Rare Primary Mandibular Chondrogenic Sarcoma in a Middle Aged Woman – Imaging Perspective

Osawe Abebe Austine; Ayinde Junaid Babatunde; Saleh Mohammed Kabir; Aliyu Abubakar Otaru

doi:doi:10.11648/j.wjmcr.20220301.11

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Rare Primary Mandibular Chondrogenic Sarcoma in a Middle Aged Woman – Imaging Perspective

Osawe Abebe Austine, Ayinde Junaid Babatunde, Saleh Mohammed Kabir, Aliyu Abubakar Otaru

Published in World Journal of Medical Case Reports (Volume 3, Issue 1)

Received: 14 December 2021 Accepted: 4 January 2022 Published: 12 January 2022

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Abstract

Chondrogenic sarcomas (CSs) are uncommon cartilaginous neoplasms with rare occurrence in the head and neck region where the maxilla is most commonly affected. Histologically, they are hypercellular lesions with abundant amount of hyaline type cartilage and they range from well-differentiated growth resembling benign cartilage tumour to high-grade malignancy with aggressive local behaviour and potential to metastasize. Only few cases of mandibular affectation have been reported with fewer cases involving the nasal cavity, larynx, skull and cervical vertebrae. Here a case of high grade, primary right hemimandibular CS in a 45 year old woman presenting with right jaw swelling and a discharging sinus following tooth extraction is reported. Initial x-ray examination of the skull demonstrated ‘sunray’ pattern in the mass which raised high index of suspicion for an aggressive process. Computed tomography (CT) imaging of the jaws showed the lesion to be destructive with adjacent soft tissue involvement. It also aided definition of tumour extent which was necessary for surgical planning. The mass was excised and histologic evaluation of the specimen revealed atypical chondrocytes with mitotic figures on chondromyxoid background consistent with high grade chondrosarcoma. The aim of this case presentation is to provide insight into the role played by three dimensional imaging modalities (CT and MRI) in diagnosis and management of malignant jaw lesions.

Published in	World Journal of Medical Case Reports (Volume 3, Issue 1)
DOI	10.11648/j.wjmcr.20220301.11
Page(s)	1-4
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2022. Published by Science Publishing Group

Keywords

Chondrosarcoma, Mandible, Imaging

References

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[2]	Prado FO, Nishimoto IN, Perez DE, Kowalski LP, Lopes MA. Head and neck chondrosarcoma: analysis of 16 cases. Br J Oral Maxillofac Surg. 2009; 47: 555-557.
[3]	Fayda M, Aksu G, Yaman Agaoglu F, Karadeniz A, Darendeliler E, Altun M, et al. The role of surgery and radiotherapy in treatment of soft tissue sarcomas of the head and neck region: review of 30 cases. J Craniomaxillofac Surg. 2009; 37: 42-48.
[4]	Limaiem F, Davis DD, Sticco KL, Chondrosarcoma. In: Statpearls [internet]. Treasure Island (FL): Statepearl Publishing; 2021.
[5]	Saito K, Unni KK, Wollan PC, Lund BA. Chondrosarcoma of the jaw and facial bones. Cancer 1995; 76: 1550 1558.
[6]	Angela C. Chi. Bone Pathology: In: Neville, Damm, Allen, Bouquot editors. Text Book of Oral and Maxillofacial Pathology. 3rd ed. Missouri: Elsevier; 2009. p. 664 9.
[7]	Greer RO, Rohrer MD, Young SK. Non-odontogenic tumors. In: Thewley SE, Panje WR (eds.) Comprehensive Management of Head and Neck Tumors. WB-Saunder's Company, Oxford 1987. pp. 1510-59.
[8]	Murphy MD, Walker EA, Wilson AJ et al. From the archive of the AFIP. Imaging of primary chondrosarcoma: Radiologic-Pathologic correlation. Radiographics 2003; 23: 1245.
[9]	Sammartino G, Marenzi G. Howard C, Minimo C et al. Managing Chondrosarcoma of the Jaw. J Oral Maxillofac Surg 2008; 66: 2349-2355.
[10]	Hackney FL, Aragon SB, Aufdemorte TB, Holt GR, Van Sickels JE. Chondrosarcoma of the jaws: Clinical findings, histopathology, and treatment. Oral Surg Oral Med Oral Pathol 1991; 71: 139-43.
[11]	Selz PA, Konrad HR, Woolbright E. Chondrosarcoma of the maxilla: A case report and review. Otolaryngol Head Neck Surg 1997; 116: 399-400.
[12]	Jindal G, Batra SS, Badwal JS, Uppal S, Bhandari S, Surgical management of chondrosarcoma of head and neck. Int Dent J Stud Res 2016; 4: 101-104.
[13]	Burkey BB, Hoffman HT, Baker SR, Thornton AF, McClatchey KD. Chondrosarcoma of the head and neck. Laryngoscope 1990; 100: 1301–1305.
[14]	Ruark DS, Schlehaider UK, Shah JP. Chondrosarcomas of the head and neck. World J Surg 1992; 16: 1010–1015.

