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Chondroxide Gel Manufactured by Herbion Pakistan (Pvt.) Ltd in Patients with Osteoarthritis, Rheumatoid Arthritis, Cervical Spondylosis, and Frozen Shoulder

Received: 5 September 2022    Accepted: 30 March 2023    Published: 11 July 2023
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Abstract

Aims and Objective: Chondroxide gel is used topically in osteoarthritis, rheumatoid arthritis, cervical spondylosis, and frozen shoulder. This small-scale clinical survey was conducted to determine the safety and efficacy of the herbal product Chondroxide gel manufactured by Herbion Pakistan (Pvt.) Ltd. at Tulsi Medical Centre, Karachi, Pakistan. Introduction: Osteoarthritis is the most common disorder with joint pain and stiffness symptoms. Rheumatoid arthritis is a chronic inflammatory autoimmune disorder and another common reason for disability. At the same time, cervical spondylosis is a disease affecting the cervical spine, whereas a frozen shoulder often prolongs a disabling condition that can be managed by primary care. Method: This was a small-scale, open-labeled clinical survey. A total of 30 patients were enrolled in the study, out of which four patients got dropped out. 26 patients received Chondroxide gel. Statistical analysis was done by using the IBM SPSS 20. Results: Chondroxide gel was found safe and effective in treating osteoarthritis, rheumatoid arthritis, cervical spondylosis, and frozen shoulder and stated better response compared to the topical formulation available in the market. Conclusion: The results indicated improvement after applying the Chondroxide gel in patients with osteoarthritis, rheumatoid arthritis, cervical spondylosis, and frozen shoulder complaints and relieved external pain.

Published in International Journal of Clinical and Experimental Medical Sciences (Volume 9, Issue 4)
DOI 10.11648/j.ijcems.20230904.11
Page(s) 60-64
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Chondroxide Gel, Osteoarthritis, Rheumatoid Arthritis, Cervical Spondylosis, Frozen Shoulder

References
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[2] Arden, N. and M. C. Nevitt, Osteoarthritis: epidemiology. Best practice & research Clinical rheumatology, 2006. 20 (1): p. 3-25.
[3] Majithia, V. and S. A. Geraci, Rheumatoid arthritis: diagnosis and management. The American journal of medicine, 2007. 120 (11): p. 936-939.
[4] Hossain, S., Shamim, A., Saifuzzaman, M., Attiquzzaman, M., Hossain, G., & Raihan, O. (2020). Formulation and development of a topical combination cream for arthritis management. Tropical Journal of Pharmaceutical Research, 19 (6), 1125-1130.
[5] Lestini, W. F. and S. W. Wiesel, The pathogenesis of cervical spondylosis. Clinical orthopaedics and related research, 1989 (239): p. 69-93.
[6] Dias, R., S. Cutts, and S. Massoud, Frozen shoulder. Bmj, 2005. 331 (7530): p. 1453-1456.
[7] Lin, J., et al., Efficacy of topical non-steroidal anti-inflammatory drugs in the treatment of osteoarthritis: meta-analysis of randomised controlled trials. Bmj, 2004. 329 (7461): p. 324.
[8] Heyneman, C. A., C. Lawless-Liday, and G. C. Wall, Oral versus topical NSAIDs in rheumatic diseases. Drugs, 2000. 60 (3): p. 555-574.
[9] Vaile, J. H. and P. Davis, Topical NSAIDs for musculoskeletal conditions. Drugs, 1998. 56 (5): p. 783-799.
[10] Mazieres, B., et al., Chondroitin sulfate in osteoarthritis of the knee: a prospective, double blind, placebo controlled multicenter clinical study. The Journal of rheumatology, 2001. 28 (1): p. 173-181.
[11] Bana, G., et al., Chondroitin sulfate in the management of hip and knee osteoarthritis: an overview. Advances in Pharmacology, 2006. 53: p. 507-522.
[12] Wang, H., & Ma, B. (2022). Healthcare and scientific treatment of knee osteoarthritis. Journal of Healthcare Engineering, 2022.
[13] Wen, J., Li, H., Dai, H., Hua, S., Long, X., Li, H., ... & Xu, C. (2023). Intra-articular nanoparticles based therapies for osteoarthritis and rheumatoid arthritis management. Materials Today Bio, 100597.
[14] Zhang, Y., Gao, Z., Chao, S., Lu, W., & Zhang, P. (2022). Transdermal delivery of inflammatory factors regulated drugs for rheumatoid arthritis. Drug Delivery, 29 (1), 1934-1950.
[15] Rodríguez-Merchán, E. C., De la Corte-Rodríguez, H., & Román-Belmonte, J. M. (2020). Initial Treatment of Knee Osteoarthritis: Oral and Topical Drugs. Comprehensive Treatment of Knee Osteoarthritis: Recent Advances, 1-10.
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  • APA Style

    Saba Fatima, Ifrah Hasan, Muhammad Junaid. (2023). Chondroxide Gel Manufactured by Herbion Pakistan (Pvt.) Ltd in Patients with Osteoarthritis, Rheumatoid Arthritis, Cervical Spondylosis, and Frozen Shoulder. International Journal of Clinical and Experimental Medical Sciences, 9(4), 60-64. https://doi.org/10.11648/j.ijcems.20230904.11

