Human immunodeficiency virus (HIV) is a lentivirus, a member of the retrovirus family, wich primarily invades the human immune system and causes immunodeficiency syndrome (AIDS). HIV infection is one of the major public health problems associated with blood transfusion. The objective of this study is to estimate prevalence and trend of HIV among blood donors in Republic of Congo. A retrospective cross-sectional study design was used to collect data from January 2016 to December 2022 among blood donors in republic of Congo. For each blood donor, data including age, sex and type of blood donation (volunteer or family/replacement) were collected during a predonation examination. Samples were tested for anti-HIV antibodies using a fourth-generation ELISA. Data were analyzed using SPSS v21 software with a significance level of p<0.05. A total of 520823 blood donors were enrolled and the overall prevalence of HIV was 2.35%. The trend of HIV infection has decreased from 2016 (3.6%) to 2022 (2.1%). The prevalence of HIV among male (2.5%) was higher than in female donors (1.8%). The age groups 31-45 years and family/replacement donors were the highest prevalence of HIV infection, with a statistically significant difference (P<0.05). This study shows that the prevalence of HIV infections among blood donors remains high and needs constant monitoring to evaluate prevention strategies to reduce the burden of transfusion-transmissible HIV infections.
| Published in | International Journal of HIV/AIDS Prevention, Education and Behavioural Science (Volume 9, Issue 2) |
| DOI | 10.11648/j.ijhpebs.20230902.14 |
| Page(s) | 59-62 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Blood Donor, HIV, Prevalence, Transfusion
| [1] | World Health Organization. (2023). Global HIV & AIDS statistic: People Living with HIV by WHO region 2022. Available from: https://www.unaids.org/en/resources/fact-sheet. [Accessed 30 August 2023]. |
| [2] | Zhao, J., Chang, L., Wang, L. (2019). Nucleic acid testing and molecular characterization of HIV infections. European Journal of Clinical Microbiology & Infectious Diseases, 38; 829-842. |
| [3] | Shaw, G. M., Hunter, E. (2012). HIV transmission. Cold Spring Harbor perspectives in medicine 2(11): 1-23. |
| [4] | Baggaley, R. F., Boily, M. C., White, R. G., Alary, M. (2006). Risk of HIV-1 transmission for parenteral exposure and blood transfusion: a systematic review and meta-analysis. AIDS, 20(6): 805-812. |
| [5] | Allain, J. P., Stramer, S. L., Carneiro-Proietti, A. B. F., Martins, M. L., Da Silva, S. L., Ribeiro, M., Reesink, H. W. (2009). Transfusion-transmitted infectious diseases. Biologicals, 37(2): 71-77. |
| [6] | Kaur, P., & Basu, S. (2005). Transfusion-transmitted infections: Existing and emerging pathogens. Journal of postgraduate medicine, 51(2): 146-51. |
| [7] | Van Den Berg, K., Van Hasselt, J., Bloch, E., Crookes, R., Kelley, J., Berger, J., Bird, A. (2012). A review of the use of blood and blood products in HIV-infected patients. Southern African journal of HIV medicine 13(2): 87-104. |
| [8] | World Health Organization. (2016). Global Status Report on Blood Safety and Availability 2016. Available from: http://apps.who.int/bookorders. Accessed August 20 2023. |
| [9] | Allain JP, Owusu-Ofori, S. Bates, I. (2004). Blood transfusion in sub-Saharan Africa. Transfusion Alternatives in Transfusion Medicine, 6(1): 16–23. |
| [10] | Jayaraman S, Chalabi Z, Perel P, Guerriero C, Roberts I. (2010). The risk of transfusion-transmitted infections in sub-Saharan Africa. Transfusion, 50(2): 433–42. |
| [11] | Tagny CT, Mbanya D, Tapko JB, Lefrère JJ. (2008). Blood safety in sub-Saharan Africa: a multi-factorial problem. Transfusion, 48(6): 1256–61. |
| [12] | Enquête de Séroprévalence et sur les Indicateurs du Sida au Congo (ESISC-I). (2009). http://www.cnsee.org/pdf/RapSyntESISC.pdf. [Accessed 14 November 2023]. |
| [13] | Arsène Bikoué, Brunel M Angounda, Boris Bakoua-Soba, Jean Pierre Pambou, Félicité Dolama and Didier Boungou-Mpélé. (2021). Frequency of Human Immunodeficiency Virus, Hepatitis B/C Viruses, And Treponema pallidum Infections Among Blood Donors in Republic of Congo: A Ten Years Retrospective Study. J HIV AIDS Infect Dis 8: 1-11. |
