Process Study on Surface Modification of Coral Hydroxyapatite

Chang Jiahe; Su Jun; Zhang Wenyun

doi:doi:10.11648/j.ajcem.20210905.15

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Process Study on Surface Modification of Coral Hydroxyapatite

Chang Jiahe, Su Jun, Zhang Wenyun

Published in American Journal of Clinical and Experimental Medicine (Volume 9, Issue 5)

Received: 9 September 2021 Accepted: 4 October 2021 Published: 12 October 2021

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Abstract

Objective: To explore process of modifying coral hydroxyapatite by nmZnO under different conditions, the final plan is to develop a porous artificial bone composite that combines the antibacterial properties of nano zinc oxide with the porous biodegradability of coral hydroxyapatite. Methods: Coral hydroxyapatite was modified by zinc nitrate sol-gel method at 70°C in weak acid environment. White granular porous composite materials were obtained by ultrasonic, rotary stirring, drying and calcination. The composition of the composite material is analyzed using X-ray diffractomer (XRD), using scanning electron microscopy (SEM) to observe and analyze changes in the surface appearance of composite materials, using energy dispersive X-ray spectroscopy (EDX) to observe and analyze the composition of the composite surface, the results of thermogravimetric analysis were used to study the decomposition temperature and other characteristics of the composite. Results: The sol-gel method can be used for antibacterial modification on CHA surface. When the mass ratio of coral hydroxyapatite, zinc nitrate and PEG-6000 is 48:4:5, the particle size and distribution of nano-zinc oxide particles are ideal, and uniformly distributed spherical ZnO nanoparticles can be observed under scanning electron microscopy. Conclusion: Coral hydroxyapatite surface could be modified by zinc nitrate sol-gel method. The particle size of nano zinc oxide is less than 100 nanometers. The agglomeration problem of nano-particles is solved; the porous structure of CHA are not destroyed.

Published in	American Journal of Clinical and Experimental Medicine (Volume 9, Issue 5)
DOI	10.11648/j.ajcem.20210905.15
Page(s)	151-156
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Coral Hydroxyapatite, Zinc Oxide, Modification, Antibacterial Property

References

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APA Style

Chang Jiahe, Su Jun, Zhang Wenyun. (2021). Process Study on Surface Modification of Coral Hydroxyapatite. American Journal of Clinical and Experimental Medicine, 9(5), 151-156. https://doi.org/10.11648/j.ajcem.20210905.15

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ACS Style

Chang Jiahe; Su Jun; Zhang Wenyun. Process Study on Surface Modification of Coral Hydroxyapatite. Am. J. Clin. Exp. Med. 2021, 9(5), 151-156. doi: 10.11648/j.ajcem.20210905.15

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AMA Style

Chang Jiahe, Su Jun, Zhang Wenyun. Process Study on Surface Modification of Coral Hydroxyapatite. Am J Clin Exp Med. 2021;9(5):151-156. doi: 10.11648/j.ajcem.20210905.15

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@article{10.11648/j.ajcem.20210905.15,
  author = {Chang Jiahe and Su Jun and Zhang Wenyun},
  title = {Process Study on Surface Modification of Coral Hydroxyapatite},
  journal = {American Journal of Clinical and Experimental Medicine},
  volume = {9},
  number = {5},
  pages = {151-156},
  doi = {10.11648/j.ajcem.20210905.15},
  url = {https://doi.org/10.11648/j.ajcem.20210905.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajcem.20210905.15},
  abstract = {Objective: To explore process of modifying coral hydroxyapatite by nmZnO under different conditions, the final plan is to develop a porous artificial bone composite that combines the antibacterial properties of nano zinc oxide with the porous biodegradability of coral hydroxyapatite. Methods: Coral hydroxyapatite was modified by zinc nitrate sol-gel method at 70°C in weak acid environment. White granular porous composite materials were obtained by ultrasonic, rotary stirring, drying and calcination. The composition of the composite material is analyzed using X-ray diffractomer (XRD), using scanning electron microscopy (SEM) to observe and analyze changes in the surface appearance of composite materials, using energy dispersive X-ray spectroscopy (EDX) to observe and analyze the composition of the composite surface, the results of thermogravimetric analysis were used to study the decomposition temperature and other characteristics of the composite. Results: The sol-gel method can be used for antibacterial modification on CHA surface. When the mass ratio of coral hydroxyapatite, zinc nitrate and PEG-6000 is 48:4:5, the particle size and distribution of nano-zinc oxide particles are ideal, and uniformly distributed spherical ZnO nanoparticles can be observed under scanning electron microscopy. Conclusion: Coral hydroxyapatite surface could be modified by zinc nitrate sol-gel method. The particle size of nano zinc oxide is less than 100 nanometers. The agglomeration problem of nano-particles is solved; the porous structure of CHA are not destroyed.},
 year = {2021}
}

