American Journal of Pediatrics

Volume 6, Issue 1, March 2020

  • Study of Prognostic Factors of Death in Children with Sickle Cell Diseases Followed at the Albert Royer National Children's Hospital Center, Dakar, Senegal

    Boubacar Gueye, Cheikh Tacko Diop, Ndéye Marième Diagne, Aminata Paye, Ibrahima Diagne

    Issue: Volume 6, Issue 1, March 2020
    Pages: 1-11
    Received: 9 December 2019
    Accepted: 2 January 2020
    Published: 21 January 2020
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    Abstract: Objectives. The objectives of our study are: i) estimate the survival time of cases of sickle cell diseases monitored at the Albert Royer National Children's Hospital Center, Dakar, Senegal from 1990 to 2010, ii) identify prognostic factors related to deaths. Methods. Comprehensive and retrospective survival analysis of the prognostic factors of de... Show More
  • Study of the Efficacy of Stimulation Physiotherapy in the Management of Severe Acute Malnutrition in Children Aged 6-59 Months in Bamako, Mali

    Maty Diagne Camara, Cheikh Tacko Diop, Oumar Bassoum, Jean Augustin Diégane Tine, Mohamed Ibrahim Mahmoud, Mamadou Makhtar Mbacké Leye, Mayacine Ndiongue, Kadim Niang, Adama Faye

    Issue: Volume 6, Issue 1, March 2020
    Pages: 12-21
    Received: 7 January 2020
    Accepted: 21 January 2020
    Published: 31 January 2020
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    Abstract: The main objective of this study is to analyse the effects of stimulation kinesitherapy on psychomotor and cognitive development in these children followed by Severe Acute Malnutrition, aged 6 months to 59 months in the intensive nutritional educational recovery units. Prospective cohort study with 2 groups: one group subjected to stimulation Kines... Show More
  • Prevalence of Electrocardiogram Abnormalities in Human Immunodeficiency Virus-Infected Children

    Ni Luh Sri Apsari, Eka Gunawijaya, Ni Putu Veny Kartika Yantie, Ketut Dewi Kumara Wati, Komang Ayu Witarini, Hendra Santoso

    Issue: Volume 6, Issue 1, March 2020
    Pages: 22-26
    Received: 17 December 2019
    Accepted: 10 January 2020
    Published: 7 February 2020
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    Abstract: HIV is an important cause of childhood morbidity and mortality affecting more than 1.3 million children worldwide, one of the morbidity is cardiac abnormalities. Cardiovascular abnormalities are still subclinical during childhood then become symtomatic in adulthood. Electrocardiography is effective to detect cardiac diseases. This study aimed to as... Show More
  • Correlation Between Interleukin-6 Serum and Hepcidin Serum in Obese Children

    Ni Komang Diah Saputri, I Gusti Lanang Sidiartha, I Made Gede Dwi Lingga Utama

    Issue: Volume 6, Issue 1, March 2020
    Pages: 27-30
    Received: 17 January 2020
    Accepted: 6 February 2020
    Published: 18 February 2020
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    Abstract: The number of obesity in children and adolescents is increasing. Obese children are believed to experience chronic inflammation as evidenced by high levels of inflammatory markers, especially interleukin-6 (IL-6). Obese children have high incidence of anemia caused by inflammatory process proven by high level of serum hepcidin. This study aimed to ... Show More
  • Lupus Nephritis in Children: 21-Year Experience of a Single Center in Belarus

    Ina Kazyra, Alexander Sukalo

    Issue: Volume 6, Issue 1, March 2020
    Pages: 31-36
    Received: 15 January 2020
    Accepted: 10 February 2020
    Published: 18 February 2020
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    Abstract: The article presents a historical and prospective analysis of the clinical and paraclinical data of a cohort of children suffering from systemic lupus erythematosus (SLE) with kidney damage, observed in a single center for 21 year. The case histories of 62 patients (51 girls and 11 boys) with a diagnosis of SLE and lupus nephritis (LN) who were mon... Show More
  • New Biomarkers in the Diagnosis of Kidney Injury in Children with Hereditary Nephritis and Tubulopaties

    Hanna Bialkevich, Ina Kazyra, Alexander Sukalo

    Issue: Volume 6, Issue 1, March 2020
    Pages: 37-41
    Received: 15 January 2020
    Accepted: 7 February 2020
    Published: 18 February 2020
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    Abstract: The search of non-invasive methods of diagnosis of kidney disease, new biomarkers of injury and its level is very important at present time. Such markers are KIM-1 (kidney injury molecule - 1), TGF-β1 (transforming growth factor - β1), RBP (retinol-binding protein) and β2-MG (β2 – microglobulin). β2-MG and RBP are low molecular weight proteins whic... Show More
  • The Sensitivity and Specificity of Kuesioner Praskrining Perkembangan to Detect Delayed Development in Children