| [14] | Senosy, S. A. (2015). Prevalence of HIV among blood donors at beni-suef university hospital blood bank, Egypt. The Journal of the Egyptian Public Health Association, 90(4): 157-160. |
| [15] | Pessoni, L. L., Aquino, É. C. D., Alcântara, K. C. D. (2019). Prevalence and trends in transfusion-transmissible infections among blood donors in Brazil from 2010 to 2016. Hematology, transfusion and cell therapy, 41: 310-315. |
| [16] | Song, Y., Bian, Y., Petzold, M., Ung, C. O. L. (2014). Prevalence and trend of major transfusion-transmissible infections among blood donors in Western China, 2005 through 2010. PloS one 9(4): 1-6. |
| [17] | Boushab, B. M., Limame, O. C. M. M., Zahra, F. M. F., Mamoudou, S., Darnycka, B. M. R., Saliou, S. M. (2017). Estimation of seroprevalence of HIV, hepatitis B and C virus and syphilis among blood donors in the hospital of Aïoun, Mauritania. Pan African Medical Journal, 28(1): 145-145. |
| [18] | Noubiap, J. J. N., Joko, W. Y. A., Nansseu, J. R. N., Tene, U. G., Siaka, C. (2013). Sero-epidemiology of human immunodeficiency virus, hepatitis B and C viruses, and syphilis infections among first-time blood donors in Edéa, Cameroon. International Journal of Infectious Diseases, 17(10): 832-837. |
| [19] | Xie, D. D., Li, J., Chen, J. T., Eyi, U. M., Matesa, R. A., Obono, M. M. O., Lin, M. (2015). Seroprevalence of human immunodeficiency virus, hepatitis B virus, hepatitis C virus, and Treponema pallidum infections among blood donors on Bioko Island, Equatorial Guinea. PloS one, 10(10): 1-9. |
| [20] | Lokpo, S. Y., Dakorah, M. P., Norgbe, G. K., Osei-Yeboah, J., Adzakpah, G., Sarsah, I., Amoah, P. (2017). The burden and trend of blood-borne pathogens among asymptomatic adult population in Akwatia: a retrospective study at the St. Dominic Hospital, Ghana. Journal of Tropical Medicine, 2017: 1-8. |
| [21] | Stokx J, Gillet P, De Weggheleire A, Casas EC, Maendaenda R, Beulane AJ, Bottieau E. (2011) Seroprevalence of transfusion-transmissible infections and evaluation of the pre-donation screening performance at the Provincial Hospital of Tete, Mozambique. BMC infectious diseases, 11: 1-8. |
| [22] | Wongjarupong, N., Oli, S., Sanou, M., Djigma, F., Koumare, A. K., Yonli, A. T., Nagalo, B. M. (2021). Distribution and incidence of blood-borne infection among blood donors from regional transfusion centers in Burkina Faso: A comprehensive study. The American Journal of Tropical Medicine and Hygiene, 104(4): 1577-1581. |
| [23] | Keleta, Y. T., Achila, O. O., Haile, A. W., Gebrecherkos, B. H., Tesfaldet, D. T., Teklu, K. S., Ghedel, S. T. (2019). Seroprevalence of transfusion transmitted infections among blood donors in Gash Barka Zonal Blood Transfusion Center, Barentu, Eritrea, 2014 through 2017. BMC hematology, 19(1): 1-9. |
| [24] | Tagny, C. T., Owusu-Ofori, S., Mbanya, D., Deneys, V. (2010). The blood donor in sub-Saharan Africa: a review. Transfusion Medicine, 20(1): 1-10. |
| [25] | Al-Nafakh, R. T., lteef Al-Fadhul, S. A., Al-Sherees, H. A. A., Al-Charrakh, A. H. (2019). Seroprevalence of HBV, HCV, and HIV among blood donors in main blood bank in Najaf Province, Iraq. Indian Journal of Public Health 10(4): 393-398. |
| [26] | Tapko, J. B., Mainuka, P., Diarra-Nama, A. J., World Health Organization. (2009). Status of blood safety in the WHO African region: report of the 2006 survey. |
APA Style
Monic Angounda, B., Oscar Mokono, S., Koukouikila-Koussounda, F., Soba Bakoua, B., Paola Louanga Nanitelamio, E., et al. (2023). Prevalence and Trends of HIV Infection Among Blood Donors in Republic of Congo from 2016 to 2022. International Journal of HIV/AIDS Prevention, Education and Behavioural Science, 9(2), 59-62. https://doi.org/10.11648/j.ijhpebs.20230902.14
ACS Style
Monic Angounda, B.; Oscar Mokono, S.; Koukouikila-Koussounda, F.; Soba Bakoua, B.; Paola Louanga Nanitelamio, E., et al. Prevalence and Trends of HIV Infection Among Blood Donors in Republic of Congo from 2016 to 2022. Int. J. HIV/AIDS Prev. Educ. Behav. Sci. 2023, 9(2), 59-62. doi: 10.11648/j.ijhpebs.20230902.14
AMA Style
