Brain Metastases in a Patient with Ovarian Cancer

Kantenga Dieu Merci Kabulo; Patrice Nday Ntenga; Nathaniel Hurunangoni Zimani; Kazadi Kaluile Ntenga Kalangu; Rudo Makunike Mutasa

doi:doi:10.11648/j.ijnpt.20170306.12

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Brain Metastases in a Patient with Ovarian Cancer

Kantenga Dieu Merci Kabulo, Patrice Nday Ntenga, Nathaniel Hurunangoni Zimani, Kazadi Kaluile Ntenga Kalangu, Rudo Makunike Mutasa

Received: 22 August 2017 Accepted: 4 September 2017 Published: 18 December 2017

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Abstract

Brain metastases are associated with a poor prognosis. Depending on the patient’s age, functional status, extent of systemic disease, and number of metastases. We report a case of 22-year-old female who presented with 2 months history of headache and vomiting and 1 day history of not communicating, neck stiffness, and generalized body weakness. Patient has been unwell for 2 months after she had collapsed at school 2 months prior complaining of severe headache, she allegedly stroked one month prior with left sided weakness. No history of trauma and seizures but had history of falling and remaining unconscious for unspecified period of time. No history of chronic illness and no family history of malignancies. Brain CT scan and MRI documented multiple lobulated irregularly enhancing brain parenchymal mass lesions of variable sizes, patient was taken to theatre and burr hole for brain tumor biopsy was done and specimen taken for histology which confirmed metastatic carcinoma and the tumor immunoreacted negatively to TTF1 and positively to CK7. Treatment of brain metastasis has evolved over the years from WBRT only for most patients to multimodal therapy including surgical resection, if feasible, followed by Whole brain Radiotherapy (WBRT) and/or chemotherapy.

DOI	10.11648/j.ijnpt.20170306.12
Published in	International Journal of Neurologic Physical Therapy (Volume 3, Issue 6, December 2017)
Page(s)	54-58
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Brain Metastases, Ovarian Cancer, Wholebrain Radiotherapy

References

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APA Style

Kantenga Dieu Merci Kabulo, Patrice Nday Ntenga, Nathaniel Hurunangoni Zimani, Kazadi Kaluile Ntenga Kalangu, Rudo Makunike Mutasa. (2017). Brain Metastases in a Patient with Ovarian Cancer. International Journal of Neurologic Physical Therapy, 3(6), 54-58. https://doi.org/10.11648/j.ijnpt.20170306.12

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ACS Style

Kantenga Dieu Merci Kabulo; Patrice Nday Ntenga; Nathaniel Hurunangoni Zimani; Kazadi Kaluile Ntenga Kalangu; Rudo Makunike Mutasa. Brain Metastases in a Patient with Ovarian Cancer. Int. J. Neurol. Phys. Ther. 2017, 3(6), 54-58. doi: 10.11648/j.ijnpt.20170306.12

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AMA Style

Kantenga Dieu Merci Kabulo, Patrice Nday Ntenga, Nathaniel Hurunangoni Zimani, Kazadi Kaluile Ntenga Kalangu, Rudo Makunike Mutasa. Brain Metastases in a Patient with Ovarian Cancer. Int J Neurol Phys Ther. 2017;3(6):54-58. doi: 10.11648/j.ijnpt.20170306.12

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@article{10.11648/j.ijnpt.20170306.12,
  author = {Kantenga Dieu Merci Kabulo and Patrice Nday Ntenga and Nathaniel Hurunangoni Zimani and Kazadi Kaluile Ntenga Kalangu and Rudo Makunike Mutasa},
  title = {Brain Metastases in a Patient with Ovarian Cancer},
  journal = {International Journal of Neurologic Physical Therapy},
  volume = {3},
  number = {6},
  pages = {54-58},
  doi = {10.11648/j.ijnpt.20170306.12},
  url = {https://doi.org/10.11648/j.ijnpt.20170306.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijnpt.20170306.12},
  abstract = {Brain metastases are associated with a poor prognosis. Depending on the patient’s age, functional status, extent of systemic disease, and number of metastases. We report a case of 22-year-old female who presented with 2 months history of headache and vomiting and 1 day history of not communicating, neck stiffness, and generalized body weakness. Patient has been unwell for 2 months after she had collapsed at school 2 months prior complaining of severe headache, she allegedly stroked one month prior with left sided weakness. No history of trauma and seizures but had history of falling and remaining unconscious for unspecified period of time. No history of chronic illness and no family history of malignancies. Brain CT scan and MRI documented multiple lobulated irregularly enhancing brain parenchymal mass lesions of variable sizes, patient was taken to theatre and burr hole for brain tumor biopsy was done and specimen taken for histology which confirmed metastatic carcinoma and the tumor immunoreacted negatively to TTF1 and positively to CK7. Treatment of brain metastasis has evolved over the years from WBRT only for most patients to multimodal therapy including surgical resection, if feasible, followed by Whole brain Radiotherapy (WBRT) and/or chemotherapy.},
 year = {2017}
}