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APA Style

Osawe Abebe Austine, Ayinde Junaid Babatunde, Saleh Mohammed Kabir, Aliyu Abubakar Otaru. (2022). Rare Primary Mandibular Chondrogenic Sarcoma in a Middle Aged Woman – Imaging Perspective. World Journal of Medical Case Reports, 3(1), 1-4. https://doi.org/10.11648/j.wjmcr.20220301.11

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ACS Style

Osawe Abebe Austine; Ayinde Junaid Babatunde; Saleh Mohammed Kabir; Aliyu Abubakar Otaru. Rare Primary Mandibular Chondrogenic Sarcoma in a Middle Aged Woman – Imaging Perspective. World J. Med. Case Rep. 2022, 3(1), 1-4. doi: 10.11648/j.wjmcr.20220301.11

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AMA Style

Osawe Abebe Austine, Ayinde Junaid Babatunde, Saleh Mohammed Kabir, Aliyu Abubakar Otaru. Rare Primary Mandibular Chondrogenic Sarcoma in a Middle Aged Woman – Imaging Perspective. World J Med Case Rep. 2022;3(1):1-4. doi: 10.11648/j.wjmcr.20220301.11

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@article{10.11648/j.wjmcr.20220301.11,
  author = {Osawe Abebe Austine and Ayinde Junaid Babatunde and Saleh Mohammed Kabir and Aliyu Abubakar Otaru},
  title = {Rare Primary Mandibular Chondrogenic Sarcoma in a Middle Aged Woman – Imaging Perspective},
  journal = {World Journal of Medical Case Reports},
  volume = {3},
  number = {1},
  pages = {1-4},
  doi = {10.11648/j.wjmcr.20220301.11},
  url = {https://doi.org/10.11648/j.wjmcr.20220301.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.wjmcr.20220301.11},
  abstract = {Chondrogenic sarcomas (CSs) are uncommon cartilaginous neoplasms with rare occurrence in the head and neck region where the maxilla is most commonly affected. Histologically, they are hypercellular lesions with abundant amount of hyaline type cartilage and they range from well-differentiated growth resembling benign cartilage tumour to high-grade malignancy with aggressive local behaviour and potential to metastasize. Only few cases of mandibular affectation have been reported with fewer cases involving the nasal cavity, larynx, skull and cervical vertebrae. Here a case of high grade, primary right hemimandibular CS in a 45 year old woman presenting with right jaw swelling and a discharging sinus following tooth extraction is reported. Initial x-ray examination of the skull demonstrated ‘sunray’ pattern in the mass which raised high index of suspicion for an aggressive process. Computed tomography (CT) imaging of the jaws showed the lesion to be destructive with adjacent soft tissue involvement. It also aided definition of tumour extent which was necessary for surgical planning. The mass was excised and histologic evaluation of the specimen revealed atypical chondrocytes with mitotic figures on chondromyxoid background consistent with high grade chondrosarcoma. The aim of this case presentation is to provide insight into the role played by three dimensional imaging modalities (CT and MRI) in diagnosis and management of malignant jaw lesions.},
 year = {2022}
}

