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Impact of Socioeconomic Status on In-Hospital Outcome of Patients with Acute Coronary Syndrome in Egypt
Ahmed Hosny El-Adawy,
Ghada Elkhawaga,
Samir Abd Elraheem,
Essam Mahfouz
Issue:
Volume 6, Issue 6, November 2017
Pages:
164-172
Received:
15 September 2017
Accepted:
11 October 2017
Published:
20 November 2017
Abstract: Cardiovascular problems are still the leading cause of deaths globally. Socioeconomic inequality continues to pose a challenge to health care suppliers and can greatly affect the clinical outcome of medical problems, especially in the cardiovascular field. This study aimed to assess the in-hospital outcome of patients with acute coronary syndrome admitted in the coronary care unit and to determine the relation between socioeconomic status (SES) and in-hospital outcome of acute coronary syndrome. A prospective observational study was conducted on 301 patients presented with acute coronary syndrome during the period from August 2015 to May 2016. A questionnaire was used to assess their socioeconomic status. Admitted patients with acute coronary syndrome (ACS) were classified into 31 (10.3%) patients with non-ST segment elevation myocardial infarction (NSTEMI), 162 (53.8%) with ST segment elevation myocardial infarction STEMI and 108 (35.9%) with unstable angina (UA). According to patients SES, they were classified as 77 with high SES, 74 with middle SES, 84 with low SES, and 66 with very low SES. The study revealed that the lower socioeconomic status was statistically significant associated with increase of acute coronary syndrome mortality (P <0.001), the incidence of impaired left ventricular function, heart failure and stroke was associated. While, lower socioeconomic status was significantly associated decrease in the incidence of coronary angiography and percutaneous intervention. No significant change in the incidence of arrhythmia and major bleeding between socioeconomic status classes. Lower socioeconomic status in patients with acute coronary syndrome was considered as a risk factor for increased in-hospital mortality, stroke, impaired left ventricular function, and heart failure. To the best of author’s knowledge, this study considered first report in Egypt discussing the in-hospital outcome of patients with ACS and to determine the relation between SES and in-hospital outcome of ACS patients.
Abstract: Cardiovascular problems are still the leading cause of deaths globally. Socioeconomic inequality continues to pose a challenge to health care suppliers and can greatly affect the clinical outcome of medical problems, especially in the cardiovascular field. This study aimed to assess the in-hospital outcome of patients with acute coronary syndrome a...
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Continuous Glucose Monitoring in the Cardiac ICU: Current Use and Future Directions
Laura A. Scrimgeour,
Brittany A. Potz,
Frank W. Sellke,
M. Ruhul Abid
Issue:
Volume 6, Issue 6, November 2017
Pages:
173-176
Received:
4 September 2017
Accepted:
24 October 2017
Published:
24 November 2017
Abstract: Perioperative glucose control is highly important, particularly for patients undergoing cardiac surgery. Variable glucose levels before, during and after cardiac surgery lead to increased post-operative complications and patient mortality. [1] Current methods for intensive monitoring and treating hyperglycemia in the Intensive Care Unit (ICU) usually involve hourly glucose monitoring and continuous intravenous insulin infusions. With the advent of more accurate subcutaneous glucose monitoring systems, the role of improved glucose control with newer systems deserves consideration for widespread adoption.
Abstract: Perioperative glucose control is highly important, particularly for patients undergoing cardiac surgery. Variable glucose levels before, during and after cardiac surgery lead to increased post-operative complications and patient mortality. [1] Current methods for intensive monitoring and treating hyperglycemia in the Intensive Care Unit (ICU) usual...
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Selected Pharmacological Applications of 1st Row Transition Metal Complexes: A review
Md. Saddam Hossain,
Pijush Kanti Roy,
Roushown Ali,
C. M. Zakaria,
Md. Kudrat-E-Zahan
Issue:
Volume 6, Issue 6, November 2017
Pages:
177-191
Received:
1 August 2017
Accepted:
7 August 2017
Published:
27 November 2017
Abstract: Ninety elements occur naturally on earth. Out of these, nine are radioactive and among the remaining eighty one that could support life, sixty one are metals. Our bodies have approximately 3% metal. Researchers have been established that some of metal complexes were biologically active. A significantly rising interest in the design of metal complexes as drugs and diagnostic agents is currently observed in the area of scientific inquiry, specifically termed medicinal inorganic chemistry. Investigations in this area focus mostly on the speciation of metal species in biological media based on possible interactions of these metal ions with diverse biomolecules. In an effort to contribute to future development of new therapeutics or diagnostic agents metallo pharmaceuticals used as anticancer agents, anti-HIV, metal-mediated antibiotics, antibacterials, antivirals, antiparasitics, antiarthritics, antidiabetics and radio-sensitizing agents appear in therapeutic medicinal inorganic chemistry. The medicinal uses and applications of metals and metal complexes are of increasing clinical and commercial importance.
Abstract: Ninety elements occur naturally on earth. Out of these, nine are radioactive and among the remaining eighty one that could support life, sixty one are metals. Our bodies have approximately 3% metal. Researchers have been established that some of metal complexes were biologically active. A significantly rising interest in the design of metal complex...
