Premarital Sickle Cell Genetic Screening Knowledge, Attitude and Practice Compared Among Married and Unmarried Youths in Nigeria

Tajudeen Olusegun Rasheed; Wasiu Adebowale Afolabi; Rukayat Ololade Abdul Rasheed; Rasheedat Adenike Ajala

doi:doi:10.11648/j.wjph.20180303.12

| Peer-Reviewed

Premarital Sickle Cell Genetic Screening Knowledge, Attitude and Practice Compared Among Married and Unmarried Youths in Nigeria

Tajudeen Olusegun Rasheed, Wasiu Adebowale Afolabi, Rukayat Ololade Abdul Rasheed, Rasheedat Adenike Ajala

Published in World Journal of Public Health (Volume 3, Issue 3)

Received: 17 June 2018 Accepted: 9 July 2018 Published: 9 August 2018

Views: Downloads:

Download PDF

Share This Article

Twitter
Linked In
Facebook

Abstract

Premarital sickle cell genetic screening is a test that determines the genotype of the intending couple before marriage. As a result, counseling is given before and after the test. This study assessed and compared the level of knowledge, attitude and practices of premarital sickle cell screening among married and unmarried youths in Epe, Nigeria. A cross-sectional descriptive research design was used to examine 370 participants, using stratified sampling technique. Data were collected with an instrument and analyzed, stating the mean, frequency and standard deviation. Scores were built for knowledge, attitude and practice. Chi-square test with p < 0.05 was used to test the hypotheses. The study revealed that an association exists between knowledge and practice of premarital sickle cell genetic screening among unmarried (X² = 6.359, Cramer’s v=0.09, p=0.0116, df = 1) and married (X² = 12.9325, Cramer’s v=0.10, p=0.0003, df =1) youths. Similarly, an association exists between attitude and practices of premarital sickle cell genetic screening for unmarried youth (X² = 20.3077, p=0.0007, Cramer’s v=0.17, df = 1) but for married youths there was no association (X² = 0.0168, p = 0.8969, Cramer’s v=0.08, df = 1). Furthermore, finding revealed that 77% of the married participants did not have sickle cell genetic screening test before marriage, while 67% of the unmarried participants were not willing to carry out the test, due to fear of the unknown and stigma. Conclusively, the level of knowledge of the participants’ was good (70.06%), attitude was negative towards practices of premarital sickle cell genetic screening. Therefore, continuous health education that focuses on sickle cell genetic screening test could improve the practices among the youth to avert the associated morbidity and mortality.

Published in	World Journal of Public Health (Volume 3, Issue 3)
DOI	10.11648/j.wjph.20180303.12
Page(s)	76-82
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Premarital, Genetic Screening, Sickle Cell Disease, Youth, Nigeria

