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Mechanism of Platelets Stimulation by Non Thermal Plasma

Received: 2 October 2017    Accepted: 23 November 2017    Published: 1 February 2018
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Abstract

This study includes the constructing of plasma needle (plasma torch) at atmospheric pressure The torch is produced by applying high voltage 17kv and frequency 17 kHz. A total of seventy 70 Iraqi patients seeking for a medical consultation in Al-Ramadi Teaching Hospital includes in this study. The plasma treatment is applied in vitro experiments regarding clotting time, Prothrombin time. Patients are from both sexes and different age groups between (20-45 year) are included in this study. The results show that the decreasing of distances lead to increase in torch. Therefore, the plasma ions induce a number of clotting processes and thus accelerates blood clotting. It can be concluded that when the doses of exposure increases the clotting time decreases. Reducing the distance plays an important role in the generation of plasma, which leads to reduce blood clotting time, accelerates blood clotting, and stop bleeding. The Prothrombin time decreases after treatment with little, which have a significant role in the acceleration of blood clotting, as the mechanical Prothrombin turning fibrinogen into fibrin, which provides for the conglomerate platelets.

Published in International Journal of Chinese Medicine (Volume 2, Issue 1)
DOI 10.11648/j.ijcm.20180201.11
Page(s) 1-5
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Plasma Needle, Clotting Time, Prothrombin Time

References
[1] Mohammed U. Husain, "Low-Temperature Plasma Interactions in Medical Applications", Ph. D. Thesis, University of Baghdad, May, 2015.
[2] Ayan H., Fridman G., Gutsol A. F., Vasilets V. N., Fridman A. " Nanosecond-pulsed uniform dielectric-barrier discharge", IEEE Transactions on Plasma Science, 36, 504–508, 2008.
[3] Hoskinson A., Hershkowitz N. and Ashpis D., “Comparisons of force measurement methods for DBD plasma actuators in quiescent air,” AIAA, 485, 2009.
[4] Campbell, Neil A. (2008). Biology (8th ed.). London: Pearson Education. p. 912. ISBN 978-0-321-53616-7. "Platelets are pinched-off cytoplasmic fragments of specialized bone marrow cells. They are about 2–3µm in diameter and have no nuclei. Platelets serve both structural and molecular functions in blood clotting".
[5] McAleer JP, Sharma S, Kaplan EM, Persich G (2006). "Use of autologous platelet concentrate in a nonhealing lower extremity wound". Adv Skin Wound Care 19 (7): 354–63.
[6] Mohammed U. Hussein," Plasma Needles on the Teeth Structure and Compressibility". The Arab Journal of Sciences & Research Publishing, Vol. 2 - Issue (4): 2016, 5, 15 P. 46-50; Article no: AJSRP/M15216.
[7] Mahapatra B. & Mishra N., "Comparison of Bleeding Time and Clotting Time in Different Blood Groups", American Journal of Infectious Diseases 5, 2, 106-108, 2009.
[8] Ivy A. C., Nelson D., & Beecher G., J. Lab. Clinical Medicine, 26, 1812, 1949.
[9] McKenzie, Shirlyn B., "Clinical Laboratory Hematology", 785-786, 1954.
[10] Fritsma, George A. "Evaluation of Hemostasis." Hematology: Clinical Principles and Applications. Ed. Bernadette Rodak. W. B. Saunders Company: Philadelphia, 719-53, 2002.
[11] Horsti J, Uppa H, Vilpo JA, "Poor agreement among prothrombin time international normalized ratio methods: comparison of seven commercial reagents", Clin. Chem., 60-553, 3, 51, 2001.
[12] Fridman G., Shereshevsky A., Jost M. M., Brooks A. D." Bio-Medical Applications of Non-Thermal Atmospheric Pressure Plasma" in 37th AIAA Plasma dynamics and Lasers Conference. San Francisco, California., 2006.
[13] Kuchenbecker, M., Bibinov, N., kaemlimg, A., Wandke, D., Awakowicz, P. & Viol, W., "characterization of DBD plasma source for biomedical applications". J. Phys. D: Appl. phys., 42, 045212, 2009.
[14] Yildrim E. D., Ayan H., Vasilests V. N., Fridman G & Sum, W. "Effect of dielectric barrier discharge plasma on the attachment and proliferation of osteobalasts cultured over poly (E-caprolacton) scaffolds",. Plasma process. Polym., 5, 58-66, 2008.
[15] Deng X T, Shi J, Chen H L and Kong MG," Protein destruction by atmospheric pressure glow discharges", Appl. Phys. Lett., 90, 013903, 2007.
[16] Gregory Fridman, Alexey Shereshevsky, Marie Peddinghaus, Alexander Gutsol, Victor Vasilets, Ari Brooks, Manjula Balasubramanian, Gary Friedman, Alexander Fridman," Bio-Medical Applications of Non-Thermal Atmospheric Pressure Plasma" Plasma Medicine Lab, Drexel Plasma Institute, Drexel University, 3141 Chestnut, Philadelphia, PA 19104, 2006.
[17] O'Connell SM, Impeduglia T, Hessler K, Wang XJ, Carroll RJ, Dardik H. "Autologous platelet-rich fibrin matrix as cell therapy in the healing of chronic lower-extremity ulcers". Wound Repair Regen, 16, 6, 749–56, 2008.
[18] Knighton DR, Ciresi KF, Fiegel VD, Austin LL, Butler EL "Classification and treatment of chronic nonhealing wounds. Successful treatment with autologous platelet-derived wound healing factors (PDWHF)". Ann. Surg., 204, 3, 322–30, 1986.
[19] Balasubramanian, M.," Blood conservation and coagulation by non-thermal dielectric barrier discharge technology". Transfusion, 47, 2, 6, 2007.
[20] Fridman G., Peddinghaus M., Balasubramanian M., H. Ayan, Fridman A., Gustol A., and Brooks A. "Blood Coagulation and living tissue sterilization by floating –electrode dielectric barrier discharge in air", plasma chem. plasma process., 26, 425-442, 2006.
[21] Mohammed, U. Hussein, Rana T. Mohsen, 2016. "Water pollution removal by Non- thermal plasma jet". Mesopotamia Environmental Journal, Mesop. environ. j., Spicial Issue A.; 86-92 (proceding of 6th International conference for Environmental Science–University of Babylon).
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  • APA Style

    Mohammed Ubaid Hussein, Enas Soleman Yousif. (2018). Mechanism of Platelets Stimulation by Non Thermal Plasma. International Journal of Chinese Medicine, 2(1), 1-5. https://doi.org/10.11648/j.ijcm.20180201.11

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    ACS Style

    Mohammed Ubaid Hussein; Enas Soleman Yousif. Mechanism of Platelets Stimulation by Non Thermal Plasma. Int. J. Chin. Med. 2018, 2(1), 1-5. doi: 10.11648/j.ijcm.20180201.11

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    AMA Style

    Mohammed Ubaid Hussein, Enas Soleman Yousif. Mechanism of Platelets Stimulation by Non Thermal Plasma. Int J Chin Med. 2018;2(1):1-5. doi: 10.11648/j.ijcm.20180201.11

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  • @article{10.11648/j.ijcm.20180201.11,
      author = {Mohammed Ubaid Hussein and Enas Soleman Yousif},
      title = {Mechanism of Platelets Stimulation by Non Thermal Plasma},
      journal = {International Journal of Chinese Medicine},
      volume = {2},
      number = {1},
      pages = {1-5},
      doi = {10.11648/j.ijcm.20180201.11},
      url = {https://doi.org/10.11648/j.ijcm.20180201.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcm.20180201.11},
      abstract = {This study includes the constructing of plasma needle (plasma torch) at atmospheric pressure The torch is produced by applying high voltage 17kv and frequency 17 kHz. A total of seventy 70 Iraqi patients seeking for a medical consultation in Al-Ramadi Teaching Hospital includes in this study. The plasma treatment is applied in vitro experiments regarding clotting time, Prothrombin time. Patients are from both sexes and different age groups between (20-45 year) are included in this study. The results show that the decreasing of distances lead to increase in torch. Therefore, the plasma ions induce a number of clotting processes and thus accelerates blood clotting. It can be concluded that when the doses of exposure increases the clotting time decreases. Reducing the distance plays an important role in the generation of plasma, which leads to reduce blood clotting time, accelerates blood clotting, and stop bleeding. The Prothrombin time decreases after treatment with little, which have a significant role in the acceleration of blood clotting, as the mechanical Prothrombin turning fibrinogen into fibrin, which provides for the conglomerate platelets.},
     year = {2018}
    }
    

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  • TY  - JOUR
    T1  - Mechanism of Platelets Stimulation by Non Thermal Plasma
    AU  - Mohammed Ubaid Hussein
    AU  - Enas Soleman Yousif
    Y1  - 2018/02/01
    PY  - 2018
    N1  - https://doi.org/10.11648/j.ijcm.20180201.11
    DO  - 10.11648/j.ijcm.20180201.11
    T2  - International Journal of Chinese Medicine
    JF  - International Journal of Chinese Medicine
    JO  - International Journal of Chinese Medicine
    SP  - 1
    EP  - 5
    PB  - Science Publishing Group
    SN  - 2578-9473
    UR  - https://doi.org/10.11648/j.ijcm.20180201.11
    AB  - This study includes the constructing of plasma needle (plasma torch) at atmospheric pressure The torch is produced by applying high voltage 17kv and frequency 17 kHz. A total of seventy 70 Iraqi patients seeking for a medical consultation in Al-Ramadi Teaching Hospital includes in this study. The plasma treatment is applied in vitro experiments regarding clotting time, Prothrombin time. Patients are from both sexes and different age groups between (20-45 year) are included in this study. The results show that the decreasing of distances lead to increase in torch. Therefore, the plasma ions induce a number of clotting processes and thus accelerates blood clotting. It can be concluded that when the doses of exposure increases the clotting time decreases. Reducing the distance plays an important role in the generation of plasma, which leads to reduce blood clotting time, accelerates blood clotting, and stop bleeding. The Prothrombin time decreases after treatment with little, which have a significant role in the acceleration of blood clotting, as the mechanical Prothrombin turning fibrinogen into fibrin, which provides for the conglomerate platelets.
    VL  - 2
    IS  - 1
    ER  - 

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Author Information
  • Department of Physiology and Medical Physics, College of Medicine, Anbar University, Anbar, Iraq

  • Department of Physiology and Medical Physics, College of Medicine, Anbar University, Anbar, Iraq

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