Hydroxyapatite: A Comprehensive Review of Its Properties, Applications, and Future Trends

Ibraheem Redhwi; Ahmad Fallatah; Fahad Alshabona

doi:doi:10.11648/j.ijbmr.20241201.11

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Hydroxyapatite: A Comprehensive Review of Its Properties, Applications, and Future Trends

Ibraheem Redhwi

, Ahmad Fallatah

, Fahad Alshabona^*

Published in International Journal of Biomedical Materials Research (Volume 12, Issue 1)

Received: 7 October 2024 Accepted: 22 October 2024 Published: 20 November 2024

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Abstract

Hydroxyapatite (HA) is a bioactive ceramic material which has given an important attention in the biomedical field because of its high biocompatibility and structural similarity to human’s and mammal’s bone. This study provides a comprehensive exploration of HA's properties, applications, and future trends, accentuating its potential in several domains beyond its traditional uses in bone and dental implants. HA's unique characteristics, including its osteoconductivity and ability to promote bone regeneration, make it an ideal candidate for advanced tissue engineering and drug delivery systems. The review discusses the fundamental properties of HA, such as its chemical composition, physical structure, and biological compatibility, which collectively contribute to its effectiveness in medical applications. Furthermore, ongoing research is highlighted, particularly in the development of nanostructured HA and composite materials, aimed at enhancing its mechanical properties and expanding its use in complex medical scenarios. Additionally, the implications of emerging technologies, specifically 3D printing and the potential of 4D printing, are examined. These innovations allow for the creation of personalized scaffolds tailored to individual patient needs, enhancing the prospects for regenerative medicine. The versatility of HA is further illustrated through its applications in non-medical fields, including environmental remediation and as a component in fertilizers and water purification systems. Overall, this review underscores the critical role that hydroxyapatite plays in bridging the gap between biological and synthetic materials. By synthesizing current knowledge and identifying future research directions, this work aims to pave the way for further advancements in the use of HA across various biomedical and industrial contexts, ultimately contributing to improved health outcomes and innovative material solutions.

Published in	International Journal of Biomedical Materials Research (Volume 12, Issue 1)
DOI	10.11648/j.ijbmr.20241201.11
Page(s)	1-6
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Hydroxyapatite, Biocompatible, Tissue Engineering, Drug Delivery System

References

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Cite This Article

Plain Text BibTeX RIS

APA Style

Redhwi, I., Fallatah, A., Alshabona, F. (2024). Hydroxyapatite: A Comprehensive Review of Its Properties, Applications, and Future Trends. International Journal of Biomedical Materials Research, 12(1), 1-6. https://doi.org/10.11648/j.ijbmr.20241201.11

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ACS Style

Redhwi, I.; Fallatah, A.; Alshabona, F. Hydroxyapatite: A Comprehensive Review of Its Properties, Applications, and Future Trends. Int. J. Biomed. Mater. Res. 2024, 12(1), 1-6. doi: 10.11648/j.ijbmr.20241201.11

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AMA Style

Redhwi I, Fallatah A, Alshabona F. Hydroxyapatite: A Comprehensive Review of Its Properties, Applications, and Future Trends. Int J Biomed Mater Res. 2024;12(1):1-6. doi: 10.11648/j.ijbmr.20241201.11

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@article{10.11648/j.ijbmr.20241201.11,
  author = {Ibraheem Redhwi and Ahmad Fallatah and Fahad Alshabona},
  title = {Hydroxyapatite: A Comprehensive Review of Its Properties, Applications, and Future Trends
},
  journal = {International Journal of Biomedical Materials Research},
  volume = {12},
  number = {1},
  pages = {1-6},
  doi = {10.11648/j.ijbmr.20241201.11},
  url = {https://doi.org/10.11648/j.ijbmr.20241201.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbmr.20241201.11},
  abstract = {Hydroxyapatite (HA) is a bioactive ceramic material which has given an important attention in the biomedical field because of its high biocompatibility and structural similarity to human’s and mammal’s bone. This study provides a comprehensive exploration of HA's properties, applications, and future trends, accentuating its potential in several domains beyond its traditional uses in bone and dental implants. HA's unique characteristics, including its osteoconductivity and ability to promote bone regeneration, make it an ideal candidate for advanced tissue engineering and drug delivery systems. The review discusses the fundamental properties of HA, such as its chemical composition, physical structure, and biological compatibility, which collectively contribute to its effectiveness in medical applications. Furthermore, ongoing research is highlighted, particularly in the development of nanostructured HA and composite materials, aimed at enhancing its mechanical properties and expanding its use in complex medical scenarios. Additionally, the implications of emerging technologies, specifically 3D printing and the potential of 4D printing, are examined. These innovations allow for the creation of personalized scaffolds tailored to individual patient needs, enhancing the prospects for regenerative medicine. The versatility of HA is further illustrated through its applications in non-medical fields, including environmental remediation and as a component in fertilizers and water purification systems. Overall, this review underscores the critical role that hydroxyapatite plays in bridging the gap between biological and synthetic materials. By synthesizing current knowledge and identifying future research directions, this work aims to pave the way for further advancements in the use of HA across various biomedical and industrial contexts, ultimately contributing to improved health outcomes and innovative material solutions.
},
 year = {2024}
}

