International Journal of Animal Science and Technology

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Microscopic Anatomy of Sertoli and Leydig Cells During Fetal Development in Baladi Rabbit

Received: Nov. 26, 2017    Accepted: Dec. 08, 2017    Published: Jan. 10, 2018
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Abstract

Fifty three baladi rabbit embryos and fetuses were used in this study. The results revealed that the testicular differentiation occurred with the formation of the testicular cords with their constituents, gonocytes and primitive Sertoli cells at the 18th day postconception. The Sertoli cells were increased in number from 20th day postconception onwards and they appeared as small sized cells with oval darker nuclei. The Leydig cells were demonstrated at the 20th day of gestation life as clusters of polyhedral large cells with strongly acidophilic finely granular cytoplasm and large, vesicular, spherical and eccentric nuclei. At 28th day postconception up to the full term rabbit fetus, the Leydig cells of the testis showed a marked reduction in size and number.

DOI 10.11648/j.ijast.20180201.11
Published in International Journal of Animal Science and Technology ( Volume 2, Issue 1, March 2018 )
Page(s) 1-5
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Microscopic Anatomy, Sertoli Cells, Leydig Cells, Fetus, Rabbit

References
[1] George, F. W. and J. D. Wilson (1979). The regulation of androgen and estrogen formation in fetal gonads. Annales de biologie animale, biochimie, biophysique, 19 (4B), 1297-1306.
[2] Nielsen, H. C. and J. S. Torday (1983). Anatomy of fetal rabbit gonads and the sexing of fetal rabbits. Laboratory Animals 17, 148-150.
[3] Diaz-Hernandez, V., A. Leon del Rio, M. Zamora, and H. Merchant- Larios (2008). Expression profiles of SRY and SOX9 in rabbit gonads: The classical model of mammalian sex differentiation. Sexual Development 2 (3), 152-166.
[4] Hayashi, T., Y. Kageyama, K. Ischizaka, K. Kihara, and H. Oshima (2002). Involvement of apoptosis in the control of Sertoli cells and pre-meiotic germ cell numbers in the developing rabbit testis. Andrologia 34 (1), 34-40.
[5] J. D. Bancroft and A. Gamble, “Theory and practice of histological” techniques. 6th Ed., Churchill- Livingstone, Edinburgh, London, Melbourne, New York: 2008.
[6] Jost, A., S. Perlman, and S. Magre (1985). The initial stages of testicular differentiation in the rabbit fetus. Archives d'anatomie microscopique et de morphologie experimentale 74 (1), 69-75.
[7] Allen, B. M, (1904). The embryonic development of the ovary and testis of the mammals. The American Journal of Anatomy 3 (2), 89-154.
[8] Wartenberg, H., I. Kinsky, C. Viebahn, and C. Schmolke (1991). Fine structural characteristics of testicular cord formation in the developing rabbit gonad. Journal of Electron Microscopy Technique 19 (2), 133- 157.
[9] Hoar, R. M. and I. W. Monie (1981). Comparative development of specific organ system. Developmental Toxicology, 13-33.
[10] El-Oksha, S. M., (1993). Developmental studies on the testis of rabbit. MSc Thesis, Faculty of Veterinary Medicine, Moshtohor, Zagazig University (Benha), Egypt.
[11] Gondos, B. and L. A. Conner (1973). Ultrastructure of developing germ cells in the foetal rabbit testis. American journal of Anatomy 136 (1), 23- 41. In.
[12] Konsowa, M. M., (1997). The development of the male genitalia of the rabbit with reference to its vasculature. PhD Thesis, Faculty of Veterinary Medicine, Zagazig University, Egypt.
[13] Bjerregaard, P., F. Bro-Rasmussen and T, Reumert (1974) Ultrastructure development of fetal rabbit testis. Zeitschrift Fur Zellforschung Und Mikroskopische Anatomie 147, 401-413.
[14] Mazher, K. M., (1997). Histological studies of the testis of the goat fetuses. MVSc Faculty of Veterinary Medicine, Cairo. University (Beni Suef Branch), Egypt.
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    Reda Mohamed, Zein Adam, Mohammed Gad, Khalid Mazher. (2018). Microscopic Anatomy of Sertoli and Leydig Cells During Fetal Development in Baladi Rabbit. International Journal of Animal Science and Technology, 2(1), 1-5. https://doi.org/10.11648/j.ijast.20180201.11

