The Effect of Chlorhexidine and Tea Polyphenols Mouthwash in Adolescent Gingivitis

Hai Tao Zhu; Wan Yun Lin; Mu Xiu Chen; Hong Yuan Tian; Ying Ying Li; Kashaf Naz; Zhu Ling Guo

doi:doi:10.11648/j.ijcm.20220604.11

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The Effect of Chlorhexidine and Tea Polyphenols Mouthwash in Adolescent Gingivitis

Hai Tao Zhu, Wan Yun Lin, Mu Xiu Chen, Hong Yuan Tian, Ying Ying Li, Kashaf Naz, Zhu Ling Guo

Published in International Journal of Chinese Medicine (Volume 6, Issue 4)

Received: 23 October 2022 Accepted: 11 November 2022 Published: 23 November 2022

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Abstract

Periodontal Disease is one of the common diseases of the oral cavity. It is not only common in adults, but also in children and adolescents. As the public recognition of health concepts is growing fast, oral health has been focused. Mouthwash plays an important role in the lives of people with periodontal disease by effectively inhibiting plaque and reducing the risk of getting periodontal disease. Adolescent gingivitis is a common periodontal disease in the adolescent population. At present, it has been recognized that periodontal disease is a multi-factor disease, among which dental plaque biofilm is the most important pathogenic factor. The bacteria and their products of dental plaque are indispensable initiating factors for periodontal disease, which directly or indirectly participate in the process of periodontal disease. The ideal mouthwash should be able to reduce the number of bacteria in the oral cavity, eliminate or reduce the microorganisms on the surface of the teeth and the oral cavity, and inhibit the accumulation of plaque on the gums, tissue pathogenic bacteria re-colonized in the teeth and periodontal pockets, and prevent the recurrence of gingivitis. By introducing the prevalence and pathogenesis of gingivitis in adolescence, we analyzed the effect of two types of mouthwash of chlorhexidine and tea polyphenols on the control of gingivitis plaque in adolescence and the mechanism of bacterial inhibition, as well as the effect on the hard and soft tissues of the oral cavity, and evaluated the clinical efficacy of chlorhexidine and tea polyphenols in the control of gingivitis in adolescence.

Published in	International Journal of Chinese Medicine (Volume 6, Issue 4)
DOI	10.11648/j.ijcm.20220604.11
Page(s)	52-58
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Tea Polyphenols, Chlorhexidine, Adolescent Gingivitis, Periodontal Disease, Gonadal Hormone

