The Role of Multidetector Row Computed Tomography in Biliary Tract Malignancy

Indira Narayanaswamy; Akshaya Reddy Erasu; Ram Prakash HV

doi:doi:10.11648/j.crj.20150305.13

| Peer-Reviewed

The Role of Multidetector Row Computed Tomography in Biliary Tract Malignancy

Indira Narayanaswamy, Akshaya Reddy Erasu, Ram Prakash HV

Published in Cancer Research Journal (Volume 3, Issue 5)

Received: 20 July 2015 Accepted: 7 August 2015 Published: 11 September 2015

Views: Downloads:

Download PDF

Share This Article

Twitter
Linked In
Facebook

Abstract

Early diagnosis of biliary tract tumors is important in accurate staging, to choose the best possible treatment and improve their prognosis. Multidetector row Computed Tomography is an ideal method to evaluate patients with suspected biliary tract obstruction and thereby biliary tract malignancy. Aims and Objective: To evaluate the accuracy of Multidetector row Computed Tomography (MDCT) in evaluation of level of obstruction and to study the imaging features of various causes of biliary tract malignancy. Material and Method: MDCT of 40 patients with clinically suspicion of biliary tract obstruction were prospectively reviewed and only malignant causes were included in the study. Final diagnosis was based on endoscopic retrograde cholangiopancreatography, surgical and histopathological diagnosis. The MDCT diagnosis and final diagnosis was compared for level and imaging features of malignant lesions. Results: The sensitivity, specificity, PPV, NPV and diagnostic accuracy of MDCT in determining the level of malignant obstruction is 100%, 83.33%, 97.77%, 100%, 98%, and cause of malignant obstruction is 97.73%, 83.33%, 97.72%, 83.33%, 96%. MDCT with its high sensitivity and specificity values plays an essential role in the diagnosis of malignant tumors of biliary tract and for the evaluation of therapeutic options. Conclusion: MDCT has a vital role to play in biliary tract malignancy with its high degree of accuracy in establishing the level of obstruction and in defining the imaging features of the malignant lesions.

Published in	Cancer Research Journal (Volume 3, Issue 5)
DOI	10.11648/j.crj.20150305.13
Page(s)	104-109
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2015. Published by Science Publishing Group

Keywords

Biliary Tract Obstruction, Multidetector Row Computed Tomography, Benign, Malignant

References

[1]	A. Joshi, K. Rajpal, K. Kakadiya, A. Bansal. Role of CT and MRCP in Evaluation of biliary tract obstrucyion. Curr Radiol Rep (2014) 2: 72 2.
[2]	Tasneem Lalani, Corey AC, Max PR, Mark EB, et al: ACR appropriateness criteria on jaundice. American College of Radiology 2012.
[3]	Guibaud L, Bret PM, Reinhold C, Mostafa A, Barkun ANG Diagnosis of choledocholithiasis. Value of MR cholangiography. Am J Roentgenol (1994) 163: 847–850.
[4]	David V, Reinhold C, Hochman M, Chuttani R, McKee J, Waxman I, et al. Pitfalls in the interpretation of MR cholangiopancreatography. AJR Am J Roentgenol. 1998; 170: 1055–9.
[5]	Moore KL and TVN Persaud: The Developing Human - Clinically Oriented Embryology, 7th ed. Elsevier Science (WB Saunders), Philadelphia (2003), p. 78.
[6]	Ferrari FS, Fantozzi F, Tasciotti L, Vigni F, Scotto F, Frasci P. US, MRCP, CCT and ERCP: a comparative study in 131 patients with suspected biliary obstruction. Med Sci Monit. 2005; 11:MT8–18.
[7]	Bluemke DA, Fishman EK. Spiral CT of the liver. AJR 1993; 160: 787-792.
[8]	Huang JQ, Bao XJ, Lu XH. The common causes and differential diagnosis of malignant jaundice. Zhonghua Nei Ke Za Zhi 1993; 32: 400-4.
[9]	Sharma MP, Ahuja V. Aetiological spectrum of obstructive jaundice and diagnostic ability of ultrasonography: a clinician's perspective. Trop Gastroenterol 1999; 20: 167-9.
[10]	Martin DF, Laasch HU. The biliary tract. In: Grainger RG, Allison D eds. Grainger & Allison’s Diagnostic Radiology-A textbook of medical imaging, 4th ed. Churchill Livingstone, Harcourt publishers limited, London: 2001.
[11]	Siddigue K, Ali Q, Mirza S, Jamil A, Ehsan A, Latif S, et al. Evauation of the aetiological spectrum of obstructive jaundice. J Ayub Med Coll Abbotabad 2008; 20: 62-6.
[12]	O'Connor KW. A blinded prospective study comparing four current noninvasive approaches in the differential diagnosis of medical versus surgical jaundice. Gastroenterology 1983; 84:1498-504.
[13]	Lerttumnongtum P, Muttarak M, Wasanavijit K. Clinics in Diagnostic Imaging. Singapore Medical Journal 2002; 43:592-3.
[14]	Susan HW, Elliot KF. Biliary tract obstruction the role of Spiral CT in detection and definition of disease. Clinical Imaging 1997; 21: 27-34.
[15]	Megibow AJ. Pancreatic adenocarcinoma: designing the examination to evaluate the clinical questions. Radiology 1992; 183: 297-303.
[16]	Schulte SJ, Baron RL, Teefey SA, et al. CT of the extrahepatic bile ducts: wall thickness and contrast enhancement in normal and abnormal ducts. AJR 190; 154:79-85.
[17]	Midwinter MJ, Beveridge CJ, Wilsdon JB, Bennett MK, Baudouin CJ, Charnley RM: Correlation between spiral computed tomography, endoscopic ultrasonography and findings at operation in pancreatic and ampullary tumors. Br J Surg 1999, 86: 189–193.

