The aim of this work is to assess the antimicrobial potential of cassia occidentalis flax (Caesalpiniaceae) leaf extracts on drug-resistant microbial strains, in order to bring phytotherapeutic prescriptions into line with the potential biological activities of the chemical constituents present. Aqueous and hydro-ethanolic extracts were prepared according to the methods of Zirihi and Kra (2003). The antimicrobial activities were determined by measuring the rate of inhibition of microbial growth, diffusion on a solid medium and dilution in a liquid medium. In addition, the mode of action of the active extracts was determined by the ratio of the minimum fungicidal concentration to the minimum inhibitory concentration (MFC/MIC). Aqueous and hydroalcoholic extracts from the leaves of C. occidentalis have been shown to have antimicrobial activity. These extracts inhibited the proliferation of C. albicans strains resistant to nystatin. The activity of the aqueous extracts was similar to that obtained with the hydroalcoholic extracts. However, both types of extract showed no significant efficacy against S. aureus, E. coli and K. pneumoniae strains at the doses used (200 mg/ml; 100 mg/ml and 50 mg/ml) in all the pharmacological tests repeated during this study.
| Published in | International Journal of Microbiology and Biotechnology (Volume 9, Issue 1) |
| DOI | 10.11648/j.ijmb.20240901.11 |
| Page(s) | 1-6 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Pharmaco-Multi-Resistance, Antimicrobial Activity, Fungicide, Cassia Occidentatlis
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APA Style
Ngassaki, R., Ampa, R., Tchiyamba, P. L., Assiana, D. O. E., Ahombo, G. (2024). Evaluation of the Antimicrobial Activity of Cassia *Occidentalis Lin on Several Multi-Resistant Microbial Strains. International Journal of Microbiology and Biotechnology, 9(1), 1-6. https://doi.org/10.11648/j.ijmb.20240901.11
ACS Style
Ngassaki, R.; Ampa, R.; Tchiyamba, P. L.; Assiana, D. O. E.; Ahombo, G. Evaluation of the Antimicrobial Activity of Cassia *Occidentalis Lin on Several Multi-Resistant Microbial Strains. Int. J. Microbiol. Biotechnol. 2024, 9(1), 1-6. doi: 10.11648/j.ijmb.20240901.11
AMA Style
Ngassaki R, Ampa R, Tchiyamba PL, Assiana DOE, Ahombo G. Evaluation of the Antimicrobial Activity of Cassia *Occidentalis Lin on Several Multi-Resistant Microbial Strains. Int J Microbiol Biotechnol. 2024;9(1):1-6. doi: 10.11648/j.ijmb.20240901.11
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Download@article{10.11648/j.ijmb.20240901.11,
author = {Raoul Ngassaki and Raoul Ampa and Pierrette Lokanga Tchiyamba and Darrel Ornelle Elion Assiana and Gabriel Ahombo},
title = {Evaluation of the Antimicrobial Activity of Cassia *Occidentalis Lin on Several Multi-Resistant Microbial Strains},
journal = {International Journal of Microbiology and Biotechnology},
volume = {9},
number = {1},
pages = {1-6},
doi = {10.11648/j.ijmb.20240901.11},
url = {https://doi.org/10.11648/j.ijmb.20240901.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmb.20240901.11},
abstract = {The aim of this work is to assess the antimicrobial potential of cassia occidentalis flax (Caesalpiniaceae) leaf extracts on drug-resistant microbial strains, in order to bring phytotherapeutic prescriptions into line with the potential biological activities of the chemical constituents present. Aqueous and hydro-ethanolic extracts were prepared according to the methods of Zirihi and Kra (2003). The antimicrobial activities were determined by measuring the rate of inhibition of microbial growth, diffusion on a solid medium and dilution in a liquid medium. In addition, the mode of action of the active extracts was determined by the ratio of the minimum fungicidal concentration to the minimum inhibitory concentration (MFC/MIC). Aqueous and hydroalcoholic extracts from the leaves of C. occidentalis have been shown to have antimicrobial activity. These extracts inhibited the proliferation of C. albicans strains resistant to nystatin. The activity of the aqueous extracts was similar to that obtained with the hydroalcoholic extracts. However, both types of extract showed no significant efficacy against S. aureus, E. coli and K. pneumoniae strains at the doses used (200 mg/ml; 100 mg/ml and 50 mg/ml) in all the pharmacological tests repeated during this study.
},
year = {2024}
}
TY - JOUR T1 - Evaluation of the Antimicrobial Activity of Cassia *Occidentalis Lin on Several Multi-Resistant Microbial Strains AU - Raoul Ngassaki AU - Raoul Ampa AU - Pierrette Lokanga Tchiyamba AU - Darrel Ornelle Elion Assiana AU - Gabriel Ahombo Y1 - 2024/01/23 PY - 2024 N1 - https://doi.org/10.11648/j.ijmb.20240901.11 DO - 10.11648/j.ijmb.20240901.11 T2 - International Journal of Microbiology and Biotechnology JF - International Journal of Microbiology and Biotechnology JO - International Journal of Microbiology and Biotechnology SP - 1 EP - 6 PB - Science Publishing Group SN - 2578-9686 UR - https://doi.org/10.11648/j.ijmb.20240901.11 AB - The aim of this work is to assess the antimicrobial potential of cassia occidentalis flax (Caesalpiniaceae) leaf extracts on drug-resistant microbial strains, in order to bring phytotherapeutic prescriptions into line with the potential biological activities of the chemical constituents present. Aqueous and hydro-ethanolic extracts were prepared according to the methods of Zirihi and Kra (2003). The antimicrobial activities were determined by measuring the rate of inhibition of microbial growth, diffusion on a solid medium and dilution in a liquid medium. In addition, the mode of action of the active extracts was determined by the ratio of the minimum fungicidal concentration to the minimum inhibitory concentration (MFC/MIC). Aqueous and hydroalcoholic extracts from the leaves of C. occidentalis have been shown to have antimicrobial activity. These extracts inhibited the proliferation of C. albicans strains resistant to nystatin. The activity of the aqueous extracts was similar to that obtained with the hydroalcoholic extracts. However, both types of extract showed no significant efficacy against S. aureus, E. coli and K. pneumoniae strains at the doses used (200 mg/ml; 100 mg/ml and 50 mg/ml) in all the pharmacological tests repeated during this study. VL - 9 IS - 1 ER -
Laboratory of Cellular and Molecular Biology, Marien Ngouabi University, Brazzaville, Congo
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