Bronchiolitis obliterans organizing pneumonia (BOOP) is a rare disorder affecting the small airways, alveoli and the walls of small bronchi. This form of lung injury involves inflammation and stiffening of lung areas with organized tissue. There are several known causes of BOOP, and several systemic disorders have BOOP as an associated primary pulmonary lesion. An outbreak of BOOP among young women has been publicly reported in Taiwan from late 1994 and onward. The source of the illness was traced to the consumption of Sauropus androgynus. Herein, we describe a case of a 28-year-old woman who developed a rapid pulmonary toxicity after drinking fresh S. androgynus purée daily for a period of two months, as an alleged regimen for weight reduction. Ga-67 citrate imaging portrayed the inflammatory status in her eyes, parotids and lungs. Pathological pattern of open-lung biopsy specimens was characteristic of BOOP. The toxicity is believed related to alkaloid papaverine contained in the plant. Bioactive principles of S. androgynus and pathogenetic mechanism underlying BOOP remain unidentified.
| Published in | American Journal of Internal Medicine (Volume 5, Issue 6) |
| DOI | 10.11648/j.ajim.20170506.13 |
| Page(s) | 125-128 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
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Copyright © The Author(s), 2024. Published by Science Publishing Group |
Bronchiolitis Obliterans Organizing Pneumonia, Papaverine, Sauropus androgynous, Weight Reduction
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APA Style
Rong-Hsin Yang, Shan-Fan Yao, Yum-Kung Chu. (2017). Bronchiolitis Obliterans Organizing Pneumonia Following Consumption of Sauropus androgynus. American Journal of Internal Medicine, 5(6), 125-128. https://doi.org/10.11648/j.ajim.20170506.13
ACS Style
Rong-Hsin Yang; Shan-Fan Yao; Yum-Kung Chu. Bronchiolitis Obliterans Organizing Pneumonia Following Consumption of Sauropus androgynus. Am. J. Intern. Med. 2017, 5(6), 125-128. doi: 10.11648/j.ajim.20170506.13
AMA Style
Rong-Hsin Yang, Shan-Fan Yao, Yum-Kung Chu. Bronchiolitis Obliterans Organizing Pneumonia Following Consumption of Sauropus androgynus. Am J Intern Med. 2017;5(6):125-128. doi: 10.11648/j.ajim.20170506.13
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Download@article{10.11648/j.ajim.20170506.13,
author = {Rong-Hsin Yang and Shan-Fan Yao and Yum-Kung Chu},
title = {Bronchiolitis Obliterans Organizing Pneumonia Following Consumption of Sauropus androgynus},
journal = {American Journal of Internal Medicine},
volume = {5},
number = {6},
pages = {125-128},
doi = {10.11648/j.ajim.20170506.13},
url = {https://doi.org/10.11648/j.ajim.20170506.13},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20170506.13},
abstract = {Bronchiolitis obliterans organizing pneumonia (BOOP) is a rare disorder affecting the small airways, alveoli and the walls of small bronchi. This form of lung injury involves inflammation and stiffening of lung areas with organized tissue. There are several known causes of BOOP, and several systemic disorders have BOOP as an associated primary pulmonary lesion. An outbreak of BOOP among young women has been publicly reported in Taiwan from late 1994 and onward. The source of the illness was traced to the consumption of Sauropus androgynus. Herein, we describe a case of a 28-year-old woman who developed a rapid pulmonary toxicity after drinking fresh S. androgynus purée daily for a period of two months, as an alleged regimen for weight reduction. Ga-67 citrate imaging portrayed the inflammatory status in her eyes, parotids and lungs. Pathological pattern of open-lung biopsy specimens was characteristic of BOOP. The toxicity is believed related to alkaloid papaverine contained in the plant. Bioactive principles of S. androgynus and pathogenetic mechanism underlying BOOP remain unidentified.},
year = {2017}
}
TY - JOUR T1 - Bronchiolitis Obliterans Organizing Pneumonia Following Consumption of Sauropus androgynus AU - Rong-Hsin Yang AU - Shan-Fan Yao AU - Yum-Kung Chu Y1 - 2017/11/28 PY - 2017 N1 - https://doi.org/10.11648/j.ajim.20170506.13 DO - 10.11648/j.ajim.20170506.13 T2 - American Journal of Internal Medicine JF - American Journal of Internal Medicine JO - American Journal of Internal Medicine SP - 125 EP - 128 PB - Science Publishing Group SN - 2330-4324 UR - https://doi.org/10.11648/j.ajim.20170506.13 AB - Bronchiolitis obliterans organizing pneumonia (BOOP) is a rare disorder affecting the small airways, alveoli and the walls of small bronchi. This form of lung injury involves inflammation and stiffening of lung areas with organized tissue. There are several known causes of BOOP, and several systemic disorders have BOOP as an associated primary pulmonary lesion. An outbreak of BOOP among young women has been publicly reported in Taiwan from late 1994 and onward. The source of the illness was traced to the consumption of Sauropus androgynus. Herein, we describe a case of a 28-year-old woman who developed a rapid pulmonary toxicity after drinking fresh S. androgynus purée daily for a period of two months, as an alleged regimen for weight reduction. Ga-67 citrate imaging portrayed the inflammatory status in her eyes, parotids and lungs. Pathological pattern of open-lung biopsy specimens was characteristic of BOOP. The toxicity is believed related to alkaloid papaverine contained in the plant. Bioactive principles of S. androgynus and pathogenetic mechanism underlying BOOP remain unidentified. VL - 5 IS - 6 ER -
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