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TY  - JOUR
T1  - Brain Metastases in a Patient with Ovarian Cancer
AU  - Kantenga Dieu Merci Kabulo
AU  - Patrice Nday Ntenga
AU  - Nathaniel Hurunangoni Zimani
AU  - Kazadi Kaluile Ntenga Kalangu
AU  - Rudo Makunike Mutasa
Y1  - 2017/12/18
PY  - 2017
N1  - https://doi.org/10.11648/j.ijnpt.20170306.12
DO  - 10.11648/j.ijnpt.20170306.12
T2  - International Journal of Neurologic Physical Therapy
JF  - International Journal of Neurologic Physical Therapy
JO  - International Journal of Neurologic Physical Therapy
SP  - 54
EP  - 58
PB  - Science Publishing Group
SN  - 2575-1778
UR  - https://doi.org/10.11648/j.ijnpt.20170306.12
AB  - Brain metastases are associated with a poor prognosis. Depending on the patient’s age, functional status, extent of systemic disease, and number of metastases. We report a case of 22-year-old female who presented with 2 months history of headache and vomiting and 1 day history of not communicating, neck stiffness, and generalized body weakness. Patient has been unwell for 2 months after she had collapsed at school 2 months prior complaining of severe headache, she allegedly stroked one month prior with left sided weakness. No history of trauma and seizures but had history of falling and remaining unconscious for unspecified period of time. No history of chronic illness and no family history of malignancies. Brain CT scan and MRI documented multiple lobulated irregularly enhancing brain parenchymal mass lesions of variable sizes, patient was taken to theatre and burr hole for brain tumor biopsy was done and specimen taken for histology which confirmed metastatic carcinoma and the tumor immunoreacted negatively to TTF1 and positively to CK7. Treatment of brain metastasis has evolved over the years from WBRT only for most patients to multimodal therapy including surgical resection, if feasible, followed by Whole brain Radiotherapy (WBRT) and/or chemotherapy.
VL  - 3
IS  - 6
ER  -

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Author Information

Kantenga Dieu Merci Kabulo

Department of Neurosurgery, University of Zimbabwe, Harare, Zimbabwe
Patrice Nday Ntenga

Neurological Clinic of the National Teaching Hospital-FANN, Dakar, Senegal
Nathaniel Hurunangoni Zimani

Department of Neurosurgery, University of Zimbabwe, Harare, Zimbabwe
Kazadi Kaluile Ntenga Kalangu

Department of Neurosurgery, University of Zimbabwe, Harare, Zimbabwe
Rudo Makunike Mutasa

Department of Pathology, University of Zimbabwe, Harare, Zimbabwe

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APA Style

Kantenga Dieu Merci Kabulo, Patrice Nday Ntenga, Nathaniel Hurunangoni Zimani, Kazadi Kaluile Ntenga Kalangu, Rudo Makunike Mutasa. (2017). Brain Metastases in a Patient with Ovarian Cancer. International Journal of Neurologic Physical Therapy, 3(6), 54-58. https://doi.org/10.11648/j.ijnpt.20170306.12

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ACS Style

Kantenga Dieu Merci Kabulo; Patrice Nday Ntenga; Nathaniel Hurunangoni Zimani; Kazadi Kaluile Ntenga Kalangu; Rudo Makunike Mutasa. Brain Metastases in a Patient with Ovarian Cancer. Int. J. Neurol. Phys. Ther. 2017, 3(6), 54-58. doi: 10.11648/j.ijnpt.20170306.12

