Mormodica charantia is a plant of the Cucurbitaceae family known as bitter melon, karela, and pare. It grows in tropical areas of the Amazon, Asia, South America India, East Africa and Nigeria. It’s used traditionally as both food and medicine. Thisresearch showed the phytochemical and antimicrobial effects on the green synthesis of silver nanoparticles from Mormodica charantia. The phytochemical screening of the leaf extracts and the antimicrobial effect of Mormodica charantiawere studied. The aqueous extract of the plants was prepared from the leaves of the plant for the green synthesis of the silver nanoparticles. The phytochemical screening of the leaf extracts and the antimicrobial analysis were also carried out. The synthesized silver nanoparticles were characterized using Fourier Transmission Infrared Spectroscopy (FTIR). This study showed that Mormodica charantia inhibits the growth of E. coli but, has high inhibitory effect on the growth of fungi, Aspergillus niger, Aspergillus flavus, Aspergillus fumigatus, Fusarium solani and Candida albican tested. This suggests that these plants can be used for the treatment of fungi related diseases. The phytochemical screening results of the plants studied showed that they are good sources of alkaloids, flavonoids, saponins, terpenoids etc. which can be used in pharmacology. The FTIR results of the silver nanoparticles showed only a noticeable difference in the spectra of (Mormodica charantia) and (Mormodica charantia-AgNPs) in that the band 1327 cm-1 present in (Mormodica charantia) disappeared in (Mormodica charantia-AgNPs) and the band at 1593 cm-1 was observed in (Mormodica charantia-AgNPs) spectra. The band at 1593cm-1 in the as-synthesized (Mormodica charantia-AgNPs) suggested possible coordination of the (Mormodica charantia-AgNPs) with carboxylate ions formed during the reduction. FTIR spectra analysis confirmed conversion of Ag+ ions to AgNPs (Ag+ to Ag0) to reduction by capping material of plant extract.
| Published in | American Journal of Nano Research and Applications (Volume 9, Issue 3) |
| DOI | 10.11648/j.nano.20210903.11 |
| Page(s) | 16-24 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Phytochemical Constituents, Antimicrobial Activity, Mormodica charantia, Methanolic Extracts, Silver Nano Particles, FTIR and Green Synthesis
| [1] | Ahmad, Nesar., Noorul, Hasan., Zeeshan, Ahmad., Mohd, Zishan., Siekh, Zohrameena (2016): faculty of pharmacy, Integral University, Lucknow. Indian 226026. |
| [2] | Alves Eliana., Liliana Costa., Carla, M. B., Carvalho., Joao, P. C., Tome., Maria, A., Faustino (2009): BMC microbiology 9: (1) 70. |
| [3] | Andrews, G. P., Hromockyi, A. E., Coker, C, and Maurelli, A. T (2005): Two novel virulence loci. |
| [4] | Anesini, E., Perez, C, (1993): Screening of plants used in Argentine folk medicine forantimicrobial activity. Journal Ethnopharmacology. 3: 119-128. |
| [5] | Cefalu, W. T., Ye, J., Wang, Z. Q (2008): Efficacy of dietary supplementation with botanicals on carbohydrate metabolism in humans. Endocrine, Metabolic & Immune disorders Drug Targets 8: 78-81. |
| [6] | El- Olemy, M. M., Farid, J. A., Abdel-Fattah, A. A (1994): Ethanol Extract of P. stratiotes: NISEB Journal 1: (1) 51-59. |
| [7] | Ellof, J. N (1998): which extract should be used for the screening and isolation ofantimicrobial components from plants. Journal Ethnopharmacology 60: 1-6. |
| [8] | Hagerman, A. E., Zhao, Y., Johnson, S (1997): Methods of determination of condensedand hydrolysable tannins. Chapter 12 ofAnt- nutrients and phytochemicals in food. 209-222. |
| [9] | Harbone, J. B (1983): Phytochemical Methods. Chapman & Hall, London, 288. |
| [10] | Harborne, A. J. (1998): Springer science & business media. |
| [11] | Ibrahim, M. Abu-Reidah., Rana, M. Jamous., Mohammed, S. Ali-shtayeh (2014): JordanJournal of Biological Sciences 7: (4). |
| [12] | Jansen, A. M., Cheffer, J. J. C., Svendsen, A. B (1987): Antimicrobial activity of essential oils: a 1976-1986 literature review of aspects of test methods. Planta Medical 40: 395-398. |
| [13] | Jha, A., Prasad, K., Kulkarni, A. R (2009): "Plant system: nature's nanofactory". Colloids andSurfaces B. Bio interfaces journal 73: 219-223. |
| [14] | Leelaprakash., G. J., Rose C., Gowtham B. M., Javvaji P. K., and Prasad. S. A. (2011): Invitroantimicrobial and antioxidant activity of Momordica charantia leaves. Pharmacophore: 2 (4) 244-252. |
