The need for efficient plant-based remedies is becoming acknowledged across the world as the incidence of infectious diseases rises. Essential oils have been actively studied in the research for plant-derived biomolecules that can substitute synthetic medications and, to some extent, eliminate or lessen their side effects. The goal of this study was to explore the presence of phytochemicals in neroli essential oil as well as its many therapeutic properties. We aimed to present a thorough viewpoint on researching essential oil extracted from the bloom of the bitter orange tree as a suitable replacement for synthetic counterparts. The various components present in the essential oil were identified using GC-MS analysis. The oil's antimicrobial properties were tested against a variety of fungal strains. The antioxidant potential was assessed using the DPPH (2,2-diphenyl-1-picrylhydrazy) reagent in a free radical scavenging experiment. The oil exhibited a variable degree of anti-microbial nature against the bacterial and fungal strains. Furthermore, the antimalarial and antituberculosis property was also evaluated against Plasmodium falciparum and Mycobacterium tuberculosis respectively. Finally, a study for determining the cytotoxicity activity of the oil was studied on the Chinese Hamster Ovary (CHO) cell line. The study's findings revealed that neroli essential oil has natural components that can be used to cure a variety of ailments.
| Published in | International Journal of Pharmacy and Chemistry (Volume 8, Issue 3) |
| DOI | 10.11648/j.ijpc.20220803.11 |
| Page(s) | 24-34 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Anti-microbial, Anti-malarial, Anti-tuberculosis, Antioxidant, Cytotoxicity, DNA Barcoding, GC-MS
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APA Style
Vikas Jha, Aneesh Risbud, Sankalp Kasbe, Shreya Thube, Geetika Preman, et al. (2022). GC–MS Analysis and Investigation of Bioactive Potential of Essential Oil from Citrus aurantium var. amara. International Journal of Pharmacy and Chemistry, 8(3), 24-34. https://doi.org/10.11648/j.ijpc.20220803.11
ACS Style
Vikas Jha; Aneesh Risbud; Sankalp Kasbe; Shreya Thube; Geetika Preman, et al. GC–MS Analysis and Investigation of Bioactive Potential of Essential Oil from Citrus aurantium var. amara. Int. J. Pharm. Chem. 2022, 8(3), 24-34. doi: 10.11648/j.ijpc.20220803.11
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Download@article{10.11648/j.ijpc.20220803.11,
author = {Vikas Jha and Aneesh Risbud and Sankalp Kasbe and Shreya Thube and Geetika Preman and Sathi Maiti and Himadri Yadav and Farheen Khan and Fatimabi Shaikh and Tisha Jain},
title = {GC–MS Analysis and Investigation of Bioactive Potential of Essential Oil from Citrus aurantium var. amara},
journal = {International Journal of Pharmacy and Chemistry},
volume = {8},
number = {3},
pages = {24-34},
doi = {10.11648/j.ijpc.20220803.11},
url = {https://doi.org/10.11648/j.ijpc.20220803.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijpc.20220803.11},
abstract = {The need for efficient plant-based remedies is becoming acknowledged across the world as the incidence of infectious diseases rises. Essential oils have been actively studied in the research for plant-derived biomolecules that can substitute synthetic medications and, to some extent, eliminate or lessen their side effects. The goal of this study was to explore the presence of phytochemicals in neroli essential oil as well as its many therapeutic properties. We aimed to present a thorough viewpoint on researching essential oil extracted from the bloom of the bitter orange tree as a suitable replacement for synthetic counterparts. The various components present in the essential oil were identified using GC-MS analysis. The oil's antimicrobial properties were tested against a variety of fungal strains. The antioxidant potential was assessed using the DPPH (2,2-diphenyl-1-picrylhydrazy) reagent in a free radical scavenging experiment. The oil exhibited a variable degree of anti-microbial nature against the bacterial and fungal strains. Furthermore, the antimalarial and antituberculosis property was also evaluated against Plasmodium falciparum and Mycobacterium tuberculosis respectively. Finally, a study for determining the cytotoxicity activity of the oil was studied on the Chinese Hamster Ovary (CHO) cell line. The study's findings revealed that neroli essential oil has natural components that can be used to cure a variety of ailments.},
year = {2022}
}
TY - JOUR T1 - GC–MS Analysis and Investigation of Bioactive Potential of Essential Oil from Citrus aurantium var. amara AU - Vikas Jha AU - Aneesh Risbud AU - Sankalp Kasbe AU - Shreya Thube AU - Geetika Preman AU - Sathi Maiti AU - Himadri Yadav AU - Farheen Khan AU - Fatimabi Shaikh AU - Tisha Jain Y1 - 2022/06/30 PY - 2022 N1 - https://doi.org/10.11648/j.ijpc.20220803.11 DO - 10.11648/j.ijpc.20220803.11 T2 - International Journal of Pharmacy and Chemistry JF - International Journal of Pharmacy and Chemistry JO - International Journal of Pharmacy and Chemistry SP - 24 EP - 34 PB - Science Publishing Group SN - 2575-5749 UR - https://doi.org/10.11648/j.ijpc.20220803.11 AB - The need for efficient plant-based remedies is becoming acknowledged across the world as the incidence of infectious diseases rises. Essential oils have been actively studied in the research for plant-derived biomolecules that can substitute synthetic medications and, to some extent, eliminate or lessen their side effects. The goal of this study was to explore the presence of phytochemicals in neroli essential oil as well as its many therapeutic properties. We aimed to present a thorough viewpoint on researching essential oil extracted from the bloom of the bitter orange tree as a suitable replacement for synthetic counterparts. The various components present in the essential oil were identified using GC-MS analysis. The oil's antimicrobial properties were tested against a variety of fungal strains. The antioxidant potential was assessed using the DPPH (2,2-diphenyl-1-picrylhydrazy) reagent in a free radical scavenging experiment. The oil exhibited a variable degree of anti-microbial nature against the bacterial and fungal strains. Furthermore, the antimalarial and antituberculosis property was also evaluated against Plasmodium falciparum and Mycobacterium tuberculosis respectively. Finally, a study for determining the cytotoxicity activity of the oil was studied on the Chinese Hamster Ovary (CHO) cell line. The study's findings revealed that neroli essential oil has natural components that can be used to cure a variety of ailments. VL - 8 IS - 3 ER -
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