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    ACS Style

    Saba Fatima; Ifrah Hasan; Muhammad Junaid. Chondroxide Gel Manufactured by Herbion Pakistan (Pvt.) Ltd in Patients with Osteoarthritis, Rheumatoid Arthritis, Cervical Spondylosis, and Frozen Shoulder. Int. J. Clin. Exp. Med. Sci. 2023, 9(4), 60-64. doi: 10.11648/j.ijcems.20230904.11

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    AMA Style

    Saba Fatima, Ifrah Hasan, Muhammad Junaid. Chondroxide Gel Manufactured by Herbion Pakistan (Pvt.) Ltd in Patients with Osteoarthritis, Rheumatoid Arthritis, Cervical Spondylosis, and Frozen Shoulder. Int J Clin Exp Med Sci. 2023;9(4):60-64. doi: 10.11648/j.ijcems.20230904.11

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  • @article{10.11648/j.ijcems.20230904.11,
      author = {Saba Fatima and Ifrah Hasan and Muhammad Junaid},
      title = {Chondroxide Gel Manufactured by Herbion Pakistan (Pvt.) Ltd in Patients with Osteoarthritis, Rheumatoid Arthritis, Cervical Spondylosis, and Frozen Shoulder},
      journal = {International Journal of Clinical and Experimental Medical Sciences},
      volume = {9},
      number = {4},
      pages = {60-64},
      doi = {10.11648/j.ijcems.20230904.11},
      url = {https://doi.org/10.11648/j.ijcems.20230904.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcems.20230904.11},
      abstract = {Aims and Objective: Chondroxide gel is used topically in osteoarthritis, rheumatoid arthritis, cervical spondylosis, and frozen shoulder. This small-scale clinical survey was conducted to determine the safety and efficacy of the herbal product Chondroxide gel manufactured by Herbion Pakistan (Pvt.) Ltd. at Tulsi Medical Centre, Karachi, Pakistan. Introduction: Osteoarthritis is the most common disorder with joint pain and stiffness symptoms. Rheumatoid arthritis is a chronic inflammatory autoimmune disorder and another common reason for disability. At the same time, cervical spondylosis is a disease affecting the cervical spine, whereas a frozen shoulder often prolongs a disabling condition that can be managed by primary care. Method: This was a small-scale, open-labeled clinical survey. A total of 30 patients were enrolled in the study, out of which four patients got dropped out. 26 patients received Chondroxide gel. Statistical analysis was done by using the IBM SPSS 20. Results: Chondroxide gel was found safe and effective in treating osteoarthritis, rheumatoid arthritis, cervical spondylosis, and frozen shoulder and stated better response compared to the topical formulation available in the market. Conclusion: The results indicated improvement after applying the Chondroxide gel in patients with osteoarthritis, rheumatoid arthritis, cervical spondylosis, and frozen shoulder complaints and relieved external pain.},
     year = {2023}
    }
    

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  • TY  - JOUR
    T1  - Chondroxide Gel Manufactured by Herbion Pakistan (Pvt.) Ltd in Patients with Osteoarthritis, Rheumatoid Arthritis, Cervical Spondylosis, and Frozen Shoulder
    AU  - Saba Fatima
    AU  - Ifrah Hasan
    AU  - Muhammad Junaid
    Y1  - 2023/07/11
    PY  - 2023
    N1  - https://doi.org/10.11648/j.ijcems.20230904.11
    DO  - 10.11648/j.ijcems.20230904.11
    T2  - International Journal of Clinical and Experimental Medical Sciences
    JF  - International Journal of Clinical and Experimental Medical Sciences
    JO  - International Journal of Clinical and Experimental Medical Sciences
    SP  - 60
    EP  - 64
    PB  - Science Publishing Group
    SN  - 2469-8032
    UR  - https://doi.org/10.11648/j.ijcems.20230904.11
    AB  - Aims and Objective: Chondroxide gel is used topically in osteoarthritis, rheumatoid arthritis, cervical spondylosis, and frozen shoulder. This small-scale clinical survey was conducted to determine the safety and efficacy of the herbal product Chondroxide gel manufactured by Herbion Pakistan (Pvt.) Ltd. at Tulsi Medical Centre, Karachi, Pakistan. Introduction: Osteoarthritis is the most common disorder with joint pain and stiffness symptoms. Rheumatoid arthritis is a chronic inflammatory autoimmune disorder and another common reason for disability. At the same time, cervical spondylosis is a disease affecting the cervical spine, whereas a frozen shoulder often prolongs a disabling condition that can be managed by primary care. Method: This was a small-scale, open-labeled clinical survey. A total of 30 patients were enrolled in the study, out of which four patients got dropped out. 26 patients received Chondroxide gel. Statistical analysis was done by using the IBM SPSS 20. Results: Chondroxide gel was found safe and effective in treating osteoarthritis, rheumatoid arthritis, cervical spondylosis, and frozen shoulder and stated better response compared to the topical formulation available in the market. Conclusion: The results indicated improvement after applying the Chondroxide gel in patients with osteoarthritis, rheumatoid arthritis, cervical spondylosis, and frozen shoulder complaints and relieved external pain.
    VL  - 9
    IS  - 4
    ER  - 

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Author Information
  • Medical Affairs and Training Department, Herbion Pakistan (Pvt.) Ltd., Karachi, Pakistan

  • Medical Affairs and Training Department, Herbion Pakistan (Pvt.) Ltd., Karachi, Pakistan

  • Medical Affairs and Training Department, Herbion Pakistan (Pvt.) Ltd., Karachi, Pakistan

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