References

[1]	WHO. Sickle-cell disease and other hemoglobin disorders. 2016; 1-3. Retrieved from http://www.who.int/mediacentre/factsheets/fs308/en/
[2]	Genetic Learning Center. Genetic disorders. 2016; 1-7. Retrieved from http://www.learn-genetics_utah.edu/content/disorders
[3]	Saraf SL, Molokie RE, Nouraie M, Sable CA, Luchtman-Jones L. Differences in the clinical and genotypic presentation of sickle cell disease around the world. Pediatrics Respiratory Reviews. 2014; 15(1): 4-12.
[4]	Nnaji GA, Ezeagwuna DA, NnajiI JF, Osakwe JO, Nwigwe AC. Prevalence and pattern of sickle cell disease in premarital couples in Southeastern Nigeria. Nigerian J of Clinical Practice. 2013; 16(3): 309-314.
[5]	Chakravorty S, Williams TN. Sickle cell disease: a neglected chronic disease of increasing global health importance. Archives of Disease in Childhood. 2015; 100(1): 48-53.
[6]	Oyedele EA, Emmanuel A, Gaji LD, Ahure DOE. Awareness and acceptance of premarital genotype screening among youths in a Nigerian community. Internatl J of Medical and Health Research. 2015; 1(1): 17-21. Retrieved from http://discover.saemobilus.org/scholarlyjournalsbing?utm_source=bing%26utm_campaign=NTN-Scholarly_Journals-MB%26utm_device=c%26utm_medium=cpc%26utm_content=81157718894812%26utm_term=%2Binternational%20%2Bjournal%26utm_keymatch=p%26utm_adpostion={adpostion}%26utm_phone=833-539-4592
[7]	Anie KA, Akinyanju OO, Egunjobi FE. Psychosocial impact of sickle cell disorder: perspectives from a Nigerian setting. 2010: University press.
[8]	Ajazen I, Fishbein M. Understanding attitudes and predicting. Social Behavior. Eagle wood cliffs. 1980; New Jersey.
[9]	Alkindi M. Salha AR, AL-kend M. Knowledge and attitude of University Students towards Premarital Sickle Cell screening Program. Coman medical journal. 2012; 27(4): 291 – 296.
[10]	Krejcie RV, Morgan DW. Determining sample size for research activities. Educational and psychological measurement. 1970; 30: 607-610.
[11]	Omuemu VO, Obarisiagbon OE, Ogboghodo EO. Awareness and acceptability of premarital screening of sickle cell disease among undergraduate students of the University of Benin, Benin City, Edo State. J of Med. and Biomedical Research. 2013; 12(1): 91-104.
[12]	Durotoye IA, Salaudeen AG, Babatunde AS, Bosah EC. Knowledge and perception of sickle cell disease among senior secondary school students in Ilorin metropolis. The Tropical J of Health Sciences. 2013; 20(2): 1-7. Retrieved fromhttps://www.ajol.info/index.php/tjhc
[13]	Gbenol PK, Brisibe SF, Ordinioha B. Knowledge, attitude and uptake of premarital screening for the sickle trait among married couples in a semi urban community in South-South Nigeria. European J of Prev. Med. 2015; 3: 49-54. https://doi-org.ezp.waldenulibrary.org/10.11648/j.ejpm.20150303.13
[14]	Adewoyin AS. Management of sickle cell disease: a review for physician education in Nigeria (sub-saharan Africa). National Library of Medicine. Anemia. 2015; 791498.
[15]	Aneke J, Okocha C. Sickle cell disease genetic counseling and testing: A review Alternate title: Review Article. Archives of Med. and Health Sciences. 2016; 4(1): 50.
[16]	Nnodu OE. Interventions for the prevention of sickle cell disease at primary health care centres in Gwagwalada area council of the Federal Capital Territory, Nigeria. Cureus. 2014; 6(8): e194. doi:10. 7759/cureus. 194
[17]	Ogun GO, Ebili H, Kotila TR. Autopsy findings and pattern of mortality in Nigerian sickle cell disease patients. National Library of Medicine. The Pan African Medical J. 2014; 18: 30.
[18]	Grosse SD, Odame I, Atrash HK, Amendah DD, Piel FB. Sickle cell disease in Africa: A neglected cause of early childhood mortality. American J of Prev. Med. 2011; 41(6): Suppl 4, S398-S405.
[19]	Afolayan JA, Jolayemi FT. Parental Attitude to Children with Sickle Cell Disease in Selected Health Facilities in Irepodun Local Government, Kwara State, Nigeria Studies on Ethno-Medicine. 2011; (1): 33-40.
[20]	Fernandes AP, Pinheiro C, Januário JN, Cangussu CB, Macedo DL, Viana MB. Mortality of children with sickle cell disease: a population study. Jornal de Pediatria. 2010. 86(4): 279-284.
[21]	Abioye-Kuteyi EA, Oyegbade O, Bello I, Osakwe C. Sickle cell knowledge, premarital screening and marital decisions among local government workers in Ile-Ife, Nigeria. African J of Primary Health Care and Family Med. 2009; 1(1): Article 22. African Online Scientific Information Systems/AOSIS (Pty) Ltd
[22]	Moronkola OA, Fadairo RA. University students in Nigeria: knowledge, attitude toward sickle cell disease, and genetic counseling before marriage. National Library of Medicine. Internatl Quarterly J of Comm. Health Edu. 2007; 26(1): 85-93.