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TY  - JOUR
T1  - Rare Primary Mandibular Chondrogenic Sarcoma in a Middle Aged Woman – Imaging Perspective
AU  - Osawe Abebe Austine
AU  - Ayinde Junaid Babatunde
AU  - Saleh Mohammed Kabir
AU  - Aliyu Abubakar Otaru
Y1  - 2022/01/12
PY  - 2022
N1  - https://doi.org/10.11648/j.wjmcr.20220301.11
DO  - 10.11648/j.wjmcr.20220301.11
T2  - World Journal of Medical Case Reports
JF  - World Journal of Medical Case Reports
JO  - World Journal of Medical Case Reports
SP  - 1
EP  - 4
PB  - Science Publishing Group
SN  - 2994-726X
UR  - https://doi.org/10.11648/j.wjmcr.20220301.11
AB  - Chondrogenic sarcomas (CSs) are uncommon cartilaginous neoplasms with rare occurrence in the head and neck region where the maxilla is most commonly affected. Histologically, they are hypercellular lesions with abundant amount of hyaline type cartilage and they range from well-differentiated growth resembling benign cartilage tumour to high-grade malignancy with aggressive local behaviour and potential to metastasize. Only few cases of mandibular affectation have been reported with fewer cases involving the nasal cavity, larynx, skull and cervical vertebrae. Here a case of high grade, primary right hemimandibular CS in a 45 year old woman presenting with right jaw swelling and a discharging sinus following tooth extraction is reported. Initial x-ray examination of the skull demonstrated ‘sunray’ pattern in the mass which raised high index of suspicion for an aggressive process. Computed tomography (CT) imaging of the jaws showed the lesion to be destructive with adjacent soft tissue involvement. It also aided definition of tumour extent which was necessary for surgical planning. The mass was excised and histologic evaluation of the specimen revealed atypical chondrocytes with mitotic figures on chondromyxoid background consistent with high grade chondrosarcoma. The aim of this case presentation is to provide insight into the role played by three dimensional imaging modalities (CT and MRI) in diagnosis and management of malignant jaw lesions.
VL  - 3
IS  - 1
ER  -

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Author Information

Osawe Abebe Austine

Department of Radiology, Nigeria Navy Reference Hospital Ojo, Lagos, Nigeria
Ayinde Junaid Babatunde

Department of Radiology, Nigeria Navy Reference Hospital Ojo, Lagos, Nigeria
Saleh Mohammed Kabir

Department of Radiology, Aminu Kano Teaching Hospital/Bayero University Kano, Kano, Nigeria
Aliyu Abubakar Otaru

Department of Oto-rhino-laryngology, Nigeria Navy Reference Hospital Ojo, Lagos, Nigeria

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APA Style

Osawe Abebe Austine, Ayinde Junaid Babatunde, Saleh Mohammed Kabir, Aliyu Abubakar Otaru. (2022). Rare Primary Mandibular Chondrogenic Sarcoma in a Middle Aged Woman – Imaging Perspective. World Journal of Medical Case Reports, 3(1), 1-4. https://doi.org/10.11648/j.wjmcr.20220301.11

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ACS Style

Osawe Abebe Austine; Ayinde Junaid Babatunde; Saleh Mohammed Kabir; Aliyu Abubakar Otaru. Rare Primary Mandibular Chondrogenic Sarcoma in a Middle Aged Woman – Imaging Perspective. World J. Med. Case Rep. 2022, 3(1), 1-4. doi: 10.11648/j.wjmcr.20220301.11

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AMA Style

Osawe Abebe Austine, Ayinde Junaid Babatunde, Saleh Mohammed Kabir, Aliyu Abubakar Otaru. Rare Primary Mandibular Chondrogenic Sarcoma in a Middle Aged Woman – Imaging Perspective. World J Med Case Rep. 2022;3(1):1-4. doi: 10.11648/j.wjmcr.20220301.11