Cite This Article

Plain Text BibTeX RIS

APA Style

Indira Narayanaswamy, Akshaya Reddy Erasu, Ram Prakash HV. (2015). The Role of Multidetector Row Computed Tomography in Biliary Tract Malignancy. Cancer Research Journal, 3(5), 104-109. https://doi.org/10.11648/j.crj.20150305.13

Copy | Download

ACS Style

Indira Narayanaswamy; Akshaya Reddy Erasu; Ram Prakash HV. The Role of Multidetector Row Computed Tomography in Biliary Tract Malignancy. Cancer Res. J. 2015, 3(5), 104-109. doi: 10.11648/j.crj.20150305.13

Copy | Download

AMA Style

Indira Narayanaswamy, Akshaya Reddy Erasu, Ram Prakash HV. The Role of Multidetector Row Computed Tomography in Biliary Tract Malignancy. Cancer Res J. 2015;3(5):104-109. doi: 10.11648/j.crj.20150305.13

Copy | Download

@article{10.11648/j.crj.20150305.13,
  author = {Indira Narayanaswamy and Akshaya Reddy Erasu and Ram Prakash HV},
  title = {The Role of Multidetector Row Computed Tomography in Biliary Tract Malignancy},
  journal = {Cancer Research Journal},
  volume = {3},
  number = {5},
  pages = {104-109},
  doi = {10.11648/j.crj.20150305.13},
  url = {https://doi.org/10.11648/j.crj.20150305.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.crj.20150305.13},
  abstract = {Early diagnosis of biliary tract tumors is important in accurate staging, to choose the best possible treatment and improve their prognosis. Multidetector row Computed Tomography is an ideal method to evaluate patients with suspected biliary tract obstruction and thereby biliary tract malignancy. Aims and Objective: To evaluate the accuracy of Multidetector row Computed Tomography (MDCT) in evaluation of level of obstruction and to study the imaging features of various causes of biliary tract malignancy. Material and Method: MDCT of 40 patients with clinically suspicion of biliary tract obstruction were prospectively reviewed and only malignant causes were included in the study. Final diagnosis was based on endoscopic retrograde cholangiopancreatography, surgical and histopathological diagnosis. The MDCT diagnosis and final diagnosis was compared for level and imaging features of malignant lesions. Results: The sensitivity, specificity, PPV, NPV and diagnostic accuracy of MDCT in determining the level of malignant obstruction is 100%, 83.33%, 97.77%, 100%, 98%, and cause of malignant obstruction is 97.73%, 83.33%, 97.72%, 83.33%, 96%. MDCT with its high sensitivity and specificity values plays an essential role in the diagnosis of malignant tumors of biliary tract and for the evaluation of therapeutic options. Conclusion: MDCT has a vital role to play in biliary tract malignancy with its high degree of accuracy in establishing the level of obstruction and in defining the imaging features of the malignant lesions.},
 year = {2015}
}

