Journal of Cancer Treatment and Research

Volume 7, Issue 4, December 2019

  • Review on: Signal Transduction Pathways as Therapeutic Targets in Cancer Therapy

    Getu Melesie Taye

    Issue: Volume 7, Issue 4, December 2019
    Pages: 69-76
    Received: Jul. 23, 2019
    Accepted: Sep. 09, 2019
    Published: Dec. 26, 2019
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    Abstract: Cancer is the second leading cause of mortality and it is a worldwide public health issue and has severe social and economic consequences. Cancer arises through a multistep, mutagenic process whereby cancer cells acquire a common set of properties including unlimited proliferation potential, self-sufficiency in growth signals, and resistance to ant... Show More
  • Effect of Nursing Intervention on Mental Health and Clinical Effect of Patients with Gastrointestinal Cancer

    Lina Wu, Lilian Gao, Jinfen Han

    Issue: Volume 7, Issue 4, December 2019
    Pages: 77-80
    Received: Dec. 01, 2019
    Accepted: Dec. 16, 2019
    Published: Dec. 26, 2019
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    Abstract: Objectives: Following gastrointestinal cancer patients have attracted the attention of the mental health and quality of life in postoperation, we explore outcome associated with nursing intervention improve the mental health and quality of life associated with gastrointestinal cancer patient after chemotherapy by questionnaires. Methods: 78 patient... Show More
  • Impact of Germline BRCA Mutation Status on Survival in Women with Metastatic Triple Negative Breast Cancer

    Kelsey E. Larson, Yen Y. Wang, Karissa Finke, Rachel Yoder, Kelsey Schwensen, Anne P. O’Dea, Qamar Khan, Lauren Nye, Jaimie Heldstab, Andrew K. Godwin, Bruce F. Kimler, Priyanka Sharma

    Issue: Volume 7, Issue 4, December 2019
    Pages: 81-86
    Received: Oct. 23, 2019
    Accepted: Dec. 07, 2019
    Published: Dec. 31, 2019
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    Abstract: Purpose: To investigate the association between germline deleterious BRCA1 or BRCA2 mutations (gBRCA+) and overall survival (OS) for patients with metastatic triple negative breast cancer (mTNBC). Methods: An IRB approved prospective multisite registry enrolling stage I-IV TNBC patients from 2011-2018 was utilized. Demographics, treatments, genetic... Show More