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@article{10.11648/j.wjmcr.20220301.11,
  author = {Osawe Abebe Austine and Ayinde Junaid Babatunde and Saleh Mohammed Kabir and Aliyu Abubakar Otaru},
  title = {Rare Primary Mandibular Chondrogenic Sarcoma in a Middle Aged Woman – Imaging Perspective},
  journal = {World Journal of Medical Case Reports},
  volume = {3},
  number = {1},
  pages = {1-4},
  doi = {10.11648/j.wjmcr.20220301.11},
  url = {https://doi.org/10.11648/j.wjmcr.20220301.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.wjmcr.20220301.11},
  abstract = {Chondrogenic sarcomas (CSs) are uncommon cartilaginous neoplasms with rare occurrence in the head and neck region where the maxilla is most commonly affected. Histologically, they are hypercellular lesions with abundant amount of hyaline type cartilage and they range from well-differentiated growth resembling benign cartilage tumour to high-grade malignancy with aggressive local behaviour and potential to metastasize. Only few cases of mandibular affectation have been reported with fewer cases involving the nasal cavity, larynx, skull and cervical vertebrae. Here a case of high grade, primary right hemimandibular CS in a 45 year old woman presenting with right jaw swelling and a discharging sinus following tooth extraction is reported. Initial x-ray examination of the skull demonstrated ‘sunray’ pattern in the mass which raised high index of suspicion for an aggressive process. Computed tomography (CT) imaging of the jaws showed the lesion to be destructive with adjacent soft tissue involvement. It also aided definition of tumour extent which was necessary for surgical planning. The mass was excised and histologic evaluation of the specimen revealed atypical chondrocytes with mitotic figures on chondromyxoid background consistent with high grade chondrosarcoma. The aim of this case presentation is to provide insight into the role played by three dimensional imaging modalities (CT and MRI) in diagnosis and management of malignant jaw lesions.},
 year = {2022}
}

Copy | Download

TY  - JOUR
T1  - Rare Primary Mandibular Chondrogenic Sarcoma in a Middle Aged Woman – Imaging Perspective
AU  - Osawe Abebe Austine
AU  - Ayinde Junaid Babatunde
AU  - Saleh Mohammed Kabir
AU  - Aliyu Abubakar Otaru
Y1  - 2022/01/12
PY  - 2022
N1  - https://doi.org/10.11648/j.wjmcr.20220301.11
DO  - 10.11648/j.wjmcr.20220301.11
T2  - World Journal of Medical Case Reports
JF  - World Journal of Medical Case Reports
JO  - World Journal of Medical Case Reports
SP  - 1
EP  - 4
PB  - Science Publishing Group
SN  - 2994-726X
UR  - https://doi.org/10.11648/j.wjmcr.20220301.11
AB  - Chondrogenic sarcomas (CSs) are uncommon cartilaginous neoplasms with rare occurrence in the head and neck region where the maxilla is most commonly affected. Histologically, they are hypercellular lesions with abundant amount of hyaline type cartilage and they range from well-differentiated growth resembling benign cartilage tumour to high-grade malignancy with aggressive local behaviour and potential to metastasize. Only few cases of mandibular affectation have been reported with fewer cases involving the nasal cavity, larynx, skull and cervical vertebrae. Here a case of high grade, primary right hemimandibular CS in a 45 year old woman presenting with right jaw swelling and a discharging sinus following tooth extraction is reported. Initial x-ray examination of the skull demonstrated ‘sunray’ pattern in the mass which raised high index of suspicion for an aggressive process. Computed tomography (CT) imaging of the jaws showed the lesion to be destructive with adjacent soft tissue involvement. It also aided definition of tumour extent which was necessary for surgical planning. The mass was excised and histologic evaluation of the specimen revealed atypical chondrocytes with mitotic figures on chondromyxoid background consistent with high grade chondrosarcoma. The aim of this case presentation is to provide insight into the role played by three dimensional imaging modalities (CT and MRI) in diagnosis and management of malignant jaw lesions.
VL  - 3
IS  - 1
ER  -

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