References

[1]	Feng Xiping. Oral health status of the Chinese population - Report of the fourth Chinese oral health epidemiological survey. Paper presented at: The 18th Annual Conference of the Chinese Society of Stomatology on Preventive Stomatology 2018; Xi'an, Shaanxi, China.
[2]	Page RC, Schroeder HE. Pathogenesis of inflammatory periodontal disease. A summary of current work. Lab Invest. Mar 1976; 34 (3): 235-249.
[3]	Chapple ILC, Mealey BL, Van Dyke TE, et al. Periodontal health and gingival diseases and conditions on an intact and a reduced periodontium: Consensus report of workgroup 1 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. J Clin Periodontol. Jun 2018; 45 Suppl 20: S68-s77.
[4]	Wojcicki CJ, Harper DS, Robinson PJ. Differences in periodontal disease-associated microorganisms of subgingival plaque in prepubertal, pubertal and postpubertal children. J Periodontol. Apr 1987; 58 (4): 219-223.
[5]	Delaney JE, Ratzan SK, Kornman KS. Subgingival microbiota associated with puberty: studies of pre-, circum-, and postpubertal human females. Pediatr Dent. Dec 1986; 8 (4): 268-275.
[6]	Nakagawa S, Machida Y, Nakagawa T, et al. Infection by Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans, and antibody responses at different ages in humans. J Periodontal Res. Jan 1994; 29 (1): 9-16.
[7]	Löe H. Periodontal changes in pregnancy. The Journal of periodontology. 1965; 36 (3): 209-217.
[8]	Kalkwarf KL. Effect of oral contraceptive therapy on gingival inflammation in humans. Journal of periodontology. 1978; 49 (11): 560-563.
[9]	Wang Yefei. Inhibitory effect of tea polyphenols (TP) on bacteria. Tea. 1994 (03): 37-41.
[10]	Ishihara N, Chu D-C, Akachi S, Juneja L. Improvement of intestinal microflora balance and prevention of digestive and respiratory organ diseases in calves by green tea extracts. Livestock Production Science. 2001; 68 (2-3): 217-229.
[11]	Tang, Yu-Fang, Gong, Zheng-Li. A preliminary study on the deodorization mechanism of tea extracts. Tea Letters. 2000 (03): 35-36.
[12]	You Shiqi, Hong Fangyao, Li Zheguang, Huang Ketai, Xu Yuan, Yang Xianqiang. Study on the prevention of caries by green tea polyphenols in China. Chinese Journal of Stomatology. 1993 (04): 197-199+254.
[13]	McNaught J. On the action of cold or lukewarm tea on Bacillus typhosus. BMJ Military Health. 1906; 7 (4): 372-373.
[14]	Shen T, Khor SC, Zhou F, et al. Chemoprevention by lipid-soluble tea polyphenols in diethylnitrosamine/phenobarbital-induced hepatic pre-cancerous lesions. Anticancer research. 2014; 34 (2): 683-693.
[15]	Sudano Roccaro A, Blanco AR, Giuliano F, Rusciano D, Enea V. Epigallocatechin-gallate enhances the activity of tetracycline in staphylococci by inhibiting its efflux from bacterial cells. Antimicrob Agents Chemother. Jun 2004; 48 (6): 1968-1973.
[16]	Hisano M, Yamaguchi K, Inoue Y, et al. Inhibitory effect of catechin against the superantigen staphylococcal enterotoxin B (SEB). Arch Dermatol Res. Sep 2003; 295 (5): 183-189.
[17]	Xu X, Zhou XD, Wu CD. The tea catechin epigallocatechin gallate suppresses cariogenic virulence factors of Streptococcus mutans. Antimicrob Agents Chemother. Mar 2011; 55 (3): 1229-1236.
[18]	Sirk TW, Brown EF, Friedman M, Sum AK. Molecular binding of catechins to biomembranes: relationship to biological activity. J Agric Food Chem. Aug 12 2009; 57 (15): 6720-6728.
[19]	Sirk TW, Brown EF, Sum AK, Friedman M. Molecular dynamics study on the biophysical interactions of seven green tea catechins with lipid bilayers of cell membranes. J Agric Food Chem. Sep 10 2008; 56 (17): 7750-7758.
[20]	Sharma A, Gupta S, Sarethy IP, Dang S, Gabrani R. Green tea extract: possible mechanism and antibacterial activity on skin pathogens. Food Chem. Nov 15 2012; 135 (2): 672-675.