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Intelligent Classification Models for Gestational Diabetes: Comparative Study
Eboka Andrew Okonji,
Okobah Ifeoma Patricia,
Oluwatoyin Yerokun Mary
Issue:
Volume 6, Issue 6, November 2017
Pages:
192-200
Received:
5 April 2017
Accepted:
8 October 2017
Published:
7 December 2017
Abstract: Diabetes mellitus, a metabolic disease that features high glucose levels in the body with the inability of the body to secret enough insulin to breakdown glucose, or such a body is resistant to the effects of insulin. Nigeria and other nations of the world have become aware of the inherent threats to life of gestational diabetes in mothers with or without previous cases and its tendencies to metamorphose into Type-II. Our study presents a comparative study of classification models using both the supervised (K-nearest neighborhood and Quadratic Discriminant Analysis) and unsupervised (Profile Hidden Markov Model and Memetic algorithm) methods – which aims at early detection as well as improve early diagnosis via data-mining tools. Adopted dataset is split into: training (in some cases, retraining) and testing to aid model validation. Results show that age, obesity and family ties to the second degree, environmental conditions of inhabitance are critical factors that can increase likelihood. Gestational diabetes in mothers with or without previous cases were confirmed if: (a) history of babies weighing > 4.5kg at birth, (b) insulin resistance with polycystic ovary syndrome, and (c) abnormal tolerance to insulin. Also, PHMM outperforms Memetic algorithm in some cases; while memetic algorithm outperforms PHMM in some cases.
Abstract: Diabetes mellitus, a metabolic disease that features high glucose levels in the body with the inability of the body to secret enough insulin to breakdown glucose, or such a body is resistant to the effects of insulin. Nigeria and other nations of the world have become aware of the inherent threats to life of gestational diabetes in mothers with or ...
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Survival Analysis of Patients with End Stage Renal Disease the Case of Adama Hospital, Ethiopia
Mekiya Hussein,
Geremew Muleta,
Dinberu Seyoum,
Demeke Kifle,
Dechasa Bedada
Issue:
Volume 6, Issue 6, November 2017
Pages:
201-208
Received:
18 October 2017
Accepted:
16 November 2017
Published:
15 December 2017
Abstract: Background: Chronic kidney disease (CKD) with diagonesised end-stage renal disease (ESRD) is common public health problems worldwide. This study was aimed to investigate socio-economics and clinical characteristics determinants among end-stage renal disease (ESRD) population. Method: This study is a retrospective cohort design which was conducted during May 2012 to April 2016 and included 500 ESRD patients at Adama Hospital Medical College. Retrospectives data were gathered by reviewing patients’ medical and surgical wards history. The Cox PH regression and parametric survival (Weibull, Log-logistic and log normal) models were molded and compared for examining survival analysis of ESRD patient using R statistical package software. Results: The study participants are 500 ESRD patients, 72.40% were alive at the end of this study, while 27.40% were died. The survival time of ESRD Majority of patients (66.20%) were female. Log-normal model had fitted the ESRD data set best relatively among possible candidate models. The age at the time of admission to ESRD (HR=0.94, p-value < 0.05), female (HR=0.54, p-value <0.05) and family history (HR=0.45, p-value<0.05) had significantly shorter survival time of ESRD patients to mortality. Conclusion: parametric survival model with baseline hazard lognormal distribution was found appropriate to our dataset. This study identified that having ESRD with complications increases the probability of death. The family history of experiencing ESRD is a driver for being ESRD patient. Female patients had greater risk of death than males in this study. Age specific follow-up is necessary to reduce the mortality related to ESRD.
Abstract: Background: Chronic kidney disease (CKD) with diagonesised end-stage renal disease (ESRD) is common public health problems worldwide. This study was aimed to investigate socio-economics and clinical characteristics determinants among end-stage renal disease (ESRD) population. Method: This study is a retrospective cohort design which was conducted d...
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Phytochemical and Proximate Analysis of Some Medicinal Leaves
Abiodun Bukunmi Aborisade,
Adewale Adetutu,
Abiodun Olusoji Owoade
Issue:
Volume 6, Issue 6, November 2017
Pages:
209-214
Received:
1 June 2017
Accepted:
11 July 2017
Published:
25 December 2017
Abstract: The proximate analysis and the phytochemical constituents were investigated in Magnifera, Morinda lucida, Parquetina nigrescens, Oscmium gratissimum, Chenopodium ambrosioides and Veronia amygaldalina using standard reference methods. The proximate analysis in % showed that Chenopodium ambrosioides had the highest amount of ash content of 17.30 and moisture content of 89.40 while Magnifera indica had the lowest amount of ash content 12.04 and moisture content 68.40. Veronia amygaldalina had the highest amount of protein 30.02 and carbohydrate 54.00 while Parquetina nigrescens had the least amount of protein 25.06 and carbohydrate 40.23. Parquetina nigrescens had the highest amount of crude fibre of 25.05 while Chenopodium ambrosioides had the highest amount of crude fat 18.22. The moisture content was found to be 89.40%, ash content 17.30, fat 18.22%, protein 30.02%, crude fibre 25.05% and carbohydrate 54.00%. The phytochemical constituents indicated flavonoid 28.58% alkaloid 25.84% and tannin 2.94% in Magnifera indica, Veronia amygaldalina and Morinda lucida respectively. The presence of high secondary metabolites in the leaves are good indication that if the plant is subjected to further research such as identification and characterization of plant, bioactive compounds with strong biological activities may be isolated and novel compounds may also be identified.
Abstract: The proximate analysis and the phytochemical constituents were investigated in Magnifera, Morinda lucida, Parquetina nigrescens, Oscmium gratissimum, Chenopodium ambrosioides and Veronia amygaldalina using standard reference methods. The proximate analysis in % showed that Chenopodium ambrosioides had the highest amount of ash content of 17.30 and ...
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