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TY  - JOUR
T1  - Hydroxyapatite: A Comprehensive Review of Its Properties, Applications, and Future Trends

AU  - Ibraheem Redhwi
AU  - Ahmad Fallatah
AU  - Fahad Alshabona
Y1  - 2024/11/20
PY  - 2024
N1  - https://doi.org/10.11648/j.ijbmr.20241201.11
DO  - 10.11648/j.ijbmr.20241201.11
T2  - International Journal of Biomedical Materials Research
JF  - International Journal of Biomedical Materials Research
JO  - International Journal of Biomedical Materials Research
SP  - 1
EP  - 6
PB  - Science Publishing Group
SN  - 2330-7579
UR  - https://doi.org/10.11648/j.ijbmr.20241201.11
AB  - Hydroxyapatite (HA) is a bioactive ceramic material which has given an important attention in the biomedical field because of its high biocompatibility and structural similarity to human’s and mammal’s bone. This study provides a comprehensive exploration of HA's properties, applications, and future trends, accentuating its potential in several domains beyond its traditional uses in bone and dental implants. HA's unique characteristics, including its osteoconductivity and ability to promote bone regeneration, make it an ideal candidate for advanced tissue engineering and drug delivery systems. The review discusses the fundamental properties of HA, such as its chemical composition, physical structure, and biological compatibility, which collectively contribute to its effectiveness in medical applications. Furthermore, ongoing research is highlighted, particularly in the development of nanostructured HA and composite materials, aimed at enhancing its mechanical properties and expanding its use in complex medical scenarios. Additionally, the implications of emerging technologies, specifically 3D printing and the potential of 4D printing, are examined. These innovations allow for the creation of personalized scaffolds tailored to individual patient needs, enhancing the prospects for regenerative medicine. The versatility of HA is further illustrated through its applications in non-medical fields, including environmental remediation and as a component in fertilizers and water purification systems. Overall, this review underscores the critical role that hydroxyapatite plays in bridging the gap between biological and synthetic materials. By synthesizing current knowledge and identifying future research directions, this work aims to pave the way for further advancements in the use of HA across various biomedical and industrial contexts, ultimately contributing to improved health outcomes and innovative material solutions.

VL  - 12
IS  - 1
ER  -

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Author Information

Ibraheem Redhwi

Advanced Material Institution, King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia;The Center of Excellence for Advanced Materials and Manufacturing (Cambridge), King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia

Contact Email

http://orcid.org/0000-0001-9409-6346
Ahmad Fallatah

Future Mobility Institute, King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia

Contact Email

http://orcid.org/0000-0001-6483-6454
Fahad Alshabona

Advanced Material Institution, King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia;The Center of Excellence for Advanced Materials and Manufacturing (Cambridge), King Abdulaziz City for Science and Technology, Riyadh, Saudi Arabia

Contact Email

http://orcid.org/0000-0001-6966-8701

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APA Style

Redhwi, I., Fallatah, A., Alshabona, F. (2024). Hydroxyapatite: A Comprehensive Review of Its Properties, Applications, and Future Trends. International Journal of Biomedical Materials Research, 12(1), 1-6. https://doi.org/10.11648/j.ijbmr.20241201.11

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ACS Style

Redhwi, I.; Fallatah, A.; Alshabona, F. Hydroxyapatite: A Comprehensive Review of Its Properties, Applications, and Future Trends. Int. J. Biomed. Mater. Res. 2024, 12(1), 1-6. doi: 10.11648/j.ijbmr.20241201.11