[21]	Gradisar H, Pristovsek P, Plaper A, Jerala R. Green tea catechins inhibit bacterial DNA gyrase by interaction with its ATP binding site. J Med Chem. Jan 25 2007; 50 (2): 264-271.
[22]	Akagawa M, Shigemitsu T, Suyama K. Production of hydrogen peroxide by polyphenols and polyphenol-rich beverages under quasi-physiological conditions. Biosci Biotechnol Biochem. Dec 2003; 67 (12): 2632-2640.
[23]	Arakawa H, Maeda M, Okubo S, Shimamura T. Role of hydrogen peroxide in bactericidal action of catechin. Biological and Pharmaceutical Bulletin. 2004; 27 (3): 277-281.
[24]	Wu DH, Guan ZEM, Li YAD. Study on the treatment of juvenile gingivitis with compound tea polyphenol rinse. Paper presented at: The First Annual Meeting of the General Practice Stomatology Committee of the Chinese Society of Stomatology 2009; Tianjin, China.
[25]	Wang P, Ji P, Luo QW, Zhang W, Tang M. The effect of a compound tea polyphenol rinse on subgingival flora and gingival sulcus endotoxin levels in periodontitis patients. Effect of compound tea polyphenol rinse on subgingival flora and gingival sulcus fluid endotoxin levels in patients with periodontitis. Journal of Chongqing Medical University. 2007 (01): 72-75.
[26]	Gillette W. Re: Antibiotics and periodontal disease. J Periodontol. Jul 1996; 67 (7): 726.
[27]	Xiao Yue, Liu Tianjia, Huang Zhengwei, Zhou Xuedong, Zhan Ling, Li Jiyao. Experimental study on the effect of tea polyphenols on the caries-causing power of oral bacteria. Guangdong Dental Disease Control. 2002 (01): 4-6.
[28]	Yang Hailun, Liu Xiaoxiang, Zhu Junli, Li Jianrong. Research progress on the antibacterial properties of tea polyphenols. Food Industry Science and Technology. 2015; 36 (21): 385-389.
[29]	Gilbert P, Moore LE. Cationic antiseptics: diversity of action under a common epithet. J Appl Microbiol. 2005; 99 (4): 703-715.
[30]	Cieplik F, Jakubovics NS, Buchalla W, Maisch T, Hellwig E, Al-Ahmad A. Resistance Toward Chlorhexidine in Oral Bacteria - Is There Cause for Concern? Front Microbiol. 2019; 10: 587.
[31]	Janakiram C, Venkitachalam R, Fontelo P, Iafolla TJ, Dye BA. Effectiveness of herbal oral care products in reducing dental plaque & gingivitis - a systematic review and meta-analysis. BMC Complement Med Ther. Feb 11 2020; 20 (1): 43.
[32]	Wade WG. The oral microbiome in health and disease. Pharmacol Res. Mar 2013; 69 (1): 137-143.
[33]	Hoffmann T, Bruhn G, Richter S, Netuschil L, Brecx M. Clinical controlled study on plaque and gingivitis reduction under long-term use of low-dose chlorhexidine solutions in a population exhibiting good oral hygiene. Clin Oral Investig. Jun 2001; 5 (2): 89-95.
[34]	Roberts WR, Addy M. Comparison of the in vivo and in vitro antibacterial properties of antiseptic mouthrinses containing chlorhexidine, alexidine, cetyl pyridinium chloride and hexetidine. Relevance to mode of action. J Clin Periodontol. Aug 1981; 8 (4): 295-310.
[35]	Hajishengallis G, Liang S, Payne MA, et al. Low-abundance biofilm species orchestrates inflammatory periodontal disease through the commensal microbiota and complement. Cell Host Microbe. Nov 17 2011; 10 (5): 497-506.
[36]	Bartold PM, Van Dyke TE. An appraisal of the role of specific bacteria in the initial pathogenesis of periodontitis. J Clin Periodontol. Jan 2019; 46 (1): 6-11.
[37]	James P, Worthington HV, Parnell C, et al. Chlorhexidine mouthrinse as an adjunctive treatment for gingival health. Cochrane Database Syst Rev. Mar 31 2017; 3 (3): Cd008676.
[38]	Tribble GD, Angelov N, Weltman R, et al. Frequency of Tongue Cleaning Impacts the Human Tongue Microbiome Composition and Enterosalivary Circulation of Nitrate. Front Cell Infect Microbiol. 2019; 9: 39.