| [15] | Mada, S. B., Garba, A., Mohammad, H. A., Mohammad, A., Olagunji, A. (2013): Antimicrobial activity and phytochemical screening of aqueous and ethanol extracts of Momordicacharantia L. leaves. Journal of Medicinal Plants Research 6 (4): 566-573. |
| [16] | Mehrdad, Khatami., Shahram, Pourseyedi., Mansour, Khatami., Hadi, Hamidi., Mehranz, Zaeifi., and Lida, Soltani. (2015): Bio- resources and Bioprocessing 2: 19. |
| [17] | Mizushima, Y., and Kobayashi, M. (1968): Interaction of anti-inflammatory drugs with serum proteins, especially with some biologically active proteins. Journal of Pharmacy Pharmacological 20: 169- 173. |
| [18] | Muroi, H., Kubo, I. (1996): Antibacterial activity of anacardic acids and totarol, alone and in combination with methicillin, against methicillin-resistant Staphylococcus aureus. Journal of Applied Bacteriology 80: 387-394. |
| [19] | Nascimento, S. C., Chiappeta, A., Lima, R. M. O. C. (1990): Antimicrobial and cytotoxic activities in plants from Pernambuco, Brazil. Fitoterapia 61: 353-355. |
| [20] | Orgea, L. N., Efiom, O. O., Okwute, S. K (2013): Phytochemicals, antimicrobial and free radical scavenging activities of Mormodica charantia Linn (Palisota Reichb) seeds. African Journal of Pure and Applied Chemistry 7 (12): 405-409. |
| [21] | Parasharu, S. A (2009): “Bioinspired Synthesis of Silver Nanoparticles”. Digest Journal of Nanomaterials and Biostructures 4: 159-166. |
| [22] | Raman, A., Lau C. (1996): Anti-diabetic properties and phytochemistry of Mormodica charantia L. Phytome 349-62. |
| [23] | Ramteke., Charusheela., Tapan., Chakrabarti., Bijaya., Ketan, Sarangi., Ram-Avatar Pandey (2013): Journal of Chemistry. |
| [24] | Sakat, S., Juvekar A. R., and Gambhire, M. N. (2010): In vitro antioxidant and anti- inflammatory activity of methanol extract of Oxalis corniculata Linn. International Journal of Pharmacy and Pharmacological Sciences 2 (1): 146-155. |
| [25] | Salem, W. M., Haridy, M., Sayed, W. F., Hassan, N. H (2014): Antibacterial activity of silver nanoparticles synthesized from latex and leaf extract of Ficussycomorus, Industrial Cropsand Products. Science Direct 62: 228–234. |
| [26] | Santos, P. R. V., Oliveira, A. C. X., Tomassini, T. C. B (1995): Controlemicrobiógico deprodutosfitoterápicos. Rev. Farm. Bioquím 31: 35-38. |
| [27] | Saxena, G., McCutcheon, A. R., Farmer, S., Towers, G. H. N., Hancock, R. E. W (1994): antimicrobial constituents of Rhusglabra. Journal of Ethnopharmacology 42, 95-99. |
| [28] | Zhang, Q. C (1992): Preliminary report on the use of M. charantia extracted by HIV patients. Journal Naturopathic medicine 3: 65-69. |
APA Style
Janet Titilayo Bamgbose, Ezekiel Gbadebo Adeyeni, Adedibu Clement Tella, Princess Temitope Oyelakun. (2021). Green Synthesis of Silver Nanoparticles Using Leaf Extract Mormodica charantia: Phytochemical and Antimicrobial Activities. American Journal of Nano Research and Applications, 9(3), 16-24. https://doi.org/10.11648/j.nano.20210903.11
ACS Style
Janet Titilayo Bamgbose; Ezekiel Gbadebo Adeyeni; Adedibu Clement Tella; Princess Temitope Oyelakun. Green Synthesis of Silver Nanoparticles Using Leaf Extract Mormodica charantia: Phytochemical and Antimicrobial Activities. Am. J. Nano Res. Appl. 2021, 9(3), 16-24. doi: 10.11648/j.nano.20210903.11
AMA Style
Janet Titilayo Bamgbose, Ezekiel Gbadebo Adeyeni, Adedibu Clement Tella, Princess Temitope Oyelakun. Green Synthesis of Silver Nanoparticles Using Leaf Extract Mormodica charantia: Phytochemical and Antimicrobial Activities. Am J Nano Res Appl. 2021;9(3):16-24. doi: 10.11648/j.nano.20210903.11
Share This Article
Twitter
Linked In
Facebook
Copy
Download@article{10.11648/j.nano.20210903.11,
author = {Janet Titilayo Bamgbose and Ezekiel Gbadebo Adeyeni and Adedibu Clement Tella and Princess Temitope Oyelakun},
title = {Green Synthesis of Silver Nanoparticles Using Leaf Extract Mormodica charantia: Phytochemical and Antimicrobial Activities},
journal = {American Journal of Nano Research and Applications},
volume = {9},
number = {3},
pages = {16-24},
doi = {10.11648/j.nano.20210903.11},
url = {https://doi.org/10.11648/j.nano.20210903.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.nano.20210903.11},