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AMA Style

Redhwi I, Fallatah A, Alshabona F. Hydroxyapatite: A Comprehensive Review of Its Properties, Applications, and Future Trends. Int J Biomed Mater Res. 2024;12(1):1-6. doi: 10.11648/j.ijbmr.20241201.11

Copy | Download

@article{10.11648/j.ijbmr.20241201.11,
  author = {Ibraheem Redhwi and Ahmad Fallatah and Fahad Alshabona},
  title = {Hydroxyapatite: A Comprehensive Review of Its Properties, Applications, and Future Trends
},
  journal = {International Journal of Biomedical Materials Research},
  volume = {12},
  number = {1},
  pages = {1-6},
  doi = {10.11648/j.ijbmr.20241201.11},
  url = {https://doi.org/10.11648/j.ijbmr.20241201.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbmr.20241201.11},
  abstract = {Hydroxyapatite (HA) is a bioactive ceramic material which has given an important attention in the biomedical field because of its high biocompatibility and structural similarity to human’s and mammal’s bone. This study provides a comprehensive exploration of HA's properties, applications, and future trends, accentuating its potential in several domains beyond its traditional uses in bone and dental implants. HA's unique characteristics, including its osteoconductivity and ability to promote bone regeneration, make it an ideal candidate for advanced tissue engineering and drug delivery systems. The review discusses the fundamental properties of HA, such as its chemical composition, physical structure, and biological compatibility, which collectively contribute to its effectiveness in medical applications. Furthermore, ongoing research is highlighted, particularly in the development of nanostructured HA and composite materials, aimed at enhancing its mechanical properties and expanding its use in complex medical scenarios. Additionally, the implications of emerging technologies, specifically 3D printing and the potential of 4D printing, are examined. These innovations allow for the creation of personalized scaffolds tailored to individual patient needs, enhancing the prospects for regenerative medicine. The versatility of HA is further illustrated through its applications in non-medical fields, including environmental remediation and as a component in fertilizers and water purification systems. Overall, this review underscores the critical role that hydroxyapatite plays in bridging the gap between biological and synthetic materials. By synthesizing current knowledge and identifying future research directions, this work aims to pave the way for further advancements in the use of HA across various biomedical and industrial contexts, ultimately contributing to improved health outcomes and innovative material solutions.
},
 year = {2024}
}

Copy | Download

TY  - JOUR
T1  - Hydroxyapatite: A Comprehensive Review of Its Properties, Applications, and Future Trends

AU  - Ibraheem Redhwi
AU  - Ahmad Fallatah
AU  - Fahad Alshabona
Y1  - 2024/11/20
PY  - 2024
N1  - https://doi.org/10.11648/j.ijbmr.20241201.11
DO  - 10.11648/j.ijbmr.20241201.11
T2  - International Journal of Biomedical Materials Research
JF  - International Journal of Biomedical Materials Research
JO  - International Journal of Biomedical Materials Research
SP  - 1
EP  - 6
PB  - Science Publishing Group
SN  - 2330-7579
UR  - https://doi.org/10.11648/j.ijbmr.20241201.11
AB  - Hydroxyapatite (HA) is a bioactive ceramic material which has given an important attention in the biomedical field because of its high biocompatibility and structural similarity to human’s and mammal’s bone. This study provides a comprehensive exploration of HA's properties, applications, and future trends, accentuating its potential in several domains beyond its traditional uses in bone and dental implants. HA's unique characteristics, including its osteoconductivity and ability to promote bone regeneration, make it an ideal candidate for advanced tissue engineering and drug delivery systems. The review discusses the fundamental properties of HA, such as its chemical composition, physical structure, and biological compatibility, which collectively contribute to its effectiveness in medical applications. Furthermore, ongoing research is highlighted, particularly in the development of nanostructured HA and composite materials, aimed at enhancing its mechanical properties and expanding its use in complex medical scenarios. Additionally, the implications of emerging technologies, specifically 3D printing and the potential of 4D printing, are examined. These innovations allow for the creation of personalized scaffolds tailored to individual patient needs, enhancing the prospects for regenerative medicine. The versatility of HA is further illustrated through its applications in non-medical fields, including environmental remediation and as a component in fertilizers and water purification systems. Overall, this review underscores the critical role that hydroxyapatite plays in bridging the gap between biological and synthetic materials. By synthesizing current knowledge and identifying future research directions, this work aims to pave the way for further advancements in the use of HA across various biomedical and industrial contexts, ultimately contributing to improved health outcomes and innovative material solutions.

VL  - 12
IS  - 1
ER  -

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