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Impact of COVID-19 on Liver Function Tests Among Sudanese Patients: A Cross-Sectional Study of Khartoum State

Introduction: Coronavirus disease 2019 (COVID-19) predominantly affects the pulmonary tract, causing mainly respiratory symptoms with some involvement of other organ systems. Liver injury has frequently been reported in COVID-19 patients. The clinical relevance of liver injury related to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection remains unclear, with a need for studies on the impact of liver function tests (LFTs) abnormalities at baseline. Methods: This cross-sectional study aimed to detect an association of LFTs with COVID-19 among Sudanese patients in Khartoum State, the Republic of Sudan's national capital city, from August to December 2021. A total of 90 patients with COVID-19 confirmed by real-time polymerase chain reaction (RT-PCR) were enrolled; their ages ranged from 20 to 80. 5 ml of venous blood samples were collected from each participant by standard venipuncture and placed into a heparin container for chemical analysis. The Mindray device was used to analyze the plasma, and the results were shown on a sizable color liquid crystal display (LCD). Results: The results showed that there was a significant difference (p. value ≤ 0.05) between levels of liver function tests according to the different categories of COVID-19 cases (mild, moderate, and severe). Also, the results indicated that there was an insignificant difference (p. value ˃ 0.05) between levels of liver function tests according to gender. Moreover, the results found that there was no correlation between liver function parameters and age. Conclusions: The present study concluded that the levels of liver function tests were affected by the severity of COVID-19 infection.

COVID-19, LFTs, Acute Respiratory Distress Syndrome

APA Style

Mogtaba Ahmed Mohammed, Alaa Abdalla Ibrahim, Ranya Adel Hamad, Jasim Mohamed Adam, Misson Shamsalfalah Ahmed, et al. (2023). Impact of COVID-19 on Liver Function Tests Among Sudanese Patients: A Cross-Sectional Study of Khartoum State. Biomedical Sciences, 9(3), 60-63. https://doi.org/10.11648/j.bs.20230903.12

ACS Style

Mogtaba Ahmed Mohammed; Alaa Abdalla Ibrahim; Ranya Adel Hamad; Jasim Mohamed Adam; Misson Shamsalfalah Ahmed, et al. Impact of COVID-19 on Liver Function Tests Among Sudanese Patients: A Cross-Sectional Study of Khartoum State. Biomed. Sci. 2023, 9(3), 60-63. doi: 10.11648/j.bs.20230903.12

AMA Style

Mogtaba Ahmed Mohammed, Alaa Abdalla Ibrahim, Ranya Adel Hamad, Jasim Mohamed Adam, Misson Shamsalfalah Ahmed, et al. Impact of COVID-19 on Liver Function Tests Among Sudanese Patients: A Cross-Sectional Study of Khartoum State. Biomed Sci. 2023;9(3):60-63. doi: 10.11648/j.bs.20230903.12

Copyright © 2023 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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