[39]	Hyde ER, Luk B, Cron S, et al. Characterization of the rat oral microbiome and the effects of dietary nitrate. Free Radic Biol Med. Dec 2014; 77: 249-257.
[40]	Bescos R, Ashworth A, Cutler C, et al. Effects of Chlorhexidine mouthwash on the oral microbiome. Sci Rep. Mar 24 2020; 10 (1): 5254.
[41]	Chatzigiannidou I, Teughels W, Van de Wiele T, Boon N. Oral biofilms exposure to chlorhexidine results in altered microbial composition and metabolic profile. NPJ Biofilms Microbiomes. Mar 20 2020; 6 (1): 13.
[42]	Mayer FL, Wilson D, Hube B. Candida albicans pathogenicity mechanisms. Virulence. Feb 15 2013; 4 (2): 119-128.
[43]	LaFleur MD, Kumamoto CA, Lewis K. Candida albicans biofilms produce antifungal-tolerant persister cells. Antimicrob Agents Chemother. Nov 2006; 50 (11): 3839-3846.
[44]	Samonis G, Gikas A, Anaissie EJ, et al. Prospective evaluation of effects of broad-spectrum antibiotics on gastrointestinal yeast colonization of humans. Antimicrob Agents Chemother. Jan 1993; 37 (1): 51-53.
[45]	Sam QH, Chang MW, Chai LY. The Fungal Mycobiome and Its Interaction with Gut Bacteria in the Host. Int J Mol Sci. Feb 4 2017; 18 (2).
[46]	Barnes RA. Early diagnosis of fungal infection in immunocompromised patients. J Antimicrob Chemother. Jan 2008; 61 Suppl 1: i3-6.
[47]	Franco Neto CA, Parolo CC, Rösing CK, Maltz M. Comparative analysis of the effect of two chlorhexidine mouthrinses on plaque accumulation and gingival bleeding. Braz Oral Res. Apr-Jun 2008; 22 (2): 139-144.
[48]	Keijser JA, Verkade H, Timmerman MF, Van der Weijden FA. Comparison of 2 commercially available chlorhexidine mouthrinses. J Periodontol. Feb 2003; 74 (2): 214-218.
[49]	Van Strydonck DA, Timmerman MF, van der Velden U, van der Weijden GA. Plaque inhibition of two commercially available chlorhexidine mouthrinses. J Clin Periodontol. Mar 2005; 32 (3): 305-309.
[50]	Cumming BR, Löe H. Optimal dosage and method of delivering chlorhexidine solutions for the inhibition of dental plaque. J Periodontal Res. 1973; 8 (2): 57-62.
[51]	Agerbaek N, Melsen B, Rölla G. Application of chlorhexidine by oral irrigation systems. Scand J Dent Res. Sep 1975; 83 (5): 284-287.
[52]	Jenkins S, Addy M, Newcombe RG. Dose response of chlorhexidine against plaque and comparison with triclosan. J Clin Periodontol. Apr 1994; 21 (4): 250-255.
[53]	Flötra L, Gjermo P, Rölla G, Waerhaug J. Side effects of chlorhexidine mouth washes. Scand J Dent Res. 1971; 79 (2): 119-125.
[54]	Haydari M, Bardakci AG, Koldsland OC, Aass AM, Sandvik L, Preus HR. Comparing the effect of 0.06% -, 0.12% and 0.2% Chlorhexidine on plaque, bleeding and side effects in an experimental gingivitis model: a parallel group, double masked randomized clinical trial. BMC Oral Health. Aug 18 2017; 17 (1): 118.
[55]	Turesky S, Gilmore ND, Glickman I. Reduced plaque formation by the chloromethyl analogue of victamine C. J Periodontol. Jan 1970; 41 (1): 41-43.
[56]	Löe H. The Gingival Index, the Plaque Index and the Retention Index Systems. J Periodontol. Nov-Dec 1967; 38 (6): Suppl: 610-616.
[57]	Rupp ME. Do chlorhexidine patient baths prevent catheter-associated urinary tract infections? Lancet Infect Dis. Jan 2016; 16 (1): 8-9.
[58]	Saleem HG, Seers CA, Sabri AN, Reynolds EC. Dental plaque bacteria with reduced susceptibility to chlorhexidine are multidrug resistant. BMC Microbiol. Sep 15 2016; 16: 214.
[59]	Mazur M, Ndokaj A, Jedlinski M, Ardan R, Bietolini S, Ottolenghi L. Impact of Green Tea (Camellia Sinensis) on periodontitis and caries. Systematic review and meta-analysis. Jpn Dent Sci Rev. 2021 Nov; 57: 1-11.

