Central African Journal of Public Health

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Declaration of Blood Sugar Levels with Black Raw and Binahong Leaves in Mencit (Mus musululus)

Received: Dec. 18, 2019    Accepted: Jan. 04, 2020    Published: Jan. 13, 2020
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Abstract

Diabetes mellitus is a disease marked by an increase in blood sugar levels. At present many sufferers of Diabetes Mellitus whose blood sugar levels are not controlled so that it can cause complications. The purpose of this study was to reduce blood sugar levels with black onion extract and binahong leaf extract on mice (mus musculus). This study uses a Quasy Experimental design with One Group pre-posttest. Samples were taken A total of 32 mice consisted of 16 in the intervention group and the comparison intervention group. The independent variables in this study were black onion extract and binahong leaf extract, while the dependent variable was the blood sugar level of mice. Data were collected by observation sheets and analyzed using Kolmogorov-Smirnov and Independent sample T-tests. The results of this study showed that the difference between pre and post-reduction of black onion extract was 66.4 mg/dl and the difference between pre and post administration of binahong leaf extract was 66.2 mg/dl. While the analysis shows the value of p = value 0.985. The results of this study indicate that extracts of black garlic and binahong leaves are equally effective in reducing blood sugar levels and that there are no significant differences in reducing blood sugar levels in mice. Thus both the black onion extract and the binahong leaf are equally effective in reducing blood sugar levels.

DOI 10.11648/j.cajph.20200601.14
Published in Central African Journal of Public Health ( Volume 6, Issue 1, February 2020 )
Page(s) 18-22
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Diabetes Mellitus, Black Onion Extract, Binahong Leaves, Blood Sugar Level, Mice (Mus musculus)

References
[1] S. M. J. D. Amir, “Kadar gula darah sewaktu pada pasien Diabetes Melitus tipe 2 di Puskesmas Bahu Kota Menado,” J. e-Biomedik, vol. 3, no. 1, 2015.
[2] B. A. M. Flacka, “Blood pressure and the new ACC/AHA hypertension guidelines,” Trends Cardiovasc. Med., vol. 29, no. 3, 2019.
[3] Riset Kesehatan Dasar, Badan Penelitian dan Pengembangan Kesehatan. Jakarta: Kementrian Kesehatan RI, 2015.
[4] K. P. Supa Pengpid, “Utilization of traditional and complementary medicine in Indonesia: Results of a national survey in 2014–15,” Complement. Ther. Clin. Pract., vol. 33, pp. 156–163, 2018.
[5] M. Taufik Perwira Wicaksono, “Diabetes mellitus tipe II gula darah tidak terkontrol dengan komplikasi neuropati diabetikum,” Medula, vol. 1, no. 3, 2013.
[6] W. wiyono Indri Wirasuasty Makalalag, Adeanne Wullur, “Uji Ekstrak Daun Binahong ( Anredera cordifolia Steen.) Terhadap kadar Gula Darah Pada Tikus Putih Jantan Galur Wistar ( Rattus norvegicus) yang Diinduksi Sukrosa,” Pharmacon, vol. 2, no. 1, 2013.
[7] S. W. Jung, E. S., Park, S. H., Choi, E. K., Ryu, B. H., Park, B. H., Kim, D. S., Kim, Y. G., & Chae, “Reduction of blood lipid parameters by a 12-wk supplementation of aged black garlic: a randomized controlled trial. Nutrition,” Nutrition, vol. 30, no. 9, 2014.
[8] H. Y. Morteza Nasiri, Mohammad Abbasi, Zeynab Yousefi Khosroabadi, Hossien Saghafi, Fahimeh Hamzeei, Meysam Hosseini Amiri, “Short-term effects of massage with olive oil on the severity of uremic restless legs syndrome: A double-blind placebo-controlled trial,” Complement. Ther. Med., vol. 44, pp. 261–268, 2019.
[9] B.. Rizky, “White Dragon Fruit (Hylocereus undatus) Potential As Diabetes Mellitus Treatment,” Med. J. LAMPUNG Univ., vol. 4, no. 1, pp. 69–72, 2015.
[10] O. C. Kim, J. S., Kang, O. J., & Gweon, “Comparison of phenolic acids and flavonoids in black garlic at different thermal processing step,” J. Funct. Foods, vol. 5, no. 1, pp. 80–86, 2013.
[11] et al Anna R. Kahkoska, Scott Isom, Jasmin Divers, “The early natural history of albuminuria in young adults with youth-onset type 1 and type 2 diabetes,” J. Diabetes its, vol. 32, no. 12, pp. 1160–1168, 2018.
[12] W. Makalalag, I. W. Wullur, A. Adeanne dan Wiyono, “Uji Ekstrak Daun Binahong (Anredera cordifolia (Ten) Steenis) Terhadap Kadar Gula Darah Pada Tikus Putih Jantan Galur Wistar ( Rattus norvegicus) yang diinduksi Sukrosa,” J. Ilm. Farm., vol. 2, no. 1, 2013.
[13] L. C.-M. Flahive MW, Chuang Y-C, “The Multimedia Piers-Harris Children’s Self-Concept Scale 2: Its Psychometric Properties, Equivalence with the Paper-and-Pencil Version, and Respondent Preferences,” PLoS One, vol. 10, no. 8, pp. 1–13, 2015.
[14] Kementrian Republik Indonesia, Formularium Obat Herbal Asli Indonesia. Jakarta: EGC, 2011.
[15] A. G. Pittas, Saud Alzahrani, Jason Nelson, Steven F. Moss, Jessica K. Paulus, William C. Knowler, “H. pylori seroprevalence and risk of diabetes: An ancillary case–control study nested in the diabetes prevention program,” J. Diabetes Complications, vol. 31, no. 10, pp. 1515–1520, 2017.
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  • APA Style