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AMA Style

Kantenga Dieu Merci Kabulo, Patrice Nday Ntenga, Nathaniel Hurunangoni Zimani, Kazadi Kaluile Ntenga Kalangu, Rudo Makunike Mutasa. Brain Metastases in a Patient with Ovarian Cancer. Int J Neurol Phys Ther. 2017;3(6):54-58. doi: 10.11648/j.ijnpt.20170306.12

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@article{10.11648/j.ijnpt.20170306.12,
  author = {Kantenga Dieu Merci Kabulo and Patrice Nday Ntenga and Nathaniel Hurunangoni Zimani and Kazadi Kaluile Ntenga Kalangu and Rudo Makunike Mutasa},
  title = {Brain Metastases in a Patient with Ovarian Cancer},
  journal = {International Journal of Neurologic Physical Therapy},
  volume = {3},
  number = {6},
  pages = {54-58},
  doi = {10.11648/j.ijnpt.20170306.12},
  url = {https://doi.org/10.11648/j.ijnpt.20170306.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijnpt.20170306.12},
  abstract = {Brain metastases are associated with a poor prognosis. Depending on the patient’s age, functional status, extent of systemic disease, and number of metastases. We report a case of 22-year-old female who presented with 2 months history of headache and vomiting and 1 day history of not communicating, neck stiffness, and generalized body weakness. Patient has been unwell for 2 months after she had collapsed at school 2 months prior complaining of severe headache, she allegedly stroked one month prior with left sided weakness. No history of trauma and seizures but had history of falling and remaining unconscious for unspecified period of time. No history of chronic illness and no family history of malignancies. Brain CT scan and MRI documented multiple lobulated irregularly enhancing brain parenchymal mass lesions of variable sizes, patient was taken to theatre and burr hole for brain tumor biopsy was done and specimen taken for histology which confirmed metastatic carcinoma and the tumor immunoreacted negatively to TTF1 and positively to CK7. Treatment of brain metastasis has evolved over the years from WBRT only for most patients to multimodal therapy including surgical resection, if feasible, followed by Whole brain Radiotherapy (WBRT) and/or chemotherapy.},
 year = {2017}
}

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TY  - JOUR
T1  - Brain Metastases in a Patient with Ovarian Cancer
AU  - Kantenga Dieu Merci Kabulo
AU  - Patrice Nday Ntenga
AU  - Nathaniel Hurunangoni Zimani
AU  - Kazadi Kaluile Ntenga Kalangu
AU  - Rudo Makunike Mutasa
Y1  - 2017/12/18
PY  - 2017
N1  - https://doi.org/10.11648/j.ijnpt.20170306.12
DO  - 10.11648/j.ijnpt.20170306.12
T2  - International Journal of Neurologic Physical Therapy
JF  - International Journal of Neurologic Physical Therapy
JO  - International Journal of Neurologic Physical Therapy
SP  - 54
EP  - 58
PB  - Science Publishing Group
SN  - 2575-1778
UR  - https://doi.org/10.11648/j.ijnpt.20170306.12
AB  - Brain metastases are associated with a poor prognosis. Depending on the patient’s age, functional status, extent of systemic disease, and number of metastases. We report a case of 22-year-old female who presented with 2 months history of headache and vomiting and 1 day history of not communicating, neck stiffness, and generalized body weakness. Patient has been unwell for 2 months after she had collapsed at school 2 months prior complaining of severe headache, she allegedly stroked one month prior with left sided weakness. No history of trauma and seizures but had history of falling and remaining unconscious for unspecified period of time. No history of chronic illness and no family history of malignancies. Brain CT scan and MRI documented multiple lobulated irregularly enhancing brain parenchymal mass lesions of variable sizes, patient was taken to theatre and burr hole for brain tumor biopsy was done and specimen taken for histology which confirmed metastatic carcinoma and the tumor immunoreacted negatively to TTF1 and positively to CK7. Treatment of brain metastasis has evolved over the years from WBRT only for most patients to multimodal therapy including surgical resection, if feasible, followed by Whole brain Radiotherapy (WBRT) and/or chemotherapy.
VL  - 3
IS  - 6
ER  -

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