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APA Style

Hai Tao Zhu, Wan Yun Lin, Mu Xiu Chen, Hong Yuan Tian, Ying Ying Li, et al. (2022). The Effect of Chlorhexidine and Tea Polyphenols Mouthwash in Adolescent Gingivitis. International Journal of Chinese Medicine, 6(4), 52-58. https://doi.org/10.11648/j.ijcm.20220604.11

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ACS Style

Hai Tao Zhu; Wan Yun Lin; Mu Xiu Chen; Hong Yuan Tian; Ying Ying Li, et al. The Effect of Chlorhexidine and Tea Polyphenols Mouthwash in Adolescent Gingivitis. Int. J. Chin. Med. 2022, 6(4), 52-58. doi: 10.11648/j.ijcm.20220604.11

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AMA Style

Hai Tao Zhu, Wan Yun Lin, Mu Xiu Chen, Hong Yuan Tian, Ying Ying Li, et al. The Effect of Chlorhexidine and Tea Polyphenols Mouthwash in Adolescent Gingivitis. Int J Chin Med. 2022;6(4):52-58. doi: 10.11648/j.ijcm.20220604.11

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@article{10.11648/j.ijcm.20220604.11,
  author = {Hai Tao Zhu and Wan Yun Lin and Mu Xiu Chen and Hong Yuan Tian and Ying Ying Li and Kashaf Naz and Zhu Ling Guo},
  title = {The Effect of Chlorhexidine and Tea Polyphenols Mouthwash in Adolescent Gingivitis},
  journal = {International Journal of Chinese Medicine},
  volume = {6},
  number = {4},
  pages = {52-58},
  doi = {10.11648/j.ijcm.20220604.11},
  url = {https://doi.org/10.11648/j.ijcm.20220604.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcm.20220604.11},
  abstract = {Periodontal Disease is one of the common diseases of the oral cavity. It is not only common in adults, but also in children and adolescents. As the public recognition of health concepts is growing fast, oral health has been focused. Mouthwash plays an important role in the lives of people with periodontal disease by effectively inhibiting plaque and reducing the risk of getting periodontal disease. Adolescent gingivitis is a common periodontal disease in the adolescent population. At present, it has been recognized that periodontal disease is a multi-factor disease, among which dental plaque biofilm is the most important pathogenic factor. The bacteria and their products of dental plaque are indispensable initiating factors for periodontal disease, which directly or indirectly participate in the process of periodontal disease. The ideal mouthwash should be able to reduce the number of bacteria in the oral cavity, eliminate or reduce the microorganisms on the surface of the teeth and the oral cavity, and inhibit the accumulation of plaque on the gums, tissue pathogenic bacteria re-colonized in the teeth and periodontal pockets, and prevent the recurrence of gingivitis. By introducing the prevalence and pathogenesis of gingivitis in adolescence, we analyzed the effect of two types of mouthwash of chlorhexidine and tea polyphenols on the control of gingivitis plaque in adolescence and the mechanism of bacterial inhibition, as well as the effect on the hard and soft tissues of the oral cavity, and evaluated the clinical efficacy of chlorhexidine and tea polyphenols in the control of gingivitis in adolescence.},
 year = {2022}
}