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TY  - JOUR
T1  - Process Study on Surface Modification of Coral Hydroxyapatite
AU  - Chang Jiahe
AU  - Su Jun
AU  - Zhang Wenyun
Y1  - 2021/10/12
PY  - 2021
N1  - https://doi.org/10.11648/j.ajcem.20210905.15
DO  - 10.11648/j.ajcem.20210905.15
T2  - American Journal of Clinical and Experimental Medicine
JF  - American Journal of Clinical and Experimental Medicine
JO  - American Journal of Clinical and Experimental Medicine
SP  - 151
EP  - 156
PB  - Science Publishing Group
SN  - 2330-8133
UR  - https://doi.org/10.11648/j.ajcem.20210905.15
AB  - Objective: To explore process of modifying coral hydroxyapatite by nmZnO under different conditions, the final plan is to develop a porous artificial bone composite that combines the antibacterial properties of nano zinc oxide with the porous biodegradability of coral hydroxyapatite. Methods: Coral hydroxyapatite was modified by zinc nitrate sol-gel method at 70°C in weak acid environment. White granular porous composite materials were obtained by ultrasonic, rotary stirring, drying and calcination. The composition of the composite material is analyzed using X-ray diffractomer (XRD), using scanning electron microscopy (SEM) to observe and analyze changes in the surface appearance of composite materials, using energy dispersive X-ray spectroscopy (EDX) to observe and analyze the composition of the composite surface, the results of thermogravimetric analysis were used to study the decomposition temperature and other characteristics of the composite. Results: The sol-gel method can be used for antibacterial modification on CHA surface. When the mass ratio of coral hydroxyapatite, zinc nitrate and PEG-6000 is 48:4:5, the particle size and distribution of nano-zinc oxide particles are ideal, and uniformly distributed spherical ZnO nanoparticles can be observed under scanning electron microscopy. Conclusion: Coral hydroxyapatite surface could be modified by zinc nitrate sol-gel method. The particle size of nano zinc oxide is less than 100 nanometers. The agglomeration problem of nano-particles is solved; the porous structure of CHA are not destroyed.
VL  - 9
IS  - 5
ER  -

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Author Information

Chang Jiahe

Heping Hospital Affiliated to Changzhi Medical College, Changzhi, China
Su Jun

Department of Stomatology, No. 920 Hospital of PLA, Kunming Medical University, Kunming, China
Zhang Wenyun

Department of Stomatology, No. 920 Hospital of PLA, Kunming Medical University, Kunming, China

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Plain Text BibTeX RIS

APA Style

Chang Jiahe, Su Jun, Zhang Wenyun. (2021). Process Study on Surface Modification of Coral Hydroxyapatite. American Journal of Clinical and Experimental Medicine, 9(5), 151-156. https://doi.org/10.11648/j.ajcem.20210905.15

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ACS Style

Chang Jiahe; Su Jun; Zhang Wenyun. Process Study on Surface Modification of Coral Hydroxyapatite. Am. J. Clin. Exp. Med. 2021, 9(5), 151-156. doi: 10.11648/j.ajcem.20210905.15

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AMA Style

Chang Jiahe, Su Jun, Zhang Wenyun. Process Study on Surface Modification of Coral Hydroxyapatite. Am J Clin Exp Med. 2021;9(5):151-156. doi: 10.11648/j.ajcem.20210905.15

