that the complexes were coordinated by 6-the coordinate with mono-and bidentate ligands forming octahedral structure, in which L2 acts as monodentate and L1, L2 as bidentate ligands. The metal linked with L1 through the oxygen in ortho position in ring B, were as the linkage of the metal with L3 takes place through the oxygen of the carbonyl group. A theoretical treatment of the formation of complexes in the gas phase was studied, this was done using the HYPERCHEM-6 program for the Molecular mechanics and Semi-empirical calculations. The antimicrobial activity of the ligand and its metal complexes were studied against the following strains of microorganism: Staphylococcus aureus and Escherichia coli by the well diffusion method. Metal complexes showed enhanced antimicrobial activity compared with that of the free ligand.},
 year = {2016}
}

Copy | Download

TY  - JOUR
T1  - Synthesis, Characterization, Theoretical and Antimicrobial Evaluation of New Mn(II), Cu(II) and Zn(II) Complexes of Flavylium Salt
AU  - Omar H. Al-Obaidi
Y1  - 2016/10/26
PY  - 2016
N1  - https://doi.org/10.11648/j.ijbbmb.20160101.15
DO  - 10.11648/j.ijbbmb.20160101.15
T2  - International Journal of Biochemistry, Biophysics & Molecular Biology
JF  - International Journal of Biochemistry, Biophysics & Molecular Biology
JO  - International Journal of Biochemistry, Biophysics & Molecular Biology
SP  - 31
EP  - 35
PB  - Science Publishing Group
SN  - 2575-5862
UR  - https://doi.org/10.11648/j.ijbbmb.20160101.15
AB  - A new series of Mn(II), Cu(II) and Zn(II) complexes with the two ligands were prepared and spectroscopic method and elemental analysis verified their structures. The first ligand L1 is flavylium salt and the second L2 is a Flavon. Reaction between transition metal salts and the ligands have synthesized two groups of new metal complexes. These complexes have been identified by available spectroscopic tools (UV-visible and IR) the C.H.N results confirmed the proposed structures. The experimental data disclosed that the complexes were coordinated by 6-the coordinate with mono-and bidentate ligands forming octahedral structure, in which L2 acts as monodentate and L1, L2 as bidentate ligands. The metal linked with L1 through the oxygen in ortho position in ring B, were as the linkage of the metal with L3 takes place through the oxygen of the carbonyl group. A theoretical treatment of the formation of complexes in the gas phase was studied, this was done using the HYPERCHEM-6 program for the Molecular mechanics and Semi-empirical calculations. The antimicrobial activity of the ligand and its metal complexes were studied against the following strains of microorganism: Staphylococcus aureus and Escherichia coli by the well diffusion method. Metal complexes showed enhanced antimicrobial activity compared with that of the free ligand.
VL  - 1
IS  - 1
ER  -

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