Copy | Download

TY  - JOUR
T1  - The Role of Multidetector Row Computed Tomography in Biliary Tract Malignancy
AU  - Indira Narayanaswamy
AU  - Akshaya Reddy Erasu
AU  - Ram Prakash HV
Y1  - 2015/09/11
PY  - 2015
N1  - https://doi.org/10.11648/j.crj.20150305.13
DO  - 10.11648/j.crj.20150305.13
T2  - Cancer Research Journal
JF  - Cancer Research Journal
JO  - Cancer Research Journal
SP  - 104
EP  - 109
PB  - Science Publishing Group
SN  - 2330-8214
UR  - https://doi.org/10.11648/j.crj.20150305.13
AB  - Early diagnosis of biliary tract tumors is important in accurate staging, to choose the best possible treatment and improve their prognosis. Multidetector row Computed Tomography is an ideal method to evaluate patients with suspected biliary tract obstruction and thereby biliary tract malignancy. Aims and Objective: To evaluate the accuracy of Multidetector row Computed Tomography (MDCT) in evaluation of level of obstruction and to study the imaging features of various causes of biliary tract malignancy. Material and Method: MDCT of 40 patients with clinically suspicion of biliary tract obstruction were prospectively reviewed and only malignant causes were included in the study. Final diagnosis was based on endoscopic retrograde cholangiopancreatography, surgical and histopathological diagnosis. The MDCT diagnosis and final diagnosis was compared for level and imaging features of malignant lesions. Results: The sensitivity, specificity, PPV, NPV and diagnostic accuracy of MDCT in determining the level of malignant obstruction is 100%, 83.33%, 97.77%, 100%, 98%, and cause of malignant obstruction is 97.73%, 83.33%, 97.72%, 83.33%, 96%. MDCT with its high sensitivity and specificity values plays an essential role in the diagnosis of malignant tumors of biliary tract and for the evaluation of therapeutic options. Conclusion: MDCT has a vital role to play in biliary tract malignancy with its high degree of accuracy in establishing the level of obstruction and in defining the imaging features of the malignant lesions.
VL  - 3
IS  - 5
ER  -

Copy | Download

Author Information

Indira Narayanaswamy

Department of Radio-diagnosis, Vydehi Institiute of Medical Sciences and Research Centre, EPIP Area, Bangalore, Karnataka, India
Akshaya Reddy Erasu

Department of Radio-diagnosis, Vydehi Institiute of Medical Sciences and Research Centre, EPIP Area, Bangalore, Karnataka, India
Ram Prakash HV

Department of Radio-diagnosis, Vydehi Institiute of Medical Sciences and Research Centre, EPIP Area, Bangalore, Karnataka, India

Download PDF

Sections

Plain Text BibTeX RIS

APA Style

Indira Narayanaswamy, Akshaya Reddy Erasu, Ram Prakash HV. (2015). The Role of Multidetector Row Computed Tomography in Biliary Tract Malignancy. Cancer Research Journal, 3(5), 104-109. https://doi.org/10.11648/j.crj.20150305.13

Copy | Download

ACS Style

Indira Narayanaswamy; Akshaya Reddy Erasu; Ram Prakash HV. The Role of Multidetector Row Computed Tomography in Biliary Tract Malignancy. Cancer Res. J. 2015, 3(5), 104-109. doi: 10.11648/j.crj.20150305.13

Copy | Download

AMA Style

Indira Narayanaswamy, Akshaya Reddy Erasu, Ram Prakash HV. The Role of Multidetector Row Computed Tomography in Biliary Tract Malignancy. Cancer Res J. 2015;3(5):104-109. doi: 10.11648/j.crj.20150305.13