abstract = {Mormodica charantia is a plant of the Cucurbitaceae family known as bitter melon, karela, and pare. It grows in tropical areas of the Amazon, Asia, South America India, East Africa and Nigeria. It’s used traditionally as both food and medicine. Thisresearch showed the phytochemical and antimicrobial effects on the green synthesis of silver nanoparticles from Mormodica charantia. The phytochemical screening of the leaf extracts and the antimicrobial effect of Mormodica charantiawere studied. The aqueous extract of the plants was prepared from the leaves of the plant for the green synthesis of the silver nanoparticles. The phytochemical screening of the leaf extracts and the antimicrobial analysis were also carried out. The synthesized silver nanoparticles were characterized using Fourier Transmission Infrared Spectroscopy (FTIR). This study showed that Mormodica charantia inhibits the growth of E. coli but, has high inhibitory effect on the growth of fungi, Aspergillus niger, Aspergillus flavus, Aspergillus fumigatus, Fusarium solani and Candida albican tested. This suggests that these plants can be used for the treatment of fungi related diseases. The phytochemical screening results of the plants studied showed that they are good sources of alkaloids, flavonoids, saponins, terpenoids etc. which can be used in pharmacology. The FTIR results of the silver nanoparticles showed only a noticeable difference in the spectra of (Mormodica charantia) and (Mormodica charantia-AgNPs) in that the band 1327 cm-1 present in (Mormodica charantia) disappeared in (Mormodica charantia-AgNPs) and the band at 1593 cm-1 was observed in (Mormodica charantia-AgNPs) spectra. The band at 1593cm-1 in the as-synthesized (Mormodica charantia-AgNPs) suggested possible coordination of the (Mormodica charantia-AgNPs) with carboxylate ions formed during the reduction. FTIR spectra analysis confirmed conversion of Ag+ ions to AgNPs (Ag+ to Ag0) to reduction by capping material of plant extract.},
year = {2021}
}
TY - JOUR T1 - Green Synthesis of Silver Nanoparticles Using Leaf Extract Mormodica charantia: Phytochemical and Antimicrobial Activities AU - Janet Titilayo Bamgbose AU - Ezekiel Gbadebo Adeyeni AU - Adedibu Clement Tella AU - Princess Temitope Oyelakun Y1 - 2021/11/10 PY - 2021 N1 - https://doi.org/10.11648/j.nano.20210903.11 DO - 10.11648/j.nano.20210903.11 T2 - American Journal of Nano Research and Applications JF - American Journal of Nano Research and Applications JO - American Journal of Nano Research and Applications SP - 16 EP - 24 PB - Science Publishing Group SN - 2575-3738 UR - https://doi.org/10.11648/j.nano.20210903.11 AB - Mormodica charantia is a plant of the Cucurbitaceae family known as bitter melon, karela, and pare. It grows in tropical areas of the Amazon, Asia, South America India, East Africa and Nigeria. It’s used traditionally as both food and medicine. Thisresearch showed the phytochemical and antimicrobial effects on the green synthesis of silver nanoparticles from Mormodica charantia. The phytochemical screening of the leaf extracts and the antimicrobial effect of Mormodica charantiawere studied. The aqueous extract of the plants was prepared from the leaves of the plant for the green synthesis of the silver nanoparticles. The phytochemical screening of the leaf extracts and the antimicrobial analysis were also carried out. The synthesized silver nanoparticles were characterized using Fourier Transmission Infrared Spectroscopy (FTIR). This study showed that Mormodica charantia inhibits the growth of E. coli but, has high inhibitory effect on the growth of fungi, Aspergillus niger, Aspergillus flavus, Aspergillus fumigatus, Fusarium solani and Candida albican tested. This suggests that these plants can be used for the treatment of fungi related diseases. The phytochemical screening results of the plants studied showed that they are good sources of alkaloids, flavonoids, saponins, terpenoids etc. which can be used in pharmacology. The FTIR results of the silver nanoparticles showed only a noticeable difference in the spectra of (Mormodica charantia) and (Mormodica charantia-AgNPs) in that the band 1327 cm-1 present in (Mormodica charantia) disappeared in (Mormodica charantia-AgNPs) and the band at 1593 cm-1 was observed in (Mormodica charantia-AgNPs) spectra. The band at 1593cm-1 in the as-synthesized (Mormodica charantia-AgNPs) suggested possible coordination of the (Mormodica charantia-AgNPs) with carboxylate ions formed during the reduction. FTIR spectra analysis confirmed conversion of Ag+ ions to AgNPs (Ag+ to Ag0) to reduction by capping material of plant extract. VL - 9 IS - 3 ER -
Information
Email: