Clinical Neurology and Neuroscience

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Dopa-Responsive Dystonia with Diurnal Fluctuation: A Case Report of an 18 Year Old Nigerian

Received: Oct. 25, 2017    Accepted: Feb. 03, 2018    Published: Jul. 04, 2018
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Abstract

Dopa-responsive dystonia, also known as hereditary progressive dystonia with diurnal variation, is a genetic disease characterized by childhood or adolescent onset of dystonia and sometimes associated with parkinsonian features. This is a case report of an 18 year old Nigerian University undergraduate with features of difficulty in speaking, stiffness of the body, gait difficulties, coarse tremors and toe-walking. There was a very marked improvement of symptoms and signs within 24-48 hours of the commencement of SinemetTM (levodopa/ carbidopa) 125mg/12.5mg daily. The patient was discharged after 5 days with normal gait.

DOI 10.11648/j.cnn.20180202.11
Published in Clinical Neurology and Neuroscience ( Volume 2, Issue 2, June 2018 )
Page(s) 23-26
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Dopa, Dystonia, Diurnal Variations, Levodopa/Carbidopa

References
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Cite This Article
  • APA Style

    Olusegun Adesola Busari, Paul Olowoyo, Segun Oladele Adeniyi, Bidemi Olayemi Onipede, Olisa Joseph, et al. (2018). Dopa-Responsive Dystonia with Diurnal Fluctuation: A Case Report of an 18 Year Old Nigerian. Clinical Neurology and Neuroscience, 2(2), 23-26. https://doi.org/10.11648/j.cnn.20180202.11

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    ACS Style

    Olusegun Adesola Busari; Paul Olowoyo; Segun Oladele Adeniyi; Bidemi Olayemi Onipede; Olisa Joseph, et al. Dopa-Responsive Dystonia with Diurnal Fluctuation: A Case Report of an 18 Year Old Nigerian. Clin. Neurol. Neurosci. 2018, 2(2), 23-26. doi: 10.11648/j.cnn.20180202.11

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    AMA Style

    Olusegun Adesola Busari, Paul Olowoyo, Segun Oladele Adeniyi, Bidemi Olayemi Onipede, Olisa Joseph, et al. Dopa-Responsive Dystonia with Diurnal Fluctuation: A Case Report of an 18 Year Old Nigerian. Clin Neurol Neurosci. 2018;2(2):23-26. doi: 10.11648/j.cnn.20180202.11

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  • @article{10.11648/j.cnn.20180202.11,
      author = {Olusegun Adesola Busari and Paul Olowoyo and Segun Oladele Adeniyi and Bidemi Olayemi Onipede and Olisa Joseph and Solomon Ogunniran},
      title = {Dopa-Responsive Dystonia with Diurnal Fluctuation: A Case Report of an 18 Year Old Nigerian},
      journal = {Clinical Neurology and Neuroscience},
      volume = {2},
      number = {2},
      pages = {23-26},
      doi = {10.11648/j.cnn.20180202.11},
      url = {https://doi.org/10.11648/j.cnn.20180202.11},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.cnn.20180202.11},
      abstract = {Dopa-responsive dystonia, also known as hereditary progressive dystonia with diurnal variation, is a genetic disease characterized by childhood or adolescent onset of dystonia and sometimes associated with parkinsonian features. This is a case report of an 18 year old Nigerian University undergraduate with features of difficulty in speaking, stiffness of the body, gait difficulties, coarse tremors and toe-walking. There was a very marked improvement of symptoms and signs within 24-48 hours of the commencement of SinemetTM (levodopa/ carbidopa) 125mg/12.5mg daily. The patient was discharged after 5 days with normal gait.},
     year = {2018}
    }
    

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    AB  - Dopa-responsive dystonia, also known as hereditary progressive dystonia with diurnal variation, is a genetic disease characterized by childhood or adolescent onset of dystonia and sometimes associated with parkinsonian features. This is a case report of an 18 year old Nigerian University undergraduate with features of difficulty in speaking, stiffness of the body, gait difficulties, coarse tremors and toe-walking. There was a very marked improvement of symptoms and signs within 24-48 hours of the commencement of SinemetTM (levodopa/ carbidopa) 125mg/12.5mg daily. The patient was discharged after 5 days with normal gait.
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Author Information
  • Department of Medicine, College of Medicine and Health Sciences, Afe Babalola University, Ado-Ekiti, Nigeria

  • Department of Medicine, College of Medicine and Health Sciences, Afe Babalola University, Ado-Ekiti, Nigeria

  • Department of Medicine, Landmark University Medical Centre, Omu-Aran, Nigeria

  • Department of Medicine, Landmark University Medical Centre, Omu-Aran, Nigeria

  • Department of Medicine, Landmark University Medical Centre, Omu-Aran, Nigeria

  • Department of Medicine, Landmark University Medical Centre, Omu-Aran, Nigeria

  • Section