    Eni Sumarliyah, Dede Nasrullah, Mahardika Putra Tri Utama. (2020). Declaration of Blood Sugar Levels with Black Raw and Binahong Leaves in Mencit (Mus musululus). Central African Journal of Public Health, 6(1), 18-22. https://doi.org/10.11648/j.cajph.20200601.14

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    ACS Style

    Eni Sumarliyah; Dede Nasrullah; Mahardika Putra Tri Utama. Declaration of Blood Sugar Levels with Black Raw and Binahong Leaves in Mencit (Mus musululus). Cent. Afr. J. Public Health 2020, 6(1), 18-22. doi: 10.11648/j.cajph.20200601.14

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    AMA Style

    Eni Sumarliyah, Dede Nasrullah, Mahardika Putra Tri Utama. Declaration of Blood Sugar Levels with Black Raw and Binahong Leaves in Mencit (Mus musululus). Cent Afr J Public Health. 2020;6(1):18-22. doi: 10.11648/j.cajph.20200601.14

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  • @article{10.11648/j.cajph.20200601.14,
      author = {Eni Sumarliyah and Dede Nasrullah and Mahardika Putra Tri Utama},
      title = {Declaration of Blood Sugar Levels with Black Raw and Binahong Leaves in Mencit (Mus musululus)},
      journal = {Central African Journal of Public Health},
      volume = {6},
      number = {1},
      pages = {18-22},
      doi = {10.11648/j.cajph.20200601.14},
      url = {https://doi.org/10.11648/j.cajph.20200601.14},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.cajph.20200601.14},
      abstract = {Diabetes mellitus is a disease marked by an increase in blood sugar levels. At present many sufferers of Diabetes Mellitus whose blood sugar levels are not controlled so that it can cause complications. The purpose of this study was to reduce blood sugar levels with black onion extract and binahong leaf extract on mice (mus musculus). This study uses a Quasy Experimental design with One Group pre-posttest. Samples were taken A total of 32 mice consisted of 16 in the intervention group and the comparison intervention group. The independent variables in this study were black onion extract and binahong leaf extract, while the dependent variable was the blood sugar level of mice. Data were collected by observation sheets and analyzed using Kolmogorov-Smirnov and Independent sample T-tests. The results of this study showed that the difference between pre and post-reduction of black onion extract was 66.4 mg/dl and the difference between pre and post administration of binahong leaf extract was 66.2 mg/dl. While the analysis shows the value of p = value 0.985. The results of this study indicate that extracts of black garlic and binahong leaves are equally effective in reducing blood sugar levels and that there are no significant differences in reducing blood sugar levels in mice. Thus both the black onion extract and the binahong leaf are equally effective in reducing blood sugar levels.},
     year = {2020}
    }
    

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  • TY  - JOUR
    T1  - Declaration of Blood Sugar Levels with Black Raw and Binahong Leaves in Mencit (Mus musululus)
    AU  - Eni Sumarliyah
    AU  - Dede Nasrullah
    AU  - Mahardika Putra Tri Utama
    Y1  - 2020/01/13
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    N1  - https://doi.org/10.11648/j.cajph.20200601.14
    DO  - 10.11648/j.cajph.20200601.14
    T2  - Central African Journal of Public Health
    JF  - Central African Journal of Public Health
    JO  - Central African Journal of Public Health
    SP  - 18
    EP  - 22
    PB  - Science Publishing Group
    SN  - 2575-5781
    UR  - https://doi.org/10.11648/j.cajph.20200601.14
    AB  - Diabetes mellitus is a disease marked by an increase in blood sugar levels. At present many sufferers of Diabetes Mellitus whose blood sugar levels are not controlled so that it can cause complications. The purpose of this study was to reduce blood sugar levels with black onion extract and binahong leaf extract on mice (mus musculus). This study uses a Quasy Experimental design with One Group pre-posttest. Samples were taken A total of 32 mice consisted of 16 in the intervention group and the comparison intervention group. The independent variables in this study were black onion extract and binahong leaf extract, while the dependent variable was the blood sugar level of mice. Data were collected by observation sheets and analyzed using Kolmogorov-Smirnov and Independent sample T-tests. The results of this study showed that the difference between pre and post-reduction of black onion extract was 66.4 mg/dl and the difference between pre and post administration of binahong leaf extract was 66.2 mg/dl. While the analysis shows the value of p = value 0.985. The results of this study indicate that extracts of black garlic and binahong leaves are equally effective in reducing blood sugar levels and that there are no significant differences in reducing blood sugar levels in mice. Thus both the black onion extract and the binahong leaf are equally effective in reducing blood sugar levels.
    VL  - 6
    IS  - 1
    ER  - 

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Author Information
  • Departement Nursing, Faculty Health of Science, University Muhammadiyah of Surabaya, Surabaya, Indonesia

  • Departement Nursing, Faculty Health of Science, University Muhammadiyah of Surabaya, Surabaya, Indonesia

  • Departement Nursing, Faculty Health of Science, University Muhammadiyah of Surabaya, Surabaya, Indonesia

  • Section