Copy | Download

@article{10.11648/j.crj.20150305.13,
  author = {Indira Narayanaswamy and Akshaya Reddy Erasu and Ram Prakash HV},
  title = {The Role of Multidetector Row Computed Tomography in Biliary Tract Malignancy},
  journal = {Cancer Research Journal},
  volume = {3},
  number = {5},
  pages = {104-109},
  doi = {10.11648/j.crj.20150305.13},
  url = {https://doi.org/10.11648/j.crj.20150305.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.crj.20150305.13},
  abstract = {Early diagnosis of biliary tract tumors is important in accurate staging, to choose the best possible treatment and improve their prognosis. Multidetector row Computed Tomography is an ideal method to evaluate patients with suspected biliary tract obstruction and thereby biliary tract malignancy. Aims and Objective: To evaluate the accuracy of Multidetector row Computed Tomography (MDCT) in evaluation of level of obstruction and to study the imaging features of various causes of biliary tract malignancy. Material and Method: MDCT of 40 patients with clinically suspicion of biliary tract obstruction were prospectively reviewed and only malignant causes were included in the study. Final diagnosis was based on endoscopic retrograde cholangiopancreatography, surgical and histopathological diagnosis. The MDCT diagnosis and final diagnosis was compared for level and imaging features of malignant lesions. Results: The sensitivity, specificity, PPV, NPV and diagnostic accuracy of MDCT in determining the level of malignant obstruction is 100%, 83.33%, 97.77%, 100%, 98%, and cause of malignant obstruction is 97.73%, 83.33%, 97.72%, 83.33%, 96%. MDCT with its high sensitivity and specificity values plays an essential role in the diagnosis of malignant tumors of biliary tract and for the evaluation of therapeutic options. Conclusion: MDCT has a vital role to play in biliary tract malignancy with its high degree of accuracy in establishing the level of obstruction and in defining the imaging features of the malignant lesions.},
 year = {2015}
}

Copy | Download

TY  - JOUR
T1  - The Role of Multidetector Row Computed Tomography in Biliary Tract Malignancy
AU  - Indira Narayanaswamy
AU  - Akshaya Reddy Erasu
AU  - Ram Prakash HV
Y1  - 2015/09/11
PY  - 2015
N1  - https://doi.org/10.11648/j.crj.20150305.13
DO  - 10.11648/j.crj.20150305.13
T2  - Cancer Research Journal
JF  - Cancer Research Journal
JO  - Cancer Research Journal
SP  - 104
EP  - 109
PB  - Science Publishing Group
SN  - 2330-8214
UR  - https://doi.org/10.11648/j.crj.20150305.13
AB  - Early diagnosis of biliary tract tumors is important in accurate staging, to choose the best possible treatment and improve their prognosis. Multidetector row Computed Tomography is an ideal method to evaluate patients with suspected biliary tract obstruction and thereby biliary tract malignancy. Aims and Objective: To evaluate the accuracy of Multidetector row Computed Tomography (MDCT) in evaluation of level of obstruction and to study the imaging features of various causes of biliary tract malignancy. Material and Method: MDCT of 40 patients with clinically suspicion of biliary tract obstruction were prospectively reviewed and only malignant causes were included in the study. Final diagnosis was based on endoscopic retrograde cholangiopancreatography, surgical and histopathological diagnosis. The MDCT diagnosis and final diagnosis was compared for level and imaging features of malignant lesions. Results: The sensitivity, specificity, PPV, NPV and diagnostic accuracy of MDCT in determining the level of malignant obstruction is 100%, 83.33%, 97.77%, 100%, 98%, and cause of malignant obstruction is 97.73%, 83.33%, 97.72%, 83.33%, 96%. MDCT with its high sensitivity and specificity values plays an essential role in the diagnosis of malignant tumors of biliary tract and for the evaluation of therapeutic options. Conclusion: MDCT has a vital role to play in biliary tract malignancy with its high degree of accuracy in establishing the level of obstruction and in defining the imaging features of the malignant lesions.
VL  - 3
IS  - 5
ER  -

Copy | Download