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    ACS Style

    Reda Mohamed; Zein Adam; Mohammed Gad; Khalid Mazher. Microscopic Anatomy of Sertoli and Leydig Cells During Fetal Development in Baladi Rabbit. Int. J. Anim. Sci. Technol. 2018, 2(1), 1-5. doi: 10.11648/j.ijast.20180201.11

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    AMA Style

    Reda Mohamed, Zein Adam, Mohammed Gad, Khalid Mazher. Microscopic Anatomy of Sertoli and Leydig Cells During Fetal Development in Baladi Rabbit. Int J Anim Sci Technol. 2018;2(1):1-5. doi: 10.11648/j.ijast.20180201.11

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  • @article{10.11648/j.ijast.20180201.11,
      author = {Reda Mohamed and Zein Adam and Mohammed Gad and Khalid Mazher},
      title = {Microscopic Anatomy of Sertoli and Leydig Cells During Fetal Development in Baladi Rabbit},
      journal = {International Journal of Animal Science and Technology},
      volume = {2},
      number = {1},
      pages = {1-5},
      doi = {10.11648/j.ijast.20180201.11},
      url = {https://doi.org/10.11648/j.ijast.20180201.11},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ijast.20180201.11},
      abstract = {Fifty three baladi rabbit embryos and fetuses were used in this study. The results revealed that the testicular differentiation occurred with the formation of the testicular cords with their constituents, gonocytes and primitive Sertoli cells at the 18th day postconception. The Sertoli cells were increased in number from 20th day postconception onwards and they appeared as small sized cells with oval darker nuclei. The Leydig cells were demonstrated at the 20th day of gestation life as clusters of polyhedral large cells with strongly acidophilic finely granular cytoplasm and large, vesicular, spherical and eccentric nuclei. At 28th day postconception up to the full term rabbit fetus, the Leydig cells of the testis showed a marked reduction in size and number.},
     year = {2018}
    }
    

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    AU  - Reda Mohamed
    AU  - Zein Adam
    AU  - Mohammed Gad
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    T2  - International Journal of Animal Science and Technology
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    JO  - International Journal of Animal Science and Technology
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    UR  - https://doi.org/10.11648/j.ijast.20180201.11
    AB  - Fifty three baladi rabbit embryos and fetuses were used in this study. The results revealed that the testicular differentiation occurred with the formation of the testicular cords with their constituents, gonocytes and primitive Sertoli cells at the 18th day postconception. The Sertoli cells were increased in number from 20th day postconception onwards and they appeared as small sized cells with oval darker nuclei. The Leydig cells were demonstrated at the 20th day of gestation life as clusters of polyhedral large cells with strongly acidophilic finely granular cytoplasm and large, vesicular, spherical and eccentric nuclei. At 28th day postconception up to the full term rabbit fetus, the Leydig cells of the testis showed a marked reduction in size and number.
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Author Information
  • Department of Basic Veterinary Sciences, School of Veterinary Medicine, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Republic of Trinidad and Tobago; Department of Anatomy and Embryology, Faculty of Veterinary Medicine, Beni Suef University, Beni Suef, Egypt

  • Department of Anatomy and Embryology, Faculty of Veterinary Medicine, Beni Suef University, Beni Suef, Egypt

  • Department of Anatomy and Embryology, Faculty of Veterinary Medicine, Beni Suef University, Beni Suef, Egypt

  • Department Cytology and Histology, Faculty of Veterinary Medicine, Beni Suef University, Beni Suef, Egypt

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