Monic Angounda B, Oscar Mokono S, Koukouikila-Koussounda F, Soba Bakoua B, Paola Louanga Nanitelamio E, et al. Prevalence and Trends of HIV Infection Among Blood Donors in Republic of Congo from 2016 to 2022. Int J HIV/AIDS Prev Educ Behav Sci. 2023;9(2):59-62. doi: 10.11648/j.ijhpebs.20230902.14
Share This Article
Twitter
Linked In
Facebook
Copy
Download@article{10.11648/j.ijhpebs.20230902.14,
author = {Brunel Monic Angounda and Serge Oscar Mokono and Felix Koukouikila-Koussounda and Boris Soba Bakoua and Edwige Paola Louanga Nanitelamio and Geneviève Mbanzoulou Boukatou and Anicet Luc Magloire Boumba and Fabien Roch Niama},
title = {Prevalence and Trends of HIV Infection Among Blood Donors in Republic of Congo from 2016 to 2022},
journal = {International Journal of HIV/AIDS Prevention, Education and Behavioural Science},
volume = {9},
number = {2},
pages = {59-62},
doi = {10.11648/j.ijhpebs.20230902.14},
url = {https://doi.org/10.11648/j.ijhpebs.20230902.14},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijhpebs.20230902.14},
abstract = {Human immunodeficiency virus (HIV) is a lentivirus, a member of the retrovirus family, wich primarily invades the human immune system and causes immunodeficiency syndrome (AIDS). HIV infection is one of the major public health problems associated with blood transfusion. The objective of this study is to estimate prevalence and trend of HIV among blood donors in Republic of Congo. A retrospective cross-sectional study design was used to collect data from January 2016 to December 2022 among blood donors in republic of Congo. For each blood donor, data including age, sex and type of blood donation (volunteer or family/replacement) were collected during a predonation examination. Samples were tested for anti-HIV antibodies using a fourth-generation ELISA. Data were analyzed using SPSS v21 software with a significance level of pP<0.05). This study shows that the prevalence of HIV infections among blood donors remains high and needs constant monitoring to evaluate prevention strategies to reduce the burden of transfusion-transmissible HIV infections.
},
year = {2023}
}
TY - JOUR T1 - Prevalence and Trends of HIV Infection Among Blood Donors in Republic of Congo from 2016 to 2022 AU - Brunel Monic Angounda AU - Serge Oscar Mokono AU - Felix Koukouikila-Koussounda AU - Boris Soba Bakoua AU - Edwige Paola Louanga Nanitelamio AU - Geneviève Mbanzoulou Boukatou AU - Anicet Luc Magloire Boumba AU - Fabien Roch Niama Y1 - 2023/12/06 PY - 2023 N1 - https://doi.org/10.11648/j.ijhpebs.20230902.14 DO - 10.11648/j.ijhpebs.20230902.14 T2 - International Journal of HIV/AIDS Prevention, Education and Behavioural Science JF - International Journal of HIV/AIDS Prevention, Education and Behavioural Science JO - International Journal of HIV/AIDS Prevention, Education and Behavioural Science SP - 59 EP - 62 PB - Science Publishing Group SN - 2575-5765 UR - https://doi.org/10.11648/j.ijhpebs.20230902.14 AB - Human immunodeficiency virus (HIV) is a lentivirus, a member of the retrovirus family, wich primarily invades the human immune system and causes immunodeficiency syndrome (AIDS). HIV infection is one of the major public health problems associated with blood transfusion. The objective of this study is to estimate prevalence and trend of HIV among blood donors in Republic of Congo. A retrospective cross-sectional study design was used to collect data from January 2016 to December 2022 among blood donors in republic of Congo. For each blood donor, data including age, sex and type of blood donation (volunteer or family/replacement) were collected during a predonation examination. Samples were tested for anti-HIV antibodies using a fourth-generation ELISA. Data were analyzed using SPSS v21 software with a significance level of pP<0.05). This study shows that the prevalence of HIV infections among blood donors remains high and needs constant monitoring to evaluate prevention strategies to reduce the burden of transfusion-transmissible HIV infections. VL - 9 IS - 2 ER -
Faculty of Science and Technology, Marien Ngouabi University, Brazzaville, Congo; National Center of Blood Transfusion, Brazzaville, Congo
Information