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TY  - JOUR
T1  - The Effect of Chlorhexidine and Tea Polyphenols Mouthwash in Adolescent Gingivitis
AU  - Hai Tao Zhu
AU  - Wan Yun Lin
AU  - Mu Xiu Chen
AU  - Hong Yuan Tian
AU  - Ying Ying Li
AU  - Kashaf Naz
AU  - Zhu Ling Guo
Y1  - 2022/11/23
PY  - 2022
N1  - https://doi.org/10.11648/j.ijcm.20220604.11
DO  - 10.11648/j.ijcm.20220604.11
T2  - International Journal of Chinese Medicine
JF  - International Journal of Chinese Medicine
JO  - International Journal of Chinese Medicine
SP  - 52
EP  - 58
PB  - Science Publishing Group
SN  - 2578-9473
UR  - https://doi.org/10.11648/j.ijcm.20220604.11
AB  - Periodontal Disease is one of the common diseases of the oral cavity. It is not only common in adults, but also in children and adolescents. As the public recognition of health concepts is growing fast, oral health has been focused. Mouthwash plays an important role in the lives of people with periodontal disease by effectively inhibiting plaque and reducing the risk of getting periodontal disease. Adolescent gingivitis is a common periodontal disease in the adolescent population. At present, it has been recognized that periodontal disease is a multi-factor disease, among which dental plaque biofilm is the most important pathogenic factor. The bacteria and their products of dental plaque are indispensable initiating factors for periodontal disease, which directly or indirectly participate in the process of periodontal disease. The ideal mouthwash should be able to reduce the number of bacteria in the oral cavity, eliminate or reduce the microorganisms on the surface of the teeth and the oral cavity, and inhibit the accumulation of plaque on the gums, tissue pathogenic bacteria re-colonized in the teeth and periodontal pockets, and prevent the recurrence of gingivitis. By introducing the prevalence and pathogenesis of gingivitis in adolescence, we analyzed the effect of two types of mouthwash of chlorhexidine and tea polyphenols on the control of gingivitis plaque in adolescence and the mechanism of bacterial inhibition, as well as the effect on the hard and soft tissues of the oral cavity, and evaluated the clinical efficacy of chlorhexidine and tea polyphenols in the control of gingivitis in adolescence.
VL  - 6
IS  - 4
ER  -

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Author Information

Hai Tao Zhu

School of Dentistry, Hainan Medical University, Haikou, PR China
Wan Yun Lin

School of Dentistry, Hainan Medical University, Haikou, PR China
Mu Xiu Chen

School of Dentistry, Hainan Medical University, Haikou, PR China
Hong Yuan Tian

School of Dentistry, Hainan Medical University, Haikou, PR China
Ying Ying Li

School of Dentistry, Hainan Medical University, Haikou, PR China
Kashaf Naz

School of International Education, Hainan Medical University, Haikou, PR China
Zhu Ling Guo

School of Dentistry, Hainan Medical University, Haikou, PR China

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APA Style

Hai Tao Zhu, Wan Yun Lin, Mu Xiu Chen, Hong Yuan Tian, Ying Ying Li, et al. (2022). The Effect of Chlorhexidine and Tea Polyphenols Mouthwash in Adolescent Gingivitis. International Journal of Chinese Medicine, 6(4), 52-58. https://doi.org/10.11648/j.ijcm.20220604.11

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ACS Style

Hai Tao Zhu; Wan Yun Lin; Mu Xiu Chen; Hong Yuan Tian; Ying Ying Li, et al. The Effect of Chlorhexidine and Tea Polyphenols Mouthwash in Adolescent Gingivitis. Int. J. Chin. Med. 2022, 6(4), 52-58. doi: 10.11648/j.ijcm.20220604.11

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AMA Style

Hai Tao Zhu, Wan Yun Lin, Mu Xiu Chen, Hong Yuan Tian, Ying Ying Li, et al. The Effect of Chlorhexidine and Tea Polyphenols Mouthwash in Adolescent Gingivitis. Int J Chin Med. 2022;6(4):52-58. doi: 10.11648/j.ijcm.20220604.11