Cite This Article

Plain Text BibTeX RIS

APA Style

Tajudeen Olusegun Rasheed, Wasiu Adebowale Afolabi, Rukayat Ololade Abdul Rasheed, Rasheedat Adenike Ajala. (2018). Premarital Sickle Cell Genetic Screening Knowledge, Attitude and Practice Compared Among Married and Unmarried Youths in Nigeria. World Journal of Public Health, 3(3), 76-82. https://doi.org/10.11648/j.wjph.20180303.12

Copy | Download

ACS Style

Tajudeen Olusegun Rasheed; Wasiu Adebowale Afolabi; Rukayat Ololade Abdul Rasheed; Rasheedat Adenike Ajala. Premarital Sickle Cell Genetic Screening Knowledge, Attitude and Practice Compared Among Married and Unmarried Youths in Nigeria. World J. Public Health 2018, 3(3), 76-82. doi: 10.11648/j.wjph.20180303.12

Copy | Download

AMA Style

Tajudeen Olusegun Rasheed, Wasiu Adebowale Afolabi, Rukayat Ololade Abdul Rasheed, Rasheedat Adenike Ajala. Premarital Sickle Cell Genetic Screening Knowledge, Attitude and Practice Compared Among Married and Unmarried Youths in Nigeria. World J Public Health. 2018;3(3):76-82. doi: 10.11648/j.wjph.20180303.12

Copy | Download

@article{10.11648/j.wjph.20180303.12,
  author = {Tajudeen Olusegun Rasheed and Wasiu Adebowale Afolabi and Rukayat Ololade Abdul Rasheed and Rasheedat Adenike Ajala},
  title = {Premarital Sickle Cell Genetic Screening Knowledge, Attitude and Practice Compared Among Married and Unmarried Youths in Nigeria},
  journal = {World Journal of Public Health},
  volume = {3},
  number = {3},
  pages = {76-82},
  doi = {10.11648/j.wjph.20180303.12},
  url = {https://doi.org/10.11648/j.wjph.20180303.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.wjph.20180303.12},
  abstract = {Premarital sickle cell genetic screening is a test that determines the genotype of the intending couple before marriage. As a result, counseling is given before and after the test. This study assessed and compared the level of knowledge, attitude and practices of premarital sickle cell screening among married and unmarried youths in Epe, Nigeria. A cross-sectional descriptive research design was used to examine 370 participants, using stratified sampling technique. Data were collected with an instrument and analyzed, stating the mean, frequency and standard deviation. Scores were built for knowledge, attitude and practice. Chi-square test with p X2 = 6.359, Cramer’s v=0.09, p=0.0116, df = 1) and married (X2 = 12.9325, Cramer’s v=0.10, p=0.0003, df =1) youths. Similarly, an association exists between attitude and practices of premarital sickle cell genetic screening for unmarried youth (X2 = 20.3077, p=0.0007, Cramer’s v=0.17, df = 1) but for married youths there was no association (X2 = 0.0168, p = 0.8969, Cramer’s v=0.08, df = 1). Furthermore, finding revealed that 77% of the married participants did not have sickle cell genetic screening test before marriage, while 67% of the unmarried participants were not willing to carry out the test, due to fear of the unknown and stigma. Conclusively, the level of knowledge of the participants’ was good (70.06%), attitude was negative towards practices of premarital sickle cell genetic screening. Therefore, continuous health education that focuses on sickle cell genetic screening test could improve the practices among the youth to avert the associated morbidity and mortality.},
 year = {2018}
}