Copy | Download

@article{10.11648/j.ajcem.20210905.15,
  author = {Chang Jiahe and Su Jun and Zhang Wenyun},
  title = {Process Study on Surface Modification of Coral Hydroxyapatite},
  journal = {American Journal of Clinical and Experimental Medicine},
  volume = {9},
  number = {5},
  pages = {151-156},
  doi = {10.11648/j.ajcem.20210905.15},
  url = {https://doi.org/10.11648/j.ajcem.20210905.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajcem.20210905.15},
  abstract = {Objective: To explore process of modifying coral hydroxyapatite by nmZnO under different conditions, the final plan is to develop a porous artificial bone composite that combines the antibacterial properties of nano zinc oxide with the porous biodegradability of coral hydroxyapatite. Methods: Coral hydroxyapatite was modified by zinc nitrate sol-gel method at 70°C in weak acid environment. White granular porous composite materials were obtained by ultrasonic, rotary stirring, drying and calcination. The composition of the composite material is analyzed using X-ray diffractomer (XRD), using scanning electron microscopy (SEM) to observe and analyze changes in the surface appearance of composite materials, using energy dispersive X-ray spectroscopy (EDX) to observe and analyze the composition of the composite surface, the results of thermogravimetric analysis were used to study the decomposition temperature and other characteristics of the composite. Results: The sol-gel method can be used for antibacterial modification on CHA surface. When the mass ratio of coral hydroxyapatite, zinc nitrate and PEG-6000 is 48:4:5, the particle size and distribution of nano-zinc oxide particles are ideal, and uniformly distributed spherical ZnO nanoparticles can be observed under scanning electron microscopy. Conclusion: Coral hydroxyapatite surface could be modified by zinc nitrate sol-gel method. The particle size of nano zinc oxide is less than 100 nanometers. The agglomeration problem of nano-particles is solved; the porous structure of CHA are not destroyed.},
 year = {2021}
}

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TY  - JOUR
T1  - Process Study on Surface Modification of Coral Hydroxyapatite
AU  - Chang Jiahe
AU  - Su Jun
AU  - Zhang Wenyun
Y1  - 2021/10/12
PY  - 2021
N1  - https://doi.org/10.11648/j.ajcem.20210905.15
DO  - 10.11648/j.ajcem.20210905.15
T2  - American Journal of Clinical and Experimental Medicine
JF  - American Journal of Clinical and Experimental Medicine
JO  - American Journal of Clinical and Experimental Medicine
SP  - 151
EP  - 156
PB  - Science Publishing Group
SN  - 2330-8133
UR  - https://doi.org/10.11648/j.ajcem.20210905.15
AB  - Objective: To explore process of modifying coral hydroxyapatite by nmZnO under different conditions, the final plan is to develop a porous artificial bone composite that combines the antibacterial properties of nano zinc oxide with the porous biodegradability of coral hydroxyapatite. Methods: Coral hydroxyapatite was modified by zinc nitrate sol-gel method at 70°C in weak acid environment. White granular porous composite materials were obtained by ultrasonic, rotary stirring, drying and calcination. The composition of the composite material is analyzed using X-ray diffractomer (XRD), using scanning electron microscopy (SEM) to observe and analyze changes in the surface appearance of composite materials, using energy dispersive X-ray spectroscopy (EDX) to observe and analyze the composition of the composite surface, the results of thermogravimetric analysis were used to study the decomposition temperature and other characteristics of the composite. Results: The sol-gel method can be used for antibacterial modification on CHA surface. When the mass ratio of coral hydroxyapatite, zinc nitrate and PEG-6000 is 48:4:5, the particle size and distribution of nano-zinc oxide particles are ideal, and uniformly distributed spherical ZnO nanoparticles can be observed under scanning electron microscopy. Conclusion: Coral hydroxyapatite surface could be modified by zinc nitrate sol-gel method. The particle size of nano zinc oxide is less than 100 nanometers. The agglomeration problem of nano-particles is solved; the porous structure of CHA are not destroyed.
VL  - 9
IS  - 5
ER  -

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