Background Gastric cancer is a common gastrointestinal tumor with a high incidence and mortality rate, which is a serious threat to life and health; therefore, early diagnosis and interventions are particularly important. Currently, emerging gastric cancer-related targets Exosomes (EXOs) are being explored, (EXOs) are various bioactive substances, such as proteins, nucleic acids and lipids, actively secreted by various cells. It has been shown that exosomes are extensively involved in substance exchange and signal transduction between gastric cancer cells, affecting tumor proliferation and metastasis. Exosomes are biomarkers for the diagnosis and prognosis of gastric cancer, and are one of the hot spots in cancer research. Objective This paper mainly summarizes the research progress of related exosome detection methods and condenses a large amount of research evidence to systematically describe the characteristics of exosomes, related mechanisms and their diagnostic and therapeutic values in gastric cancer, hoping to provide new ideas and methods for the diagnosis and treatment of gastric cancer and new opportunities for better treatment of gastric cancer patients. Method Through extensive reading of relevant literature, we highly summarize relevant research mechanisms and diagnostic and therapeutic values, and explore and summarize the latest hot spots. Result and Conclusion EXOs as an emerging research hotspot, have extensive clinical value in gastric cancer progression. Using EXOs as key targets can provide new ideas and directions for the precise diagnosis and treatment of related GI tract tumors. It is also beneficial to the early diagnosis and of gastric cancer, and provides certain research prospects for the study of related inhibitory drugs.
Published in | International Journal of Gastroenterology (Volume 7, Issue 1) |
DOI | 10.11648/j.ijg.20230701.14 |
Page(s) | 25-31 |
Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
Copyright |
Copyright © The Author(s), 2023. Published by Science Publishing Group |
Exosomes, Gastric Cancer, Biomarker, Diagnosis and Treatment Value
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APA Style
Zaibo Zhang. (2023). Mechanism and Therapeutic Value of Exosomes in Gastric Cancer. International Journal of Gastroenterology, 7(1), 25-31. https://doi.org/10.11648/j.ijg.20230701.14
ACS Style
Zaibo Zhang. Mechanism and Therapeutic Value of Exosomes in Gastric Cancer. Int. J. Gastroenterol. 2023, 7(1), 25-31. doi: 10.11648/j.ijg.20230701.14
AMA Style
Zaibo Zhang. Mechanism and Therapeutic Value of Exosomes in Gastric Cancer. Int J Gastroenterol. 2023;7(1):25-31. doi: 10.11648/j.ijg.20230701.14
@article{10.11648/j.ijg.20230701.14, author = {Zaibo Zhang}, title = {Mechanism and Therapeutic Value of Exosomes in Gastric Cancer}, journal = {International Journal of Gastroenterology}, volume = {7}, number = {1}, pages = {25-31}, doi = {10.11648/j.ijg.20230701.14}, url = {https://doi.org/10.11648/j.ijg.20230701.14}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijg.20230701.14}, abstract = {Background Gastric cancer is a common gastrointestinal tumor with a high incidence and mortality rate, which is a serious threat to life and health; therefore, early diagnosis and interventions are particularly important. Currently, emerging gastric cancer-related targets Exosomes (EXOs) are being explored, (EXOs) are various bioactive substances, such as proteins, nucleic acids and lipids, actively secreted by various cells. It has been shown that exosomes are extensively involved in substance exchange and signal transduction between gastric cancer cells, affecting tumor proliferation and metastasis. Exosomes are biomarkers for the diagnosis and prognosis of gastric cancer, and are one of the hot spots in cancer research. Objective This paper mainly summarizes the research progress of related exosome detection methods and condenses a large amount of research evidence to systematically describe the characteristics of exosomes, related mechanisms and their diagnostic and therapeutic values in gastric cancer, hoping to provide new ideas and methods for the diagnosis and treatment of gastric cancer and new opportunities for better treatment of gastric cancer patients. Method Through extensive reading of relevant literature, we highly summarize relevant research mechanisms and diagnostic and therapeutic values, and explore and summarize the latest hot spots. Result and Conclusion EXOs as an emerging research hotspot, have extensive clinical value in gastric cancer progression. Using EXOs as key targets can provide new ideas and directions for the precise diagnosis and treatment of related GI tract tumors. It is also beneficial to the early diagnosis and of gastric cancer, and provides certain research prospects for the study of related inhibitory drugs.}, year = {2023} }
TY - JOUR T1 - Mechanism and Therapeutic Value of Exosomes in Gastric Cancer AU - Zaibo Zhang Y1 - 2023/05/17 PY - 2023 N1 - https://doi.org/10.11648/j.ijg.20230701.14 DO - 10.11648/j.ijg.20230701.14 T2 - International Journal of Gastroenterology JF - International Journal of Gastroenterology JO - International Journal of Gastroenterology SP - 25 EP - 31 PB - Science Publishing Group SN - 2640-169X UR - https://doi.org/10.11648/j.ijg.20230701.14 AB - Background Gastric cancer is a common gastrointestinal tumor with a high incidence and mortality rate, which is a serious threat to life and health; therefore, early diagnosis and interventions are particularly important. Currently, emerging gastric cancer-related targets Exosomes (EXOs) are being explored, (EXOs) are various bioactive substances, such as proteins, nucleic acids and lipids, actively secreted by various cells. It has been shown that exosomes are extensively involved in substance exchange and signal transduction between gastric cancer cells, affecting tumor proliferation and metastasis. Exosomes are biomarkers for the diagnosis and prognosis of gastric cancer, and are one of the hot spots in cancer research. Objective This paper mainly summarizes the research progress of related exosome detection methods and condenses a large amount of research evidence to systematically describe the characteristics of exosomes, related mechanisms and their diagnostic and therapeutic values in gastric cancer, hoping to provide new ideas and methods for the diagnosis and treatment of gastric cancer and new opportunities for better treatment of gastric cancer patients. Method Through extensive reading of relevant literature, we highly summarize relevant research mechanisms and diagnostic and therapeutic values, and explore and summarize the latest hot spots. Result and Conclusion EXOs as an emerging research hotspot, have extensive clinical value in gastric cancer progression. Using EXOs as key targets can provide new ideas and directions for the precise diagnosis and treatment of related GI tract tumors. It is also beneficial to the early diagnosis and of gastric cancer, and provides certain research prospects for the study of related inhibitory drugs. VL - 7 IS - 1 ER -