Copy | Download

@article{10.11648/j.ijcm.20220604.11,
  author = {Hai Tao Zhu and Wan Yun Lin and Mu Xiu Chen and Hong Yuan Tian and Ying Ying Li and Kashaf Naz and Zhu Ling Guo},
  title = {The Effect of Chlorhexidine and Tea Polyphenols Mouthwash in Adolescent Gingivitis},
  journal = {International Journal of Chinese Medicine},
  volume = {6},
  number = {4},
  pages = {52-58},
  doi = {10.11648/j.ijcm.20220604.11},
  url = {https://doi.org/10.11648/j.ijcm.20220604.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcm.20220604.11},
  abstract = {Periodontal Disease is one of the common diseases of the oral cavity. It is not only common in adults, but also in children and adolescents. As the public recognition of health concepts is growing fast, oral health has been focused. Mouthwash plays an important role in the lives of people with periodontal disease by effectively inhibiting plaque and reducing the risk of getting periodontal disease. Adolescent gingivitis is a common periodontal disease in the adolescent population. At present, it has been recognized that periodontal disease is a multi-factor disease, among which dental plaque biofilm is the most important pathogenic factor. The bacteria and their products of dental plaque are indispensable initiating factors for periodontal disease, which directly or indirectly participate in the process of periodontal disease. The ideal mouthwash should be able to reduce the number of bacteria in the oral cavity, eliminate or reduce the microorganisms on the surface of the teeth and the oral cavity, and inhibit the accumulation of plaque on the gums, tissue pathogenic bacteria re-colonized in the teeth and periodontal pockets, and prevent the recurrence of gingivitis. By introducing the prevalence and pathogenesis of gingivitis in adolescence, we analyzed the effect of two types of mouthwash of chlorhexidine and tea polyphenols on the control of gingivitis plaque in adolescence and the mechanism of bacterial inhibition, as well as the effect on the hard and soft tissues of the oral cavity, and evaluated the clinical efficacy of chlorhexidine and tea polyphenols in the control of gingivitis in adolescence.},
 year = {2022}
}

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TY  - JOUR
T1  - The Effect of Chlorhexidine and Tea Polyphenols Mouthwash in Adolescent Gingivitis
AU  - Hai Tao Zhu
AU  - Wan Yun Lin
AU  - Mu Xiu Chen
AU  - Hong Yuan Tian
AU  - Ying Ying Li
AU  - Kashaf Naz
AU  - Zhu Ling Guo
Y1  - 2022/11/23
PY  - 2022
N1  - https://doi.org/10.11648/j.ijcm.20220604.11
DO  - 10.11648/j.ijcm.20220604.11
T2  - International Journal of Chinese Medicine
JF  - International Journal of Chinese Medicine
JO  - International Journal of Chinese Medicine
SP  - 52
EP  - 58
PB  - Science Publishing Group
SN  - 2578-9473
UR  - https://doi.org/10.11648/j.ijcm.20220604.11
AB  - Periodontal Disease is one of the common diseases of the oral cavity. It is not only common in adults, but also in children and adolescents. As the public recognition of health concepts is growing fast, oral health has been focused. Mouthwash plays an important role in the lives of people with periodontal disease by effectively inhibiting plaque and reducing the risk of getting periodontal disease. Adolescent gingivitis is a common periodontal disease in the adolescent population. At present, it has been recognized that periodontal disease is a multi-factor disease, among which dental plaque biofilm is the most important pathogenic factor. The bacteria and their products of dental plaque are indispensable initiating factors for periodontal disease, which directly or indirectly participate in the process of periodontal disease. The ideal mouthwash should be able to reduce the number of bacteria in the oral cavity, eliminate or reduce the microorganisms on the surface of the teeth and the oral cavity, and inhibit the accumulation of plaque on the gums, tissue pathogenic bacteria re-colonized in the teeth and periodontal pockets, and prevent the recurrence of gingivitis. By introducing the prevalence and pathogenesis of gingivitis in adolescence, we analyzed the effect of two types of mouthwash of chlorhexidine and tea polyphenols on the control of gingivitis plaque in adolescence and the mechanism of bacterial inhibition, as well as the effect on the hard and soft tissues of the oral cavity, and evaluated the clinical efficacy of chlorhexidine and tea polyphenols in the control of gingivitis in adolescence.
VL  - 6
IS  - 4
ER  -

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