Copy | Download

TY  - JOUR
T1  - Premarital Sickle Cell Genetic Screening Knowledge, Attitude and Practice Compared Among Married and Unmarried Youths in Nigeria
AU  - Tajudeen Olusegun Rasheed
AU  - Wasiu Adebowale Afolabi
AU  - Rukayat Ololade Abdul Rasheed
AU  - Rasheedat Adenike Ajala
Y1  - 2018/08/09
PY  - 2018
N1  - https://doi.org/10.11648/j.wjph.20180303.12
DO  - 10.11648/j.wjph.20180303.12
T2  - World Journal of Public Health
JF  - World Journal of Public Health
JO  - World Journal of Public Health
SP  - 76
EP  - 82
PB  - Science Publishing Group
SN  - 2637-6059
UR  - https://doi.org/10.11648/j.wjph.20180303.12
AB  - Premarital sickle cell genetic screening is a test that determines the genotype of the intending couple before marriage. As a result, counseling is given before and after the test. This study assessed and compared the level of knowledge, attitude and practices of premarital sickle cell screening among married and unmarried youths in Epe, Nigeria. A cross-sectional descriptive research design was used to examine 370 participants, using stratified sampling technique. Data were collected with an instrument and analyzed, stating the mean, frequency and standard deviation. Scores were built for knowledge, attitude and practice. Chi-square test with p X2 = 6.359, Cramer’s v=0.09, p=0.0116, df = 1) and married (X2 = 12.9325, Cramer’s v=0.10, p=0.0003, df =1) youths. Similarly, an association exists between attitude and practices of premarital sickle cell genetic screening for unmarried youth (X2 = 20.3077, p=0.0007, Cramer’s v=0.17, df = 1) but for married youths there was no association (X2 = 0.0168, p = 0.8969, Cramer’s v=0.08, df = 1). Furthermore, finding revealed that 77% of the married participants did not have sickle cell genetic screening test before marriage, while 67% of the unmarried participants were not willing to carry out the test, due to fear of the unknown and stigma. Conclusively, the level of knowledge of the participants’ was good (70.06%), attitude was negative towards practices of premarital sickle cell genetic screening. Therefore, continuous health education that focuses on sickle cell genetic screening test could improve the practices among the youth to avert the associated morbidity and mortality.
VL  - 3
IS  - 3
ER  -

Copy | Download

Author Information

Tajudeen Olusegun Rasheed

Medical Department, Economic and Financial Crimes Commission, Ikoyi, Nigeria
Wasiu Adebowale Afolabi

School of Post Basic Psychiatric/Mental Health Nursing, Federal Neuropsychiatric Hospital, Yaba, Nigeria
Rukayat Ololade Abdul Rasheed

Tarukah Resources Consult, Agege, Nigeria
Rasheedat Adenike Ajala

Department of Nursing, National Open University, Victoria Island, Nigeria

Download PDF

Sections

Plain Text BibTeX RIS

APA Style

Tajudeen Olusegun Rasheed, Wasiu Adebowale Afolabi, Rukayat Ololade Abdul Rasheed, Rasheedat Adenike Ajala. (2018). Premarital Sickle Cell Genetic Screening Knowledge, Attitude and Practice Compared Among Married and Unmarried Youths in Nigeria. World Journal of Public Health, 3(3), 76-82. https://doi.org/10.11648/j.wjph.20180303.12

Copy | Download

ACS Style

Tajudeen Olusegun Rasheed; Wasiu Adebowale Afolabi; Rukayat Ololade Abdul Rasheed; Rasheedat Adenike Ajala. Premarital Sickle Cell Genetic Screening Knowledge, Attitude and Practice Compared Among Married and Unmarried Youths in Nigeria. World J. Public Health 2018, 3(3), 76-82. doi: 10.11648/j.wjph.20180303.12

Copy | Download

AMA Style

Tajudeen Olusegun Rasheed, Wasiu Adebowale Afolabi, Rukayat Ololade Abdul Rasheed, Rasheedat Adenike Ajala. Premarital Sickle Cell Genetic Screening Knowledge, Attitude and Practice Compared Among Married and Unmarried Youths in Nigeria. World J Public Health. 2018;3(3):76-82. doi: 10.11648/j.wjph.20180303.12

Copy | Download

@article{10.11648/j.wjph.20180303.12,
  author = {Tajudeen Olusegun Rasheed and Wasiu Adebowale Afolabi and Rukayat Ololade Abdul Rasheed and Rasheedat Adenike Ajala},
  title = {Premarital Sickle Cell Genetic Screening Knowledge, Attitude and Practice Compared Among Married and Unmarried Youths in Nigeria},
  journal = {World Journal of Public Health},
  volume = {3},
  number = {3},
  pages = {76-82},
  doi = {10.11648/j.wjph.20180303.12},
  url = {https://doi.org/10.11648/j.wjph.20180303.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.wjph.20180303.12},
  abstract = {Premarital sickle cell genetic screening is a test that determines the genotype of the intending couple before marriage. As a result, counseling is given before and after the test. This study assessed and compared the level of knowledge, attitude and practices of premarital sickle cell screening among married and unmarried youths in Epe, Nigeria. A cross-sectional descriptive research design was used to examine 370 participants, using stratified sampling technique. Data were collected with an instrument and analyzed, stating the mean, frequency and standard deviation. Scores were built for knowledge, attitude and practice. Chi-square test with p X2 = 6.359, Cramer’s v=0.09, p=0.0116, df = 1) and married (X2 = 12.9325, Cramer’s v=0.10, p=0.0003, df =1) youths. Similarly, an association exists between attitude and practices of premarital sickle cell genetic screening for unmarried youth (X2 = 20.3077, p=0.0007, Cramer’s v=0.17, df = 1) but for married youths there was no association (X2 = 0.0168, p = 0.8969, Cramer’s v=0.08, df = 1). Furthermore, finding revealed that 77% of the married participants did not have sickle cell genetic screening test before marriage, while 67% of the unmarried participants were not willing to carry out the test, due to fear of the unknown and stigma. Conclusively, the level of knowledge of the participants’ was good (70.06%), attitude was negative towards practices of premarital sickle cell genetic screening. Therefore, continuous health education that focuses on sickle cell genetic screening test could improve the practices among the youth to avert the associated morbidity and mortality.},
 year = {2018}
}

Copy | Download

TY  - JOUR
T1  - Premarital Sickle Cell Genetic Screening Knowledge, Attitude and Practice Compared Among Married and Unmarried Youths in Nigeria
AU  - Tajudeen Olusegun Rasheed
AU  - Wasiu Adebowale Afolabi
AU  - Rukayat Ololade Abdul Rasheed
AU  - Rasheedat Adenike Ajala
Y1  - 2018/08/09
PY  - 2018
N1  - https://doi.org/10.11648/j.wjph.20180303.12
DO  - 10.11648/j.wjph.20180303.12
T2  - World Journal of Public Health
JF  - World Journal of Public Health
JO  - World Journal of Public Health
SP  - 76
EP  - 82
PB  - Science Publishing Group
SN  - 2637-6059
UR  - https://doi.org/10.11648/j.wjph.20180303.12
AB  - Premarital sickle cell genetic screening is a test that determines the genotype of the intending couple before marriage. As a result, counseling is given before and after the test. This study assessed and compared the level of knowledge, attitude and practices of premarital sickle cell screening among married and unmarried youths in Epe, Nigeria. A cross-sectional descriptive research design was used to examine 370 participants, using stratified sampling technique. Data were collected with an instrument and analyzed, stating the mean, frequency and standard deviation. Scores were built for knowledge, attitude and practice. Chi-square test with p X2 = 6.359, Cramer’s v=0.09, p=0.0116, df = 1) and married (X2 = 12.9325, Cramer’s v=0.10, p=0.0003, df =1) youths. Similarly, an association exists between attitude and practices of premarital sickle cell genetic screening for unmarried youth (X2 = 20.3077, p=0.0007, Cramer’s v=0.17, df = 1) but for married youths there was no association (X2 = 0.0168, p = 0.8969, Cramer’s v=0.08, df = 1). Furthermore, finding revealed that 77% of the married participants did not have sickle cell genetic screening test before marriage, while 67% of the unmarried participants were not willing to carry out the test, due to fear of the unknown and stigma. Conclusively, the level of knowledge of the participants’ was good (70.06%), attitude was negative towards practices of premarital sickle cell genetic screening. Therefore, continuous health education that focuses on sickle cell genetic screening test could improve the practices among the youth to avert the associated morbidity and mortality.
VL  - 3
IS  - 3
ER  -

Copy | Download