In the recent years, mushrooms are distinguished as important natural resources of immunotherapy which can be used as immunomodulating and immunostimulating in the management of some immunodeficiency diseases such as cancer, tumour, HIV, tuberculosis etc. Mushroom of the genus Pleurotus are good sources of several bioactive compounds which are able to augment or complement a desired immune response. Such bioactive compounds are polysaccharopeptides, polysaccharide-proteins, functional proteins (ubiquinone-9, nebrodeolysin, ubiquitin-like peptide and glycoprotein), glucans, proteoglycans and many others. Most of these bioactive compounds follow the immunomodulatory pathway mechanism of polysaccharide (β-glucan) from mushrooms by stimulating activities for both innate and adaptive immune systems. They proliferate and activate innate immune system components such as natural killer (NK) cells, neutrophils, and macrophages, and stimulate cytokines expression and secretion. These cytokines in turn activate adaptive immunity through the promotion of B-cells for antibodies production and stimulation of T-cell differentiation to T helper (Th1 and Th2) cells, which mediate cell and humoral immunities, respectively. In this review, the immunotherapeutic potential of oyster mushroom in relation to bioactive compounds produced is shown and this suggests that the oyster mushrooms are one of the most important natural products and functional foods.
| Published in |
International Journal of Immunology (Volume 3, Issue 2-1)
This article belongs to the Special Issue Immunotherapy |
| DOI | 10.11648/j.iji.s.2015030201.12 |
| Page(s) | 8-20 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Oyster Mushroom, Immunotherapy, Beta Glucan, Lectin, Polysaccharide
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APA Style
Oloke J. K., Adebayo E. A. (2015). Effectiveness of Immunotherapies from Oyster Mushroom (Pleurotus species) in the Management of Immunocompromised Patients. International Journal of Immunology, 3(2-1), 8-20. https://doi.org/10.11648/j.iji.s.2015030201.12
ACS Style
Oloke J. K.; Adebayo E. A. Effectiveness of Immunotherapies from Oyster Mushroom (Pleurotus species) in the Management of Immunocompromised Patients. Int. J. Immunol. 2015, 3(2-1), 8-20. doi: 10.11648/j.iji.s.2015030201.12
AMA Style
Oloke J. K., Adebayo E. A. Effectiveness of Immunotherapies from Oyster Mushroom (Pleurotus species) in the Management of Immunocompromised Patients. Int J Immunol. 2015;3(2-1):8-20. doi: 10.11648/j.iji.s.2015030201.12
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Download@article{10.11648/j.iji.s.2015030201.12,
author = {Oloke J. K. and Adebayo E. A.},
title = {Effectiveness of Immunotherapies from Oyster Mushroom (Pleurotus species) in the Management of Immunocompromised Patients},
journal = {International Journal of Immunology},
volume = {3},
number = {2-1},
pages = {8-20},
doi = {10.11648/j.iji.s.2015030201.12},
url = {https://doi.org/10.11648/j.iji.s.2015030201.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.iji.s.2015030201.12},
abstract = {In the recent years, mushrooms are distinguished as important natural resources of immunotherapy which can be used as immunomodulating and immunostimulating in the management of some immunodeficiency diseases such as cancer, tumour, HIV, tuberculosis etc. Mushroom of the genus Pleurotus are good sources of several bioactive compounds which are able to augment or complement a desired immune response. Such bioactive compounds are polysaccharopeptides, polysaccharide-proteins, functional proteins (ubiquinone-9, nebrodeolysin, ubiquitin-like peptide and glycoprotein), glucans, proteoglycans and many others. Most of these bioactive compounds follow the immunomodulatory pathway mechanism of polysaccharide (β-glucan) from mushrooms by stimulating activities for both innate and adaptive immune systems. They proliferate and activate innate immune system components such as natural killer (NK) cells, neutrophils, and macrophages, and stimulate cytokines expression and secretion. These cytokines in turn activate adaptive immunity through the promotion of B-cells for antibodies production and stimulation of T-cell differentiation to T helper (Th1 and Th2) cells, which mediate cell and humoral immunities, respectively. In this review, the immunotherapeutic potential of oyster mushroom in relation to bioactive compounds produced is shown and this suggests that the oyster mushrooms are one of the most important natural products and functional foods.},
year = {2015}
}
TY - JOUR T1 - Effectiveness of Immunotherapies from Oyster Mushroom (Pleurotus species) in the Management of Immunocompromised Patients AU - Oloke J. K. AU - Adebayo E. A. Y1 - 2015/02/07 PY - 2015 N1 - https://doi.org/10.11648/j.iji.s.2015030201.12 DO - 10.11648/j.iji.s.2015030201.12 T2 - International Journal of Immunology JF - International Journal of Immunology JO - International Journal of Immunology SP - 8 EP - 20 PB - Science Publishing Group SN - 2329-1753 UR - https://doi.org/10.11648/j.iji.s.2015030201.12 AB - In the recent years, mushrooms are distinguished as important natural resources of immunotherapy which can be used as immunomodulating and immunostimulating in the management of some immunodeficiency diseases such as cancer, tumour, HIV, tuberculosis etc. Mushroom of the genus Pleurotus are good sources of several bioactive compounds which are able to augment or complement a desired immune response. Such bioactive compounds are polysaccharopeptides, polysaccharide-proteins, functional proteins (ubiquinone-9, nebrodeolysin, ubiquitin-like peptide and glycoprotein), glucans, proteoglycans and many others. Most of these bioactive compounds follow the immunomodulatory pathway mechanism of polysaccharide (β-glucan) from mushrooms by stimulating activities for both innate and adaptive immune systems. They proliferate and activate innate immune system components such as natural killer (NK) cells, neutrophils, and macrophages, and stimulate cytokines expression and secretion. These cytokines in turn activate adaptive immunity through the promotion of B-cells for antibodies production and stimulation of T-cell differentiation to T helper (Th1 and Th2) cells, which mediate cell and humoral immunities, respectively. In this review, the immunotherapeutic potential of oyster mushroom in relation to bioactive compounds produced is shown and this suggests that the oyster mushrooms are one of the most important natural products and functional foods. VL - 3 IS - 2-1 ER -
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