    I. Gusti Ayu Trisna Windiani, I Gusti Agung Ngurah Sugitha Adnyana, Soetjiningsih

    Issue: Volume 6, Issue 1, March 2020
    Pages: 42-45
    Received: 2 February 2020
    Accepted: 14 February 2020
    Published: 21 February 2020
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    Abstract: Kuesioner Praskrining Perkembangan (KPSP) is Indonesian child development pre-screening questionnaire. One method that is very easy and quick to detect early developmental deviations is the pre-screening method. A pre-screening device must has validity, reliability, sensitivity, specificity, acceptability and suitability to local conditions. The ac... Show More
  • The Relation Between Maternal / Neonatal Vitamin D Levels and Early Onset Neonatal Sepsis

    Dina Kamal Ali, Iman Abdel Mohsen Shaheen

    Issue: Volume 6, Issue 1, March 2020
    Pages: 46-51
    Received: 12 January 2020
    Accepted: 17 February 2020
    Published: 26 February 2020
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    Abstract: In addition to its classical role in bone metabolism, vitamin D also has an immunomodulatory effects on immune function. Our aim was to determine the relation between serum 25-hydroxy vitamin D(25(OH)D) concentrations in newborns and their mothers with early onset neonatal sepsis (EOS). Also we aim to study the effect of severity of vitamin D defic... Show More
  • Perinatal Outcome in Hypertensive Disorder of Pregnancy - A Retrospective Study from a Tertiary Care Teaching Hospital

    Mustafa Captain, Sanjay Natu, Sameer Mhatre, Anjali Parekh, Manas Kumar Behera

    Issue: Volume 6, Issue 1, March 2020
    Pages: 52-57
    Received: 22 January 2020
    Accepted: 18 February 2020
    Published: 26 February 2020
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    Abstract: Hypertensive disorder of pregnancy (HDP) is a multisystem disorder of pregnancy known to jeopardize safe pregnancy thereby increasing the maternal and neonatal morbidity and mortality. A retrospective observational study of nine months duration was conducted to determine the fetal and early neonatal outcome in pregnancies complicated with HDP in a ... Show More
  • Antibiotic Prescription Pattern for Neonatal Sepsis at the University College Hospital, Ibadan; How Judicious

    Olukemi Oluwatoyin Tongo, Adeyemi Adeyinka Labaeka

    Issue: Volume 6, Issue 1, March 2020
    Pages: 58-61
    Received: 3 February 2020
    Accepted: 14 February 2020
    Published: 26 February 2020
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    Abstract: Multidrug-resistant bacterial infection is a global phenomenon and newborn units are not spared. Judicious use of antibiotics is one of the measures employed to curb the emergence of multidrug-resistant bacteria. It entails the use of empiric antibiotics based on knowledge of prevailing pathogens and antibiotic susceptibility patterns while awaitin... Show More
  • Neurotoxicity of Drugs in Children During Antenatal and Postnatal Development Periods

    Sergey Postnikov, Natalia Teplova, Aleksey Ermilin, Marya Kostyleva, Anna Gratzhianskaya, Galina Chervyakova, Yulia Eremina

    Issue: Volume 6, Issue 1, March 2020
    Pages: 62-67
    Received: 8 November 2019
    Accepted: 14 February 2020
    Published: 28 February 2020
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    Abstract: Neurotoxicity is not rare and periodically severe and even life-threatening adverse effect (AE) of drugs belonging to many therapeutic groups. Manifestations of neurotoxicity are variable: disturbances of peripheral nervous system (ototoxicity and ophtalmotoxicity, visceral neuropathy, neuromuscular blockade), involving of central nervous system (C... Show More
  • Experience of Treating Acute Appendicitis in Tashkent

    Akilov Khabibullo Ataullayevich, Urmanov Nozim Tursinaliyevich, Primov Farhod Sharifjonovich, Djurayev Jurat Atkhamovich, Yuldashev Tolib Akromovich, Khidoyatov Komronbek Zaynitdinovich

    Issue: Volume 6, Issue 1, March 2020
    Pages: 68-72
    Received: 20 January 2020
    Accepted: 17 February 2020
    Published: 28 February 2020
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    Abstract: Modern diagnostics of acute appendicitis in children should include abdominal ultrasound investigation upon admission to a specialized hospital, if necessary, in an ultrasound monitoring mode during clinical dynamic observation of the child. Surgical treatment is indicated only for destructive appendicitis. The method of a surgical treatment choice... Show More
  • Haptoglobin Polymorphism and Morbidity in Children Born Prematurely

    Irena Kessel, Michal Molad, Rada Nemirovsky, Keren Lavie-Nevo, Andrew Peter Levy, Shany Blum, Avi Rotschild

    Issue: Volume 6, Issue 1, March 2020
    Pages: 73-77
    Received: 26 January 2020
    Accepted: 24 February 2020
    Published: 28 February 2020
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    Abstract: Haptoglobin (Hp) is an acute phase protein. There exists three different Hp phenotypes that differ in their pro-inflammatory and anti-inflammatory action. Inflammation and oxidative stress are critically involved in many pathophysiological processes in childhood. We previously reported on the relationship of in-